Study of two G-protein coupled receptor variants of human trace amine-associated receptor 5.

abstract：:The incisive evaluation of psychological stress may be required to determine the exercise performance of stressed hosts. We investigated objective markers of psychological stress that reflect exercise performance, focusing on the neutrophil function. We used murine water-immersion restraint (WIR) stress for our assess...

journal_title：Scientific reports

authors： Kinoshita M,Nakashima H,Nakashima M,Koga M,Toda H,Koiwai K,Morimoto Y,Miyazaki H,Saitoh D,Suzuki H,Seki S

更新日期：2019-03-14 00:00:00

abstract：:State of charge (SOC) is a crucial index used in the assessment of electric vehicle (EV) battery storage systems. Thus, SOC estimation of lithium-ion batteries has been widely investigated because of their fast charging, long-life cycle, and high energy density characteristics. However, precise SOC assessment of lithi...

journal_title：Scientific reports

authors： Hannan MA,Lipu MSH,Hussain A,Ker PJ,Mahlia TMI,Mansor M,Ayob A,Saad MH,Dong ZY

更新日期：2020-03-13 00:00:00

abstract：:Oral microbiome dysbiosis has been associated with various local and systemic human diseases such as dental caries, periodontal disease, obesity, and cardiovascular disease. Bacterial composition may be affected by age, oral health, diet, and geography, although information about the natural variation found in the gen...

journal_title：Scientific reports

authors： Burcham ZM,Garneau NL,Comstock SS,Tucker RM,Knight R,Metcalf JL,Genetics of Taste Lab Citizen Scientists.

更新日期：2020-02-07 00:00:00

abstract：:Whether age has any impact on the risk of lymph node (LN) metastasis in patients with early-stage non-small cell lung cancer (NSCLC) remains controversial. Therefore, we aimed to objectively compare the risk of LN metastasis between elderly and young patients so as to justify for age-different extent of surgical resec...

journal_title：Scientific reports

authors： Deng HY,Zhou J,Wang RL,Jiang R,Qiu XM,Zhu DX,Tang XJ,Zhou Q

更新日期：2020-06-12 00:00:00

abstract：:Protein colocalisation is often studied using pixel intensity-based coefficients such as Pearson, Manders, Li or Costes. However, these methods cannot be used to study object-based colocalisations in biological systems. Therefore, a novel method is required to automatically identify regions of fluorescent signal in tw...

journal_title：Scientific reports

authors： Khushi M,Napier CE,Smyth CM,Reddel RR,Arthur JW

更新日期：2017-08-21 00:00:00

abstract：:Using classical molecular dynamics with a more reliable reactive LCBOPII potential, we have performed a detailed study on the direct graphite-to-diamond phase transition. Our results reveal a new so-called "wave-like buckling and slipping" mechanism, which controls the transformation from hexagonal graphite to cubic d...

journal_title：Scientific reports

authors： Xie H,Yin F,Yu T,Wang JT,Liang C

更新日期：2014-08-04 00:00:00

abstract：:K-Ras is the most frequently mutated oncoprotein in human cancers, and G12D is its most prevalent mutation. To understand how G12D mutation impacts K-Ras function, we need to understand how it alters the regulation of its dynamics. Here, we present local changes in K-Ras structure, conformation and dynamics upon G12D ...

journal_title：Scientific reports

authors： Vatansever S,Erman B,Gümüş ZH

更新日期：2019-08-13 00:00:00

abstract：:Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders. Using mice with transgenic PTN overexpression in the brain (Ptn-Tg), we have found a positive correlation between iNos and Tnfα mRNA and Ptn mRNA levels in the prefrontal cortex (PFC) of LPS-treated mice. PTN is an inhibitor...

journal_title：Scientific reports

authors： Fernández-Calle R,Galán-Llario M,Gramage E,Zapatería B,Vicente-Rodríguez M,Zapico JM,de Pascual-Teresa B,Ramos A,Ramos-Álvarez MP,Uribarri M,Ferrer-Alcón M,Herradón G

更新日期：2020-11-20 00:00:00

abstract：:Immune parameters show characteristic normal baseline levels and variance in the population. We characterised the degree of inter-individual and within-individual variation over one-year time period in 33 immune cell subsets by flow cytometry in peripheral blood mononuclear cells from 43 healthy young adult volunteers...

journal_title：Scientific reports

authors： Kanodia P,Kaur G,Coshic P,Chatterjee K,Neeman T,George A,Rath S,Bal V,Prabhu SB

更新日期：2019-10-14 00:00:00

abstract：:The balance between ovarian folliculogenesis and follicular atresia is critical for female fertility and is strictly regulated by a complex network of neuroendocrine and intra-ovarian signals. Despite the numerous functions executed by granulosa cells (GCs) in ovarian physiology, the role of multifunctional proteins a...

journal_title：Scientific reports

authors： Arcos A,de Paola M,Gianetti D,Acuña D,Velásquez ZD,Miró MP,Toro G,Hinrichsen B,Muñoz RI,Lin Y,Mardones GA,Ehrenfeld P,Rivera FJ,Michaut MA,Batiz LF

更新日期：2017-09-18 00:00:00

abstract：:Over the last decades, great strides were made in the development of novel implants for the treatment of bone defects. The increasing versatility and complexity of these implant designs request for concurrent advances in means to assess in vivo the course of induced bone formation in preclinical models. Since its disc...

journal_title：Scientific reports

authors： Lienemann PS,Metzger S,Kiveliö AS,Blanc A,Papageorgiou P,Astolfo A,Pinzer BR,Cinelli P,Weber FE,Schibli R,Béhé M,Ehrbar M

更新日期：2015-05-19 00:00:00

abstract：:During interpersonal interactions, people perform actions with different forms of vitality, communicating their positive or negative attitude toward others. For example, a handshake can be "soft" or "vigorous", a caress can be 'kind' or 'rushed'. While previous studies have shown that the dorso-central insula is a key...

journal_title：Scientific reports

authors： Di Cesare G,Vannucci F,Rea F,Sciutti A,Sandini G

更新日期：2020-10-09 00:00:00

abstract：:The Sinorhizobium meliloti (S. meliloti) strain CCNWSX0020 displayed tolerance to high levels exposures of multiple metals and growth promotion of legume plants grown in metal-contaminated soil. However, the mechanism of metal-resistant strain remains unknown. We used five P1B-ATPases deletions by designating as ∆copA...

journal_title：Scientific reports

authors： Lu M,Li Z,Liang J,Wei Y,Rensing C,Wei G

更新日期：2016-07-05 00:00:00

abstract：:The F1F0-ATP synthase, an enzyme complex, is mainly located on the mitochondrial inner membrane or sometimes cytomembrane to generate or hydrolyze ATP, play a role in cell proliferation. This study focused on the role of F1F0-ATP synthase in keratinocyte differentiation, and its relationship with intracellular and ext...

journal_title：Scientific reports

authors： Xiaoyun X,Chaofei H,Weiqi Z,Chen C,Lixia L,Queping L,Cong P,Shuang Z,Juan S,Xiang C

更新日期：2017-02-17 00:00:00

abstract：:Marine pollution is a significant issue in recent decades, with the increase in industries and their waste harming the environment and ecosystems. Notably, the rise in shellfish industries contributes to tons of shellfish waste composed of up to 58% chitin. Chitin, the second most ample polymer next to cellulose, is i...

journal_title：Scientific reports

authors： Subramanian K,Sadaiappan B,Aruni W,Kumarappan A,Thirunavukarasu R,Srinivasan GP,Bharathi S,Nainangu P,Renuga PS,Elamaran A,Balaraman D,Subramanian M

更新日期：2020-07-17 00:00:00

abstract：:Soybean seeds are an important source of vegetable oil and biomaterials. The content of individual triacylglycerol species (TAG) in soybean seeds is difficult to quantify in an accurate and rapid way. The present study establishes an approach to quantify TAG species in soybean seeds utilizing an electrospray ionizatio...

journal_title：Scientific reports

authors： Li M,Butka E,Wang X

更新日期：2014-10-10 00:00:00

abstract：:Using analytical expressions for the magnetization textures of thin submicron-sized magnetic cylinders in vortex state, we derive closed-form algebraic expressions for the ensuing small-angle neutron scattering (SANS) cross sections. Specifically, for the perpendicular and parallel scattering geometries, we have compu...

journal_title：Scientific reports

authors： Metlov KL,Michels A

更新日期：2016-04-26 00:00:00

abstract：:Determining the shape of plant cellulose microfibrils is critical for understanding plant cell wall molecular architecture and conversion of cellulose into biofuels. Only recently has it been determined that these cellulose microfibrils are composed of 18 cellulose chains rather than 36 polymers arranged in a diamond-...

journal_title：Scientific reports

authors： Kubicki JD,Yang H,Sawada D,O'Neill H,Oehme D,Cosgrove D

更新日期：2018-09-18 00:00:00

abstract：:Frequencies of CpG and UpA dinucleotides in most plant RNA virus genomes show degrees of suppression comparable to those of vertebrate RNA viruses. While pathways that target CpG and UpAs in HIV-1 and echovirus 7 genomes and restrict their replication have been partly characterised, whether an analogous process drives...

journal_title：Scientific reports

authors： Ibrahim A,Fros J,Bertran A,Sechan F,Odon V,Torrance L,Kormelink R,Simmonds P

更新日期：2019-12-04 00:00:00

abstract：:The increasing availability of electronic health care records has provided remarkable progress in the field of population health. In particular the identification of disease risk factors has flourished under the surge of available data. Researchers can now access patient data across a broad range of demographics and g...

journal_title：Scientific reports

authors： Feldman K,Stiglic G,Dasgupta D,Kricheff M,Obradovic Z,Chawla NV

更新日期：2016-07-27 00:00:00

abstract：:Tumor oxygenation has been correlated with treatment outcome for radiotherapy. In this work, the dependence of tumor oxygenation on tumor vascularity and blood oxygenation was determined quantitatively in a 4D stochastic computational model of head and neck squamous cell carcinoma (HNSCC) tumor growth and angiogenesis...

journal_title：Scientific reports

authors： Forster JC,Douglass MJJ,Harriss-Phillips WM,Bezak E

更新日期：2017-09-08 00:00:00

abstract：:In this work, we demonstrate an innovative approach, combing a novel active screen plasma (ASP) technique with green chemical synthesis, for a direct fabrication of uniform Pt nanowire arrays on large-area supports. The ASP treatment enables in-situ N-doping and surface modification to the support surface, significant...

journal_title：Scientific reports

authors： Du S,Lin K,Malladi SK,Lu Y,Sun S,Xu Q,Steinberger-Wilckens R,Dong H

更新日期：2014-09-22 00:00:00

abstract：:Our understanding of innate immune responses in human rectal mucosal tissues (RM) and their contributions to promoting or restricting HIV transmission is limited. We defined the RM composition of innate and innate-like cell subsets, including plasmacytoid dendritic cells; CD1c + myeloid DCs; neutrophils; macrophages; ...

journal_title：Scientific reports

authors： Smith SA,Murray PM,Amancha PK,Ackerley CG,Hu YJ,Amara RR,Kelley CF

更新日期：2020-11-19 00:00:00

abstract：:Choosing an option increases a person's preference for that option. This phenomenon, called choice-based learning (CBL), has been investigated separately in the contexts of internally guided decision-making (IDM, e.g., preference judgment), for which no objectively correct answer exists, and externally guided decision...

journal_title：Scientific reports

authors： Nakao T,Kanayama N,Katahira K,Odani M,Ito Y,Hirata Y,Nasuno R,Ozaki H,Hiramoto R,Miyatani M,Northoff G

更新日期：2016-08-31 00:00:00

abstract：:Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 ad...

journal_title：Scientific reports

authors： Butkevich E,Härtig W,Nikolov M,Erck C,Grosche J,Urlaub H,Schmidt CF,Klopfenstein DR,Chua JJ

更新日期：2016-06-01 00:00:00

abstract：:BMPs are multifunctional growth factors implicated in regulating the ovarian function as key intra-ovarian factors. Biological effects of BMPs are mediated through binding with membrane bound receptors like BMPR-IB and initiating downstream Smad signaling pathway. FecB mutation, regarded as a loss of function mutation...

journal_title：Scientific reports

authors： Kumar S,Punetha M,Jose B,Bharati J,Khanna S,Sonwane A,Green JA,Whitworth K,Sarkar M

更新日期：2020-11-24 00:00:00

abstract：:Although the rapid urease test (RUT) is a simple method for detecting Helicobacter pylori (H. pylori) infection, it requires sufficient biopsy samples and its sensitivity varies depending on the site and condition of H. pylori infection. We compared the diagnostic performance of a "sweeping method" for H. pylori detec...

journal_title：Scientific reports

authors： Noh CK,Lee GH,Park JW,Roh J,Han JH,Lee E,Park B,Lim SG,Shin SJ,Cheong JY,Kim JH,Lee KM

更新日期：2020-10-28 00:00:00

abstract：:Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KRAS mutations in a l...

journal_title：Scientific reports

authors： Leal LF,de Paula FE,De Marchi P,de Souza Viana L,Pinto GDJ,Carlos CD,Berardinelli GN,Miziara JE,da Silva CM,Silva ECA,Pereira R,de Oliveira MA,Scapulatempo-Neto C,Reis RM

更新日期：2019-03-01 00:00:00

abstract：:Deoxynivalenol (DON) is one of the most abundant mycotoxins and exerts many adverse effects on humans and animals. To date, the transporting mechanism of DON in mammalian cells remains unclear. In this study, the parallel artificial membrane permeability assay (PAMPA), Transwell models and metabolic inhibitors were us...

journal_title：Scientific reports

authors： Li X,Mu P,Wen J,Deng Y

更新日期：2017-07-19 00:00:00

abstract：:The use of impedance-based label free cell analysis is increasingly popular and has many different applications. Here, we report that a real-time cell analyzer (RTCA) can be used to study the stimulation of Natural Killer (NK) cells. Engagement of NK cells via plate-bound antibodies directed against different activati...

journal_title：Scientific reports

authors： Fasbender F,Watzl C

更新日期：2018-03-21 00:00:00