Abstract:
:Quantitative sensory testing (QST) is a widely accepted tool to investigate somatosensory changes in pain patients. Many different protocols have been developed in clinical pain research within recent years. In this review, we provide an overview of QST and tested neuroanatomical pathways, including peripheral and central structures. Based on research studies using animal and human surrogate models of neuropathic pain, possible underlying mechanisms of chronic pain are discussed. Clinically, QST may be useful for 1) the identification of subgroups of patients with different underlying pain mechanisms; 2) prediction of therapeutic outcomes; and 3) quantification of therapeutic interventions in pain therapy. Combined with sensory mapping, QST may provide useful information on the site of neural damage and on mechanisms of positive and negative somatosensory abnormalities. The use of QST in individual patients for diagnostic purposes leading to individualized therapy is an interesting concept, but needs further validation.
journal_name
Curr Pain Headache Repjournal_title
Current pain and headache reportsauthors
Pfau DB,Geber C,Birklein F,Treede RDdoi
10.1007/s11916-012-0261-3subject
Has Abstractpub_date
2012-06-01 00:00:00pages
199-206issue
3eissn
1531-3433issn
1534-3081journal_volume
16pub_type
杂志文章,评审abstract::Pain can be a significant problem for the patient with advanced cancer, particularly if bone metastases are present. Radiation therapy is efficacious and has been a mainstay in the treatment of pain from bone metastases. In the past decade, radiosurgery has developed into a successful adjunct treatment for these patie...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 历史文章,杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
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journal_title:Current pain and headache reports
pub_type: 杂志文章
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更新日期:2004-04-01 00:00:00
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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更新日期:2008-06-01 00:00:00
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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更新日期:2006-06-01 00:00:00
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-001-0036-8
更新日期:2001-06-01 00:00:00
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-014-0421-8
更新日期:2014-06-01 00:00:00
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-002-0005-x
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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更新日期:2007-12-01 00:00:00
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
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更新日期:2005-04-01 00:00:00