1-Methyl-4-phenylpyridinium (MPP+) does not exhibit paraquat-like immunoreactivity.

Abstract:

:The structural analogy of paraquat with 1-methyl-4-phenylpyridinium (MPP+) has been implied in the aetiology of Parkinson's disease. The cross-reactivity of MPP+ to a specific antibody to paraquat was assessed by radioimmunoassay and was found to be very low. The results suggest that this polyclonal paraquat antibody does not mimic the MPP+ receptor.

journal_name

Toxicol Lett

journal_title

Toxicology letters

authors

Houzé P,Chappey O,Gallons H,Scherrmann JM

doi

10.1016/0378-4274(90)90238-h

subject

Has Abstract

pub_date

1990-10-01 00:00:00

pages

339-42

issue

3

eissn

0378-4274

issn

1879-3169

pii

0378-4274(90)90238-H

journal_volume

53

pub_type

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