Multifunctional CD4 T cell responses in patients with active tuberculosis.

abstract：:Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found that the proteasome...

journal_title：Scientific reports

authors： Ren H,Li F,Tian C,Nie H,Wang L,Li HH,Zheng Y

更新日期：2015-10-28 00:00:00

abstract：:In this study, we report a microfluidic device for the whole-life culture of the nematode Caenorhabditis elegans that allows the scoring of animal survival and health measures. This device referred to as the NemaLife chip features: (1) an optimized micropillar arena in which animals can crawl, (2) sieve channels that ...

journal_title：Scientific reports

authors： Rahman M,Edwards H,Birze N,Gabrilska R,Rumbaugh KP,Blawzdziewicz J,Szewczyk NJ,Driscoll M,Vanapalli SA

更新日期：2020-10-01 00:00:00

abstract：:The most consistent sex differences in cognition are found for spatial ability, in which males, on average, outperform females. Utilizing a twin design, two studies have shown that females with male co-twins perform better than females with female co-twins on a mental rotation task. According to the Twin Testosterone ...

journal_title：Scientific reports

authors： Toivainen T,Pannini G,Papageorgiou KA,Malanchini M,Rimfeld K,Shakeshaft N,Kovas Y

更新日期：2018-09-12 00:00:00

abstract：:There are approximately 1 million cryptococcal infections per year among HIV+ individuals, resulting in nearly 625,000 deaths. Cryptococcus neoformans and Cryptococcus gattii are the two most common species that cause human cryptococcosis. These two species of Cryptococcus have differences in pathogenicity, diagnosis,...

journal_title：Scientific reports

authors： Hu S,Gu F,Chen M,Wang C,Li J,Yang J,Wang G,Zhou Z,Yang Y

更新日期：2020-07-27 00:00:00

abstract：:The conformation of the German shepherd dog (GSD) varies considerably within the breed. These differences may result in large variation in the movement and limb loading and undesirable consequences to their musculoskeletal health. This study aimed to investigate the relationship between conformation and biomechanical ...

journal_title：Scientific reports

authors： Humphries A,Shaheen AF,Gómez Álvarez CB

更新日期：2020-10-15 00:00:00

abstract：:Concurrent chemoradiation therapy (CCRT) is the treatment of choice for locally advanced non-small cell lung cancer (LA-NSCLC). Several clinical trials that combine programmed cell death 1 (PD-1) axis inhibitors with radiotherapy are in development for patients with LA-NSCLC. However, the effect of CCRT on programmed ...

journal_title：Scientific reports

authors： Fujimoto D,Uehara K,Sato Y,Sakanoue I,Ito M,Teraoka S,Nagata K,Nakagawa A,Kosaka Y,Otsuka K,Imai Y,Hamakawa H,Takahashi Y,Kokubo M,Tomii K

更新日期：2017-09-12 00:00:00

abstract：:In unpredictable environments in which reliable cues for predicting environmental variation are lacking, a diversifying bet-hedging strategy for diapause exit is expected to evolve, whereby only a portion of diapausing forms will resume development at the first occurrence of suitable conditions. This study focused on ...

journal_title：Scientific reports

authors： Tarazona E,Lucas-Lledó JI,Carmona MJ,García-Roger EM

更新日期：2020-12-07 00:00:00

abstract：:Measurement-based quantum computing is one of the most promising quantum computing models. Although various universal resource states have been proposed so far, it was open whether only two Pauli bases are enough for both of universal measurement-based quantum computing and its verification. In this paper, we construc...

journal_title：Scientific reports

authors： Takeuchi Y,Morimae T,Hayashi M

更新日期：2019-09-19 00:00:00

abstract：:Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, current TNF-α blockers...

journal_title：Scientific reports

authors： Cui X,Chang L,Li Y,Lv Q,Wang F,Lin Y,Li W,Meade JD,Walden JC,Liang P

更新日期：2018-05-09 00:00:00

abstract：:Tellurite (TeO32-) is a hazardous and toxic oxyanion for living organisms. However, several microorganisms can bioconvert TeO32- into the less toxic form of elemental tellurium (Te0). Here, Rhodococcus aetherivorans BCP1 resting (non-growing) cells showed the proficiency to produce tellurium-based nanoparticles (NPs) ...

journal_title：Scientific reports

authors： Presentato A,Piacenza E,Darbandi A,Anikovskiy M,Cappelletti M,Zannoni D,Turner RJ

更新日期：2018-03-02 00:00:00

abstract：:Mast Cells (MCs) are one of the first immune cells encountered by invading pathogens. Their presence in large numbers in the superficial dermis, where Leishmania is encountered, suggests that they may play a critical role in immune responses to Leishmania. In this study the interactions of Leishmania donovani, the cau...

journal_title：Scientific reports

authors： Naqvi N,Ahuja K,Selvapandiyan A,Dey R,Nakhasi H,Puri N

更新日期：2017-10-16 00:00:00

abstract：:Ultra-high resolution optical coherence tomography (UHR-OCT) can image the corneal epithelium and Bowman's layer and measurement the thicknesses. The purpose of this study was to validate the diagnostic power of vertical thickness profiles of the corneal epithelium and Bowman's layer imaged by UHR-OCT in the diagnosis...

journal_title：Scientific reports

authors： Xu Z,Jiang J,Yang C,Huang S,Peng M,Li W,Cui L,Wang J,Lu F,Shen M

更新日期：2016-08-11 00:00:00

abstract：:Desensitisation with therapeutic plasma exchange (TPE) is essential for ABO-incompatible (ABO-I) liver transplants (LTs). However, excessive citrate load and coagulation disturbances after TPE have been poorly studied, in particular in cirrhotic patients with hypocapnic alkalosis, metabolic compensation and electrolyt...

journal_title：Scientific reports

authors： Kwon HM,Jun IG,Lee J,Moon YJ,Jung KW,Jeong HW,Park YS,Song JG,Hwang GS

更新日期：2018-04-27 00:00:00

abstract：:In this paper, we demonstrate and thoroughly analyze the activation volumetric properties of selected liquid crystals in the nematic and crystalline E phases in comparison with those reported for glass-forming liquids. In the analysis, we have employed and evaluated two entropic models (based on either total or config...

journal_title：Scientific reports

authors： Grzybowski A,Urban S,Mroz S,Paluch M

更新日期：2017-02-09 00:00:00

abstract：:This study was conducted to identify risk factors associated with AIV infections in live bird retail stalls (LBRS) in Lahore District, Pakistan. A cross-sectional survey of LBRS was conducted from December 2009-February 2010 using two-stage cluster sampling based on probability proportional to size. A total of 280 oro...

journal_title：Scientific reports

authors： Chaudhry M,Rashid HB,Angot A,Thrusfield M,Bronsvoort BMD,Capua I,Cattoli G,Welburn SC,Eisler MC

更新日期：2018-04-04 00:00:00

abstract：:To master linguistic communication, humans must acquire large vocabularies quickly and effortlessly. Efficient word learning might be facilitated by the ability to rapidly acquire novel word forms even outside the focus of attention, occurring within minutes of repetitive exposure and suggesting fast and automatic lex...

journal_title：Scientific reports

authors： Partanen EJ,Leminen A,Cook C,Shtyrov Y

更新日期：2018-10-25 00:00:00

abstract：:Solution Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy coupled with enzymatic hydrolysis (EH) with commercially available phosphatases was used to characterize phosphorus (P) compounds in extracts of the dominant aquatic macrophytes and algae in a eutrophic lake. Total extractable organic P (Po) conc...

journal_title：Scientific reports

authors： Feng W,Zhu Y,Wu F,He Z,Zhang C,Giesy JP

更新日期：2016-11-16 00:00:00

abstract：:A sensitive and specific liquid chromatographic/tandem mass spectrometric (LC-MS/MS) method was developed and validated for quantifying total and unbound docetaxel drug concentrations in plasma. Calibration curves for unbound and total docetaxel were linear over the respective ranges of 0.108~10.8 and 0.54~216 ng/mL. ...

journal_title：Scientific reports

authors： Sheu MT,Wu CY,Su CY,Ho HO

更新日期：2017-11-06 00:00:00

abstract：:We present a highly ordered surface modification layer for polymers based on ambient solution-processed triptycene (Trip) derivatives for high-mobility organic thin-film transistors (OTFTs). The nested packing of Trip molecules results in the formation of 2D hexagonal arrays, which stack one-dimensionally on the surfa...

journal_title：Scientific reports

authors： Kondo M,Kajitani T,Uemura T,Noda Y,Ishiwari F,Shoji Y,Araki T,Yoshimoto S,Fukushima T,Sekitani T

更新日期：2019-06-24 00:00:00

abstract：:Broadly neutralizing antibodies developed from the IGHV1-69 germline gene are known to bind to the stem region of hemagglutinin in diverse influenza viruses but the sequence determinants for the antigen recognition, including neutralization potency and binding affinity, are not clearly understood. Such understanding c...

journal_title：Scientific reports

authors： Tung CP,Chen IC,Yu CM,Peng HP,Jian JW,Ma SH,Lee YC,Jan JT,Yang AS

更新日期：2015-10-12 00:00:00

abstract：:Multiple factors help shape the infant intestinal microbiota early in life. Environmental conditions such as the presence of bioactive molecules from breast milk dictate gut microbial growth and survival. Infants also receive distinct, personalized, bacterial exposures leading to differential colonization. Microbial e...

journal_title：Scientific reports

authors： Lewis ZT,Sidamonidze K,Tsaturyan V,Tsereteli D,Khachidze N,Pepoyan A,Zhgenti E,Tevzadze L,Manvelyan A,Balayan M,Imnadze P,Torok T,Lemay DG,Mills DA

更新日期：2017-02-02 00:00:00

abstract：:We aimed to assess feasibility of a support vector machine (SVM) texture classifier to discriminate pathologic infiltration patterns from the normal bone marrows in MRI. This retrospective study included 467 cases, which were split into a training (n = 360) and a test set (n = 107). A sagittal T1-weighted lumbar spina...

journal_title：Scientific reports

authors： Hwang EJ,Jung JY,Lee SK,Lee SE,Jee WH

更新日期：2019-04-15 00:00:00

abstract：:In patients with type 1 diabetes mellitus (T1DM), glucose dynamics are influenced by insulin reactions, diet, lifestyle, etc., and characterized by instability and nonlinearity. With the objective of a dependable decision support system for T1DM self-management, we aim to model glucose dynamics using their nonlinear c...

journal_title：Scientific reports

authors： Frandes M,Timar B,Timar R,Lungeanu D

更新日期：2017-07-24 00:00:00

abstract：:Habitat fragmentation can reduce population viability, especially for area-sensitive species. The Minimum Area Requirements (MAR) of a population is the area required for the population's long-term persistence. In this study, the response of occupancy probability of giant pandas against habitat patch size was studied ...

journal_title：Scientific reports

authors： Qing J,Yang Z,He K,Zhang Z,Gu X,Yang X,Zhang W,Yang B,Qi D,Dai Q

更新日期：2016-12-08 00:00:00

abstract：:Bacterial communities from freshwater lakes are shaped by various factors such as nutrients, pH value, temperature, etc. Their compositions and relative abundances would undergo changes to adapt the changing environments, and in turn could affect the environments of freshwater lakes. Analyses of the freshwater lake's ...

journal_title：Scientific reports

authors： Han M,Gong Y,Zhou C,Zhang J,Wang Z,Ning K

更新日期：2016-07-27 00:00:00

abstract：:Perhaps, oxidative stress progresses pupation in some Lepidopteran insects; however, the reasons for this remain obscure. In our previous study, we clarified Bombyx mori SOD1 (BmSOD1) and B. mori SOD2 (BmSOD2) proteins respond in common to ultraviolet irradiation (UV) oxidative stress and metamorphosis. This result st...

journal_title：Scientific reports

authors： Nojima Y,Bono H,Yokoyama T,Iwabuchi K,Sato R,Arai K,Tabunoki H

更新日期：2019-10-11 00:00:00

abstract：:It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 twin cohorts in 15 countries derived from the COllaborative project of Development of Anthropometri...

journal_title：Scientific reports

authors： Jelenkovic A,Sund R,Yokoyama Y,Hur YM,Ullemar V,Almqvist C,Magnusson PK,Willemsen G,Bartels M,Beijsterveldt CEV,Bogl LH,Pietiläinen KH,Vuoksimaa E,Ji F,Ning F,Pang Z,Nelson TL,Whitfield KE,Rebato E,Llewellyn CH,Fi

更新日期：2018-04-19 00:00:00

abstract：:Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructive role in attachin...

journal_title：Scientific reports

authors： Siu GK,Zhou F,Yu MK,Zhang L,Wang T,Liang Y,Chen Y,Chan HC,Yu S

更新日期：2016-03-24 00:00:00

abstract：:Measurement of intracranial aneurysm wall motion may refine the current rupture risk estimation. A golden standard for measuring aneurysm pulsation is lacking. The aim is to evaluate magnitudes of aneurysm pulsation as published in current literature. Embase and PubMed were searched for publications containing quantit...

journal_title：Scientific reports

authors： Stam LB,Aquarius R,de Jong GA,Slump CH,Meijer FJA,Boogaarts HD

更新日期：2021-01-26 00:00:00

abstract：:Lipid droplet (LD), a multi-functional organelle, is often found to associate with other cellular membranous structures and vary in size in a given cell, which may be related to their functional diversity. Here we established a method to separate LD subpopulations from isolated CHO K2 LDs into three different size cat...

journal_title：Scientific reports

authors： Zhang S,Wang Y,Cui L,Deng Y,Xu S,Yu J,Cichello S,Serrero G,Ying Y,Liu P

更新日期：2016-07-08 00:00:00