Abstract：
OBJECTIVE:Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease, the natural course of which has not been well documented. This study aimed to perform a prospective cohort study to investigate NAFLD in a Chinese population. METHODS:Using our previous epidemiological survey, 3543 patients were followed-up for a median of 4 years (range 3.6-4.8 years). Of these patients, 624 participated in a new survey. Interviews, physical examinations, biochemical tests and abdominal ultrasonography were repeated for these patient. RESULTS:The annual incidence of NAFLD was 9.1% (male 7.3% vs female 9.7%, P=0.047). Among 117 NAFLD patients at baseline, 51 (43.6%) remained unchanged, 26 (22.2%) became worse, and 40 (34.2%) improved. Patients with simultaneous metabolic syndrome (MS) showed accelerated progression (P=0.026). For the NAFLD patients, both general annual mortality rates and cardiovascular disease deaths (both 0.54%) were significantly higher than those of patients without NAFLD (0.19% and 0.17%, P=0.005). Age and several variables related to MS were risk factors for NAFLD progression. CONCLUSIONS:The incidence of NAFLD in southern China is relatively lower in comparison with that of the developed countries. Patients with NAFLD have a benign prognosis. Variables related to MS are risk factors for NAFLD occurrence and progression.
journal_name
J Dig Disjournal_title
Journal of digestive diseasesauthors
Zhou YJ,Li YY,Nie YQ,Huang CM,Cao CYdoi
10.1111/j.1751-2980.2011.00571.xsubject
Has Abstractpub_date
2012-03-01 00:00:00pages
153-60issue
3eissn
1751-2972issn
1751-2980journal_volume
13pub_type
杂志文章abstract：:Helicobacter pylori (H. pylori) infection causes peptic ulcer disease, mucosa-associated lymphoid tissue (MALT) lymphomas and gastric adenocarcinomas, for which the pathogenesis of chronic gastric inflammation prevails and provides the pathogenic basis. Since the role of H. pylori infection is promoting carcinogenesis...
journal_title：Journal of digestive diseases
pub_type： 杂志文章,评审
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abstract：OBJECTIVE:We conducted a randomized trial aiming at improving patients' informed consent for undergoing endoscopic retrograde cholangiopancreatography (ERCP) in clinical care by comparing the efficacy of an additional educational video to written informed consent with that of written informed consent alone. METHODS:Th...
journal_title：Journal of digestive diseases
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journal_title：Journal of digestive diseases
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abstract：OBJECTIVE:With an age-standardized incidence rate of 2 per 100 000, esophageal cancer is not common among Malaysians, but they are nevertheless important due to its poor prognosis. The study is to clarify whether the human papillomavirus (HPV) is associated with esophageal cancer in Malaysians as there has been no repo...
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
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更新日期：2012-05-01 00:00:00
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pub_type： 杂志文章
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journal_title：Journal of digestive diseases
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doi：10.1111/1751-2980.12922
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
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pub_type： 杂志文章
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journal_title：Journal of digestive diseases
pub_type： 杂志文章,评审
doi：10.1111/1751-2980.12324
更新日期：2016-03-01 00:00:00
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journal_title：Journal of digestive diseases
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更新日期：2011-12-01 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2014-02-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
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更新日期：2011-08-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
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更新日期：2010-02-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章,评审
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更新日期：2014-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2016-07-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
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更新日期：2008-02-01 00:00:00
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journal_title：Journal of digestive diseases
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更新日期：2009-11-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/1751-2980.12691
更新日期：2019-01-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章,评审
doi：10.1111/1751-2980.12849
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:The efficacy of argon plasma coagulation (APC) on gastric antral vascular ectasia (GAVE) may be impaired over time and depends greatly on the application settings. Endoscopic band ligation (EBL) may be an alternative, but study on its efficacy is limited. This study aimed to evaluate and compare the clinical ...
journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12958
更新日期：2021-01-01 00:00:00
