当前位置： SCI文献检索 > Journal of Digestive Diseases期刊下所有文献 > Relationship between pancreatic and/or extrapancreatic lesions and serum IgG and IgG4 levels in IgG4-related diseases.

Relationship between pancreatic and/or extrapancreatic lesions and serum IgG and IgG4 levels in IgG4-related diseases.

Abstract：

OBJECTIVE:We aimed to investigate the relationship between the number of involved organs or regions and serum immunoglobulin G (IgG) and immunoglobulin G4 (IgG4) levels. METHODS:The number of pancreatic and/or extrapancreatic lesions and serum IgG and IgG4 levels were examined by groups in 46 patients with IgG4-related diseases at diagnosis prior to the initiation of steroid treatment: group A (one region involved, n=7), group B (two regions involved, n=11), group C (three regions involved, n=12), group D (four regions involved, n=9) and group E (five to seven regions involved, n=7). RESULTS:Both serum IgG and IgG4 levels increased with the number of inflamed regions. Mean serum IgG levels were 15.11, 18.65, 20.92, 23.29 and 30.98 g/L while the mean IgG4 levels were 3.99, 4.70, 4.70, 9.86 and 16.49 g/L in group A, B, C, D and E, respectively. Regression analysis also suggested that IgG4 was positively correlated with the number of regions involved. Additionally, serum IgG4 was higher in patients with multiple lesions when accompanied by sclerosing sialadenitis. CONCLUSION:Patients having IgG4-related disease with high serum IgG and IgG4 levels should be systematically examined for involved lesions.

journal_name

J Dig Dis

journal_title

Journal of digestive diseases

authors

Igarashi H,Ito T,Oono T,Nakamura T,Fujimori N,Niina Y,Hijioka M,Uchida M,Lee R,Iwao R,Nakamura K,Kotoh K,Takayanagi R

doi

10.1111/j.1751-2980.2012.00583.x

subject

Has Abstract

pub_date

2012-05-01 00:00:00

pages

274-9

issue

5

eissn

1751-2972

issn

1751-2980

journal_volume

13

pub_type

杂志文章

相关文献

Journal of Digestive Diseases文献大全
  • MicroRNA profile analysis in the liver fibrotic tissues of chronic hepatitis B patients.

    abstract：OBJECTIVE:We aimed to identify the features of microRNA (miRNA) at different fibrotic stages in patients with hepatitis B virus (HBV)-related liver fibrosis. METHODS:Liver tissues were collected from 40 chronic hepatitis B (CHB) patients at fibrotic stages S0-4. Microarrays of miRNAs and genomic informatics analysis w...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12452

    authors： Chen R,Wu JC,Liu T,Qu Y,Lu LG,Xu MY

    更新日期：2017-02-01 00:00:00

  • Peritoneal mesothelioma presenting as an acute surgical abdomen due to jejunal perforation.

    abstract：BACKGROUND:Peritoneal mesothelioma is a rare disease associated with poor prognosis. Acute abdomen as the first presentation is an extremely rare occurrence. We report an exceptional case of a patient who was found to have a jejunal perforation due to infiltration of peritoneal mesothelioma. METHODS:A 62-year-old man ...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1751-2980.2007.00309.x

    authors： Salemis NS,Tsiambas E,Gourgiotis S,Mela A,Karameris A,Tsohataridis E

    更新日期：2007-11-01 00:00:00

  • Esophageal squamous cell carcinomas in a Malaysian cohort show a lack of association with human papillomavirus.

    abstract：OBJECTIVE:With an age-standardized incidence rate of 2 per 100 000, esophageal cancer is not common among Malaysians, but they are nevertheless important due to its poor prognosis. The study is to clarify whether the human papillomavirus (HPV) is associated with esophageal cancer in Malaysians as there has been no repo...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12605

    authors： Cheah PL,Koh CC,Khang TF,Goh KL,Lau PC,Chin KF,Teoh KH,Toh YF,Looi LM

    更新日期：2018-05-01 00:00:00

  • Acid inhibition effect of ilaprazole on Helicobacter pylori-negative healthy volunteers: an open randomized cross-over study.

    abstract：OBJECTIVE:The aim of this study was to evaluate the effects and safety of different doses of ilaprazole on healthy volunteers without a Helicobacter pylori infection. METHODS:A total of 12 healthy Chinese volunteers were enrolled and divided into four groups randomly, with a 5-day treatment of oral ilaprazole 5mg, 10m...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/j.1751-2980.2011.00557.x

    authors： DU YQ,Guo WY,Zou DW,Zhan XB,Li Z,Hu JH,Gong YF,He J,Lu JP,Li ZS

    更新日期：2012-02-01 00:00:00

  • Phytoceuticals: mighty but ignored weapons against Helicobacter pylori infection.

    abstract：:Helicobacter pylori (H. pylori) infection causes peptic ulcer disease, mucosa-associated lymphoid tissue (MALT) lymphomas and gastric adenocarcinomas, for which the pathogenesis of chronic gastric inflammation prevails and provides the pathogenic basis. Since the role of H. pylori infection is promoting carcinogenesis...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/j.1751-2980.2008.00334.x

    authors： Lee SY,Shin YW,Hahm KB

    更新日期：2008-08-01 00:00:00

  • Clinical features and treatment options among Chinese adults with self-reported constipation: An internet-based survey.

    abstract：OBJECTIVE:We aimed to investigate the clinical features, precipitating factors, bowel habits, bothersome symptoms and treatment strategies of individuals in China with self-reported constipation. METHODS:An internet-based survey was conducted in China. The participants had self-reported chronic constipation (≥1 sympto...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12792

    authors： Song J,Bai T,Zhang L,Hou XH

    更新日期：2019-08-01 00:00:00

  • Duodenal ulcers dominate acute upper gastrointestinal tract bleeding in childhood: a 10-year experience from Hong Kong.

    abstract：OBJECTIVE:Systematic reports on acute upper gastrointestinal bleeding in children/adolescents are scanty. The aim of this study is to analyze its presentation, pathology and outcome in Hong Kong. METHODS:A retrospective review of the hospital database for admissions up to the age of 18 years with signs of acute upper ...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1751-2980.2008.00346.x

    authors： Houben CH,Chiu PW,Lau JY,Lee KH,Ng EK,Tam YH,Yeung CK

    更新日期：2008-11-01 00:00:00

  • The gastric precancerous cascade.

    abstract：:Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first recognized histologic change is active chronic inflammation, which may persist as such: non-atrophic chronic gastritis (no gland loss), or advance to multifocal atrophic gastritis (MAG), the first real step in the precancerous casca...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1751-2980.2011.00550.x

    authors： Correa P,Piazuelo MB

    更新日期：2012-01-01 00:00:00

  • Endoscopic visualization of cancer and dysplasia in patients with ulcerative colitis following sensitization with oral 5-aminolevulinic acid.

    abstract：OBJECTIVE:Early diagnosis of colitis-associated cancer and dysplasia through surveillance endoscopy is vital for patients with ulcerative colitis (UC). This study aimed to evaluate the efficacy of autofluorescence endoscopy (AFE) using 5-aminolevulinic acid (ALA) and to investigate the fluorescence signal localization ...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12923

    authors： Kato T,Iwasaki T,Arihiro S,Saruta M

    更新日期：2020-09-01 00:00:00

  • Tuberculosis screening using IGRA and chest computed tomography in patients with inflammatory bowel disease: A retrospective study.

    abstract：OBJECTIVES:To assess the prevalence and potential risk factors of latent tuberculosis infection (LTBI) in Chinese patients with inflammatory bowel disease (IBD) and to evaluate the role of chest computed tomography (CT) in the screening of LTBI. METHODS:A single-center retrospective study was conducted and all IBD pat...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12437

    authors： Song DJ,Tong JL,Peng JC,Cai CW,Xu XT,Zhu MM,Ran ZH,Zheng Q

    更新日期：2017-01-01 00:00:00

  • Endoscopic therapy in early adenocarcinomas (Barrett's cancer) of the esophagus.

    abstract：:The incidence of early esophageal adenocarcinoma has been increasing significantly in recent decades. Prognosis depends greatly on the choice of treatment. Early cancers can be treated by endoscopic resection, whereas advanced carcinomas have to be sent for surgery. Esophageal resection is associated with high periope...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/1751-2980.12264

    authors： Knabe M,May A,Ell C

    更新日期：2015-07-01 00:00:00

  • Probiotics in the management of gastrointestinal disease: analysis of the attitudes and prescribing practices of gastroenterologists and surgeons.

    abstract：OBJECTIVE:Probiotics are increasingly advocated in the management of various gastrointestinal disorders. The aim of this study was to investigate the current attitudes and prescribing practices of surgeons and gastroenterologists for probiotics in the treatment of gastrointestinal disorders. METHODS:A questionnaire wa...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1751-2980.2011.00534.x

    authors： Cordina C,Shaikh I,Shrestha S,Camilleri-Brennan J

    更新日期：2011-12-01 00:00:00

  • The efficacy and safety of balloon dilation for unresectable malignant biliary obstruction before placement of self-expanding metal stents.

    abstract：OBJECTIVE:To evaluate whether patients with malignant biliary obstruction (MBO) benefit from balloon dilation before the placement of a self-expanding metal stent (SEMS) for palliative biliary drainage. METHODS:Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with SEMS placement for pa...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12864

    authors： Shen ZY,Wang JJ,Lu LG,Wan R,Wan XJ,Cai XB

    更新日期：2020-05-01 00:00:00

  • Inflammatory bowel disease: a survey of the epidemiology in Asia.

    abstract：:Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studies have shown an in...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/j.1751-2980.2008.00355.x

    authors： Goh K,Xiao SD

    更新日期：2009-02-01 00:00:00

  • The -A2518G polymorphism in the MCP-1 gene and inflammatory bowel disease risk: A meta-analysis.

    abstract：OBJECTIVE:The monocyte chemoattractant protein-1 (MCP-1) -A2518G gene polymorphism has been found to be involved in the susceptibility to inflammatory bowel disease (IBD); however, the results of existing studies are controversial. The aim of this meta-analysis was to assess the relationship between the MCP-1 -A2518G p...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,meta分析,评审

    doi：10.1111/1751-2980.12232

    authors： Li YW,Yang CQ,Xiao YL,Li J,Xie CX,Zhang SH,Yu Q,Wang HL,Lu WM,Chen MH

    更新日期：2015-04-01 00:00:00

  • Columnar-lined esophagus in Chinese patients with proximal gastric carcinomas.

    abstract：OBJECTIVE:To investigate the clinicopathological features of columnar-lined esophagus (CLE) in Chinese patients. METHODS:Among 182 consecutive resections of proximal gastric cancer with residual esophageal tissue, 114 were eligible for the study. The maximal lengths of CLE and superficial esophageal glands (SEG) and t...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12007

    authors： Sun Q,Huang Q,Feng AN,Fan XS,Wu HY,Mashimo H,Zhou Q,Chen J,Lauwers GY

    更新日期：2013-01-01 00:00:00

  • Effect of cytotoxic T lymphocyte-associated molecule 4 1661 gene polymorphism on its expression and transcription in ulcerative colitis.

    abstract：OBJECTIVE:Our aim was to investigate the expression of cytotoxic T lymphocyte-associated molecule 4 (CTLA-4) in ulcerative colitis (UC) and to evaluate the effect of CTLA-4 gene -1661A/G polymorphism on CTLA-4 expression and transcription. METHODS:A total of 20 UC patients and 22 healthy controls matched by age and se...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1751-2980.2010.00462.x

    authors： Jiang T,Ge LQ,Chen ZT,Li C,Zhou F,Luo Y,Xia B

    更新日期：2010-12-01 00:00:00

  • Relevant risk factors for positive lateral margin after en bloc endoscopic submucosal dissection for early gastric adenocarcinoma.

    abstract：OBJECTIVE:This study aimed to systematically assess the relevant risk factors of positive lateral margin (LM) after en bloc resection of early gastric adenocarcinoma. METHODS:A total of 242 patients who had undergone endoscopic submucosal dissection (ESD) due to early gastric lesions from January 2009 to March 2015 we...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12342

    authors： Fu QY,Cui Y,Li XB,Chen P,Chen XY

    更新日期：2016-04-01 00:00:00

  • Guidelines for the diagnosis and treatment of acute non-variceal upper gastrointestinal bleeding (2015, Nanchang, China).

    abstract：:Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is one of the most common medical emergencies in China and worldwide. In 2009, we published the "Guidelines for the diagnosis and treatment of acute non-variceal upper gastrointestinal bleeding" for the patients in China; however, during the past years numer...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,实务指引

    doi：10.1111/1751-2980.12319

    authors： Bai Y,Li ZS

    更新日期：2016-02-01 00:00:00

  • Sending family history questionnaires to patients before a colonoscopy improves genetic counseling for hereditary colorectal cancer.

    abstract：OBJECTIVES:To investigate whether sending a family history questionnaire to patients prior to undergoing colonoscopy results in an increased availability of family history and better genetic counseling. METHODS:A questionnaire was mailed to patients before they underwent outpatient colonoscopy at a university hospital...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12491

    authors： Kessels K,Eisinger JD,Letteboer TG,Offerhaus GJA,Siersema PD,Moons LMG

    更新日期：2017-06-01 00:00:00

  • Confocal laser endomicroscopy for the diagnosis of colorectal cancer in vivo.

    abstract：OBJECTIVE:To evaluate the feasibility and accuracy of confocal laser endomicroscopy (CLE) for the in vivo diagnosis of colorectal cancer (CRC) compared with conventional histology. METHODS:Consecutive patients who had undergone CLE examination for screening or surveillance colonoscopy were recruited. Suspected maligna...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12039

    authors： Liu C,Li CQ,Zuo XL,Ji R,Xie XJ,Yang YS,Li YQ

    更新日期：2013-05-01 00:00:00

  • Pathogenesis of alcoholic liver disease: interactions between parenchymal and non-parenchymal cells.

    abstract：:The development of alcoholic liver disease (ALD) is a complex process involving both the parenchymal and non-parenchymal cells in the liver. The impact of ethanol on hepatocytes can be characterized as a condition of organelle stress with multifactorial changes in hepatocellular function accumulating during ethanol ex...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/j.1751-2980.2010.00468.x

    authors： Cohen JI,Nagy LE

    更新日期：2011-02-01 00:00:00

  • Steroid treatment in patients with acute-on-chronic liver failure precipitated by hepatitis B: A 10-year cohort study in a university hospital in East China.

    abstract：OBJECTIVE:To investigate retrospectively the efficacy of steroids in patients with acute-on-chronic liver failure (ACLF) precipitated by hepatitis B. METHODS:Patients with ACLF precipitated by hepatitis B were included and categorized according to treatment modalities (steroid vs. control). Survival and clinical chara...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12691

    authors： Huang C,Yu KK,Zheng JM,Li N

    更新日期：2019-01-01 00:00:00

  • Epidemiology of inflammatory bowel diseases from west to east.

    abstract：:The incidence and prevalence of inflammatory bowel disease (IBD) show considerable variation over time and across geographical regions. The first studies on the epidemiology of IBD were mainly from traditionally high-incidence areas, such as North America, and northern and western Europe. In the last two decades, more...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/1751-2980.12449

    authors： Vegh Z,Kurti Z,Lakatos PL

    更新日期：2017-02-01 00:00:00

  • Serum biomarkers of drug-induced liver injury: Current status and future directions.

    abstract：:Drug-induced liver injury (DILI), which is caused by drugs and herbal or dietary supplements, remains a serious concern for drug developers, regulators, and clinicians; however, serum biomarkers utilized to detect and monitor DILI have not changed in decades and have limitations. Data-driven mathematical modeling that...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/1751-2980.12684

    authors： Church RJ,Watkins PB

    更新日期：2019-01-01 00:00:00

  • Surgical treatment of intestinal stricture in inflammatory bowel disease.

    abstract：:Fibroblast infiltration and collagen deposition result in structural changes in the bowel wall, and lead to strictures in intestinal inflammatory disease. While strictures can also occur in other contexts, such as malignancy, this review focuses on the surgical treatment of stricture secondary to inflammatory bowel di...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章,评审

    doi：10.1111/1751-2980.12880

    authors： Mohan HM,Coffey JC

    更新日期：2020-06-01 00:00:00

  • Follow-up study on a high risk population of gastric cancer in north China by serum pepsinogen assay.

    abstract：OBJECTIVE:To explore the features and clinical significance of serum pepsinogen (PG) assay in a follow-up study on a high-risk gastric cancer (GC) population. METHODS:A total of 444 participants from a high-risk area of GC in north China were enrolled in this follow-up study from April 1997 to December 1999. Serum PG ...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1443-9573.2007.00321.x

    authors： Sun LP,Gong YH,Wang L,Gong W,Yuan Y

    更新日期：2008-02-01 00:00:00

  • Clinical features and spiral computed tomography analysis of undifferentiated embryonic liver sarcoma in adults.

    abstract：OBJECTIVE:To summarize the clinical and spiral computed tomography (CT) features of undifferentiated embryonic liver sarcoma (UELS) in adults. METHODS:Clinical and CT findings of four adult patients with pathology-approved UELS were retrospectively analyzed with a literature review. All patients were examined using a ...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/j.1751-2980.2009.00400.x

    authors： Yang L,Chen LB,Xiao J,Han P

    更新日期：2009-11-01 00:00:00

  • Outcomes of preoperative biliary drainage from a single tertiary center: Is there still a role for plastic stents?

    abstract：OBJECTIVES:Preoperative biliary drainage (PBD) can relieve symptoms of cholestasis, but carries risk of procedural complications. Metal stents have wider lumens and longer patency, although plastic stents (PS) remain in use. We reviewed the outcomes after PBD in patients with cholestasis. METHODS:Patients with symptom...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12455

    authors： Ma MX,Chin MWS,Jennings M,Siah C,Edmunds S

    更新日期：2017-03-01 00:00:00

  • A novel approach for the detection of early gastric cancer: fluorescence spectroscopy of gastric juice.

    abstract：OBJECTIVE:This study aimed to investigate the efficacy of fluorescence spectroscopy of gastric juice for early gastric cancer (EGC) screening. METHODS:Gastric juice was collected from 101 participants who underwent endoscopy in the Outpatient Endoscopy Center of Peking University Third Hospital. The participants were ...

    journal_title：Journal of digestive diseases

    pub_type： 杂志文章

    doi：10.1111/1751-2980.12040

    authors： Deng K,Zhou LY,Lin SR,Li Y,Chen M,Geng QM,Li YW

    更新日期：2013-06-01 00:00:00