Abstract：
OBJECTIVE:A rare complication of neuroendovascular procedures is acute thromboembolism. In the setting of intraprocedural or periprocedural embolism, thrombolytics present a potentially useful therapeutic strategy. A series of patients in whom eptifibatide (a platelet glycoprotein IIb/IIIa receptor inhibitor) was used in the treatment of iatrogenic thromboembolic events occurring during elective neuroendovascular procedures is described. METHODS:Consecutive cases between May 2009 and July 2011 in which eptifibatide was administered were identified and individually reviewed for inclusion in this study (n=12). All study patients received a uniform, weight based bolus dose of 180 μg/kg of eptifibatide administered either intra-arterially through the guide catheter or intravenously. Eptifibatide infusion (2 μg/kg/min) for 24 h after bolus dose administration was continued at the discretion of the surgeon. Procedural details are described and illustrative cases presented. RESULTS:Three major categories of thromboembolic events were isolated in the course of review of study cases: acute focal neurological decline and no radiographic findings of flow limitation (eight patients), radiographic findings with or without symptoms (two patients) and persistent particulate debris during flow reversal as part of a carotid revascularization procedure (two patients). Following eptifibatide administration, no patient experienced hemorrhagic complications, and neurologic improvement to baseline level was noted in 10 of 12 patients. CONCLUSION:Eptifibatide may be an effective therapeutic strategy in the event of thromboembolism during elective neuroendovascular procedures.
journal_name
J Neurointerv Surgjournal_title
Journal of neurointerventional surgeryauthors
Dumont TM,Kan P,Snyder KV,Hopkins LN,Siddiqui AH,Levy EIdoi
10.1136/neurintsurg-2012-010271subject
Has Abstractpub_date
2013-05-01 00:00:00pages
226-30issue
3eissn
1759-8478issn
1759-8486pii
neurintsurg-2012-010271journal_volume
5pub_type
杂志文章abstract：BACKGROUND:Normative venous sinus diameters are not well established. This study seeks to compare two-dimensional digital subtraction cerebral angiographic (DSA) venous sinus calibers for patients with normal intracranial pressure (ICP) and with idiopathic intracranial hypertension (IIH). METHODS:Patients who underwen...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2020-016976
更新日期：2020-12-15 00:00:00
abstract：BACKGROUND:Debate exists as to whether patients with acute ischemic stroke who are undergoing mechanical thrombectomy should receive general anaesthesia or conscious sedation during the procedure. Using a multihospital administrative database, we compared outcomes and complications of patients receiving mechanical thro...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2014-011373
更新日期：2015-11-01 00:00:00
abstract：INTRODUCTION:The direct aspiration first pass technique (ADAPT) has been introduced as a simple and fast method for achieving good angiographic and clinical outcomes using large bore aspiration catheters for the treatment of acute ischemic stroke (AIS). We present a single center's long term experience with ADAPT. MET...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2015-012211
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Treatment of dural arteriovenous fistula involving the transverse-sigmoid region with cortical reflux is complex and treatment options may require sacrifice of the fistulous segment of the sinus. OBJECTIVE:To review our results in this subset of patients and describe current endovascular decision-making and...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2012-010497
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Volume coils were developed to improve occlusion rates of intracranial aneurysms. Previous studies have shown increased packing density and comparable occlusion rates, but subgroup analyses of aneurysm size have not been carried out. OBJECTIVE:To evaluate the safety and efficacy of the Penumbra Coil 400 (PC...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2015-012014
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:The likelihood of retreatment in patients undergoing procedures for cerebral aneurysms (CAs) has an important role in deciding the optimal treatment type. Existing determinations of retreatment rates, particularly for unruptured CAs, may not represent current clinical practice. OBJECTIVE:To use population-l...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2018-014112
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Recent reports suggest that placement of a venous sinus stent improves symptoms in selected patients with idiopathic intracranial hypertension (IIH). We report our evaluation of the long-term patency of venous stents placed for IIH. METHODS:We retrospectively reviewed our clinical database for 30 patients (...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2013-010691
更新日期：2014-04-01 00:00:00
abstract：:Rupture of a saccular intracranial artery aneurysm (IA) causes subarachnoid hemorrhage, a significant cause of stroke and death. The current treatment options, endovascular coiling and clipping, are invasive and somewhat risky. Since only some IAs rupture, those IAs at risk for rupture should be identified. However, t...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章,评审
doi：10.1136/jnis.2009.002055.rep
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:The low profile visualized intraluminal support (LVIS) device is being increasingly used for the treatment of intracranial aneurysms. Its application in the basilar artery (BA) has not yet been reported. OBJECTIVE:To evaluate the safety and early efficacy of the LVIS device for the treatment of BA aneurysms...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2018-014393
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND AND AIM:During endovascular procedures for acute ischemic stroke, catheter access to the occluded vessel may be technically difficult or impossible. The aim of this study was to access the impact of difficult catheter access to target the carotid artery on clinical outcome. METHODS:Anterior circulation stro...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2012-010438
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:The degree of stenosis of carotid arteries is recognized as an important risk factor for ischemic stroke. However, high-grade stenosis does not always cause cerebrovascular events, whereas low- to moderate-grade stenosis may often cause strokes. It has been reported that there is an association between carot...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2014-011317
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:Early intervention is desirable in patients presenting with stroke or transient ischemic attack (TIA) referable to carotid artery stenosis because of the high incidence of recurrent ischemic events within 48 h post-ictus. However, the optimal timing of performing carotid angioplasty and stenting (CAS) in thes...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2013-010744
更新日期：2014-05-01 00:00:00
abstract：:This report describes a patient who presented with subarachnoid hemorrhage and extensive right posterior inferior cerebellar artery territory infarct secondary to a dissecting aneurysm of the right intracranial vertebral artery. Urgent endovascular treatment was undertaken with plans for trapping of the diseased segme...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/jnis.2011.004952
更新日期：2012-01-01 00:00:00
abstract：:A 44-year-old man was referred to the neurointerventionalist 6 hours after sustaining a shotgun wound to the left chest, shoulder, and neck from 4 feet away. Physical examination of the chest showed a 5 cm × 5 cm gunshot entry wound on the anterior-superior aspect of the chest involving the supraclavicular and infracl...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2019-015301.rep
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The impact of the Warfarin and Aspirin for Symptomatic Intracranial Disease (WASID) data is described in combination with the commercial release of the Wingspan stenting system on the frequency of neurointervention for the treatment of symptomatic intracranial atherosclerotic disease (ICAD) in a ...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/jnis.2009.000497
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:The treatment of recurrent aneurysms after previous surgery or embolization is challenging. Little is known regarding the use of the Pipeline Embolization Device (PED) for recurrent aneurysms. OBJECTIVE:To analyze the safety and results of PED therapy for recurrent aneurysms. METHODS:Fifteen patients with ...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2012-010612
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Acute basilar artery occlusion (BAO) is a devastating disease with a high rate of mortality and morbidity, and early recanalization is crucial to achieve a good prognosis. The best treatment strategy for BAO combined with a proximal stenosis (tandem occlusion) is not yet clear. Our study aimed to...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2019-014825
更新日期：2020-01-01 00:00:00
abstract：:More than half a decade of experience and follow-up has now been accumulated with regard to flow diversion as a treatment for intracranial aneurysms; however, many uncertainties, such as the nature of aneurysmal remnants and the meaning of non-regressed, non-perfused aneurysmal masses, are still unknown. Here we discu...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2015-012093.rep
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The number of citations that an article has received can be used to evaluate its impact on the scientific community. This study aimed to identify the 100 most cited articles in the field of neurointervention and to analyze their characteristics. MATERIALS AND METHODS:We selected the 669 journals...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2016-012399
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:The DEFUSE 3 and DAWN trials have shown the benefit of thrombectomy beyond 6 hours of stroke symptom onset in carefully selected patients. OBJECTIVE:To evaluate the real-world outcomes of stent retriever thrombectomy beyond 6 hours of stroke onset using combined individual patient data from the North Americ...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2018-014272
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Adjunctive devices are commonly employed in the treatment of wide necked cerebral aneurysms. Balloon remodeling and permanent stent implantation may lead to thromboembolic complications or the need for antiplatelet use. A temporary stent that does not lead to complete flow arrest may be beneficia...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2014-011518
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:A study was undertaken to determine the typical length, diameter and taper of vessels in the anterior cerebral circulation. METHODS:The sample size was calculated at 100 patients based on similar measurements in the literature and divided into cohorts based on gender and side. These patients were consecutiv...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2012-010314
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Symptomatic intracranial atherosclerosis has been associated with a high rate of recurrent stroke. The safety of treatment of more distal atheromatous lesions with angioplasty has not been systematically reported. METHODS:We retrospectively reviewed our institutional database for all patients tr...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/jnis.2009.001818
更新日期：2010-09-01 00:00:00
abstract：:Patients with cavernous carotid fistulas (CCFs) can present with pituitary hypoperfusion and hypopituitarism; however, there are no previous reports of pituitary or hormonal abnormalities developing after CCF embolisation in an asymptomatic patient. We describe a patient with no hormonal abnormalities who developed sy...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2015-012104.rep
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:Although the anatomic course of the posterior interior cerebellar artery (PICA) is variable, it is thought to be very rare for the artery to cross midline, with an estimated incidence of 0.1%. Bihemispheric PICA crosses midline and typically serves both PICA territories. METHODS:We present 11 cases of bihemisp...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2012-010527
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Experience with the endovascular treatment of cerebral aneurysms by flow diverter devices (FDDs) is limited to four devices (Pipeline, Covidien; FRED, Microvention; Silk, Balt Extrusion; Surpass, Stryker), as reported in different studies. OBJECTIVE:To describe the initial experience and the technical innov...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2015-011743
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:The prevalence of pial arterial supply to cranial dural arteriovenous fistulas (dAVF) and its implication in the management of these fistulas is not well characterized. We performed a retrospective study to characterize pial arterial supply to dural arteriovenous fistulas and the implications for treatment. ...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2020-016374
更新日期：2020-06-29 00:00:00
abstract：BACKGROUND AND PURPOSE:There has been no prospective evaluation of vertebroplasty using a validated instrument. We describe the pain and functional status of 72 patients before and after vertebroplasty, as prospectively evaluated by the Vertebral Compression Fracture Pain and Functional Disability Questionnaire. METHO...
journal_title：Journal of neurointerventional surgery
pub_type： 临床试验,杂志文章
doi：10.1136/jnis.2009.000158
更新日期：2009-07-01 00:00:00
abstract：:The endovascular management of giant aneurysms often proves difficult with standard techniques. Obtaining distal access to allow catheter reduction is often key to approaching these aneurysms, but several anatomic challenges make this task unsafe and not feasible. Obtaining distal anchor points and performing catheter...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2014-011336.rep
更新日期：2016-07-01 00:00:00
abstract：:Intravascular foreign bodies are a known complication of medical and dental procedures. Dental anesthetic needles may be broken off and retained in the oropharynx. These needles have occasionally been reported to migrate through the oral mucosa in to deeper structures. Here we present the case of a 57-year-old man who...
journal_title：Journal of neurointerventional surgery
pub_type： 杂志文章
doi：10.1136/neurintsurg-2016-012771.rep
更新日期：2017-07-01 00:00:00
