Locations of marine animals revealed by carbon isotopes.

abstract：:Systems with a discrete rotational symmetry [Formula: see text] where [Formula: see text] that also have electromagnetic duality symmetry exhibit zero backscattering. The impact of breaking one of the two symmetries on the emerging backscattering has not yet been systematically studied. Here, we investigate the effect...

journal_title：Scientific reports

authors： Abdelrahman MI,Slivina E,Rockstuhl C,Fernandez-Corbaton I

更新日期：2021-01-18 00:00:00

abstract：:Human papillomaviruses enter host cells via a clathrin-independent endocytic pathway involving tetraspanin proteins. However, post-endocytic trafficking required for virus capsid disassembly remains unclear. Here we demonstrate that the early trafficking pathway of internalised HPV particles involves tetraspanin CD63,...

journal_title：Scientific reports

authors： Gräßel L,Fast LA,Scheffer KD,Boukhallouk F,Spoden GA,Tenzer S,Boller K,Bago R,Rajesh S,Overduin M,Berditchevski F,Florin L

更新日期：2016-08-31 00:00:00

abstract：:Anti-cytokine therapeutic antibodies have been demonstrated to be effective in the treatment of several auto-immune disorders. However, The problems in antibody manufacture and the immunogenicity caused by multiple doses of antibodies inspire people to use auto-cytokine as immunogen to induce anti-cytokine antibodies....

journal_title：Scientific reports

authors： Liu C,Zhao Y,He W,Wang W,Chen Y,Zhang S,Ma Y,Gohda J,Ishida T,Walter TS,Owens RJ,Stuart DI,Ren J,Gao B

更新日期：2015-09-28 00:00:00

abstract：:Ataxia-telangiectasia (AT) and related disorders feature cancer predisposition, neurodegeneration, and immunodeficiency resulting from failure to respond to DNA damage. Hypomorphic mutations in MRE11 cause an AT-like disorder (ATLD) with variable clinical presentation. We have sought to understand how diverse MRE11 mu...

journal_title：Scientific reports

authors： Hartlerode AJ,Regal JA,Ferguson DO

更新日期：2018-07-04 00:00:00

abstract：:Two embedded sulfur atoms in a novel [2 + 2] Schiff-base macrocyclic dinuclear Zn(II) complex were found to be easily autoxidized to the sulfone units on air exposure, and the resultant sulfone-functionalized macrocyclic complex was obtained by the post-modification strategy exhibiting enhanced antimicrobial activitie...

journal_title：Scientific reports

authors： Feng G,Shi Y,Zhang L,Shi R,Huang W,Wang R

更新日期：2017-11-21 00:00:00

abstract：:Thymol, as a dietary monoterpene, is a phenol derivative of cymene, which is the major component of the essential oil of Trachyspermum ammi (L.). It shows multiple biological activities: antifungal, antibacterial, antivirus and anti-inflammatory. T. ammi, commonly known as ajowan, belongs to Apiaceae and is an importa...

journal_title：Scientific reports

authors： Soltani Howyzeh M,Sadat Noori SA,Shariati J V,Amiripour M

更新日期：2018-09-07 00:00:00

abstract：:Despite the quintessential role that music plays in human societies by enabling us to release and share emotions with others, traces of its evolutionary origins in other species remain scarce. Drumming like humans whilst producing music is practically unheard of in our most closely related species, the great apes. Alt...

journal_title：Scientific reports

authors： Dufour V,Poulin N,Charlotte Curé,Sterck EH

更新日期：2015-06-17 00:00:00

abstract：:Recent reports have shown that very high dose rate radiation (35-100 Gy/second) referred to as FLASH tends to spare the normal tissues while retaining the therapeutic effect on tumor. We undertook a series of experiments to assess if ultra-high dose rate of 35 Gy/second can spare the immune system in models of radiati...

journal_title：Scientific reports

authors： Venkatesulu BP,Sharma A,Pollard-Larkin JM,Sadagopan R,Symons J,Neri S,Singh PK,Tailor R,Lin SH,Krishnan S

更新日期：2019-11-20 00:00:00

abstract：:Fatigue is a very common non-motor symptom in Parkinson disease (PD) patients. It included physical fatigue and mental fatigue. The potential mechanisms of mental fatigue involving serotonergic dysfunction and abnormal iron metabolism are still unknown. Therefore, we evaluated the fatigue symptoms, classified PD patie...

journal_title：Scientific reports

authors： Zuo LJ,Yu SY,Hu Y,Wang F,Piao YS,Lian TH,Yu QJ,Wang RD,Li LX,Guo P,Du Y,Zhu RY,Jin Z,Wang YJ,Wang XM,Chan P,Chen SD,Wang YJ,Zhang W

更新日期：2016-12-21 00:00:00

abstract：:Although the glucose lowering effect of dipeptidyl peptidase-4 (DPP4) inhibitors is well established, several potential serious acute safety concerns have been raised including acute kidney injury, respiratory tract infections, and acute pancreatitis. Using the UK-based Clinical Practice Research Datalink (CPRD), we i...

journal_title：Scientific reports

authors： Gamble JM,Donnan JR,Chibrikov E,Twells LK,Midodzi WK,Majumdar SR

更新日期：2018-10-11 00:00:00

abstract：:Little information is available regarding the adverse effects of pesticides on natural honey bee populations. This study highlights the detrimental effects of pesticides on honey bee olfaction through behavioural studies, scanning electron microscopic imaging of antennal sensillae and confocal microscopic studies of h...

journal_title：Scientific reports

authors： Chakrabarti P,Rana S,Bandopadhyay S,Naik DG,Sarkar S,Basu P

更新日期：2015-07-27 00:00:00

abstract：:We show a coding method of suspension array based on the laser induced breakdown spectroscopy (LIBS), which promotes the barcodes from analog to digital. As the foundation of digital optical barcodes, nanocrystals encoded microspheres are prepared with self-assembly encapsulation method. We confirm that digital multip...

journal_title：Scientific reports

authors： He Q,Liu Y,He Y,Zhu L,Zhang Y,Shen Z

更新日期：2016-11-03 00:00:00

abstract：:Identifying vital nodes in complex networks is a critical problem in the field of network theory. To this end, the Collective. Influence (CI) algorithm has been introduced and shows high efficiency and scalability in searching for the influential nodes in. the optimal percolation model. However, the crucial part of th...

journal_title：Scientific reports

authors： Zhu F

更新日期：2018-09-28 00:00:00

abstract：:Metabolic images from Positron Emission Tomography (PET) are used routinely for diagnosis, follow-up or treatment planning purposes of cancer patients. In this study we aimed at determining if radiomic features extracted from 18F-Fluoro Deoxy Glucose (FDG) PET images could mirror tumor transcriptomics. In this study w...

journal_title：Scientific reports

authors： Tixier F,Cheze-le-Rest C,Schick U,Simon B,Dufour X,Key S,Pradier O,Aubry M,Hatt M,Corcos L,Visvikis D

更新日期：2020-03-27 00:00:00

abstract：:The development of bulk, three-dimensional (3D), macroporous polymers with high permeability, large surface area and large volume is highly desirable for a range of applications in the biomedical, biotechnological and environmental areas. The experimental techniques currently used are limited to the production of smal...

journal_title：Scientific reports

authors： Savina IN,Ingavle GC,Cundy AB,Mikhalovsky SV

更新日期：2016-02-17 00:00:00

abstract：:Vitiligo is characterized by death or functional defects of epidermal melanocytes through still controversial pathogenic process. Previously, we showed that mitochondria-driven pre-senescent phenotype diminishes the capability of vitiligo melanocytes to cope with stressful stimuli. In the current study, we investigate...

journal_title：Scientific reports

authors： Dell'Anna ML,Ottaviani M,Kovacs D,Mirabilii S,Brown DA,Cota C,Migliano E,Bastonini E,Bellei B,Cardinali G,Ricciardi MR,Tafuri A,Picardo M

更新日期：2017-10-20 00:00:00

abstract：:This work presents a new method for assisting in the identification process of missing persons in several contexts, such as enforced disappearances. We apply a Bayesian technique to incorporate non-genetic variables in the construction of prior information. In that way, we can learn from the already-solved cases of a ...

journal_title：Scientific reports

authors： Caridi I,Alvarez EE,Somigliana C,Puerto MS

更新日期：2020-03-19 00:00:00

abstract：:Apolipoprotein E4 (E4) and type 2 diabetes are major risk factors for cognitive decline and late onset Alzheimer's disease (AD). E4-associated phenotypes and insulin resistance (IR) share several features and appear to interact in driving cognitive dysfunction. However, shared mechanisms that could explain their overl...

journal_title：Scientific reports

authors： Johnson LA,Torres ER,Impey S,Stevens JF,Raber J

更新日期：2017-03-08 00:00:00

abstract：:Insulin signaling governs many processes including glucose homeostasis and metabolism, and is therapeutically used to treat hyperglycemia in diabetes. We demonstrated that insulin-induced Akt activation enhances the sensitivity to TGF-β by directing an increase in cell surface TGF-β receptors from a pool of intracellu...

journal_title：Scientific reports

authors： Budi EH,Hoffman S,Gao S,Zhang YE,Derynck R

更新日期：2019-11-18 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BM-MSCs) are used in tissue engineering because of their migration characters. However, BM-MSCs have limitations in terms of reaching injuries and self-renewal. Therefore, enhancement of BM-MSC migration is important for therapeutic applications. Here, we assessed whether galectin-3...

journal_title：Scientific reports

authors： Gao Q,Xia Y,Liu L,Huang L,Liu Y,Zhang X,Xu K,Wei J,Hu Y,Mu Y,Li K

更新日期：2016-05-24 00:00:00

abstract：:Fossils of the sponge Angulosuspongia sinensis from calcareous mudstones of the middle and upper part of the Kaili Formation (Cambrian Stage 5) in the Jianhe area of Guizhou province, South China, exhibit an apparently reticulate pattern, characteristic of the Vauxiidae. Energy Dispersive X-Ray Spectrometry (EDS) and ...

journal_title：Scientific reports

authors： Yang XL,Zhao YL,Babcock LE,Peng J

更新日期：2017-02-21 00:00:00

abstract：:The dorsal striatum is a brain region involved in action control, with dorsomedial striatum (DMS) mediating goal-directed actions and dorsolateral striatum (DLS) mediating habitual actions. Presynaptic long-term synaptic depression (LTD) plasticity at glutamatergic inputs to dorsal striatum mediates many dorsal striat...

journal_title：Scientific reports

authors： Muñoz B,Haggerty DL,Atwood BK

更新日期：2020-04-29 00:00:00

abstract：:On the basis of diet induced obesity and KO mice models, nitric oxide is implied to play an important role in the initiation of dyslipidemia induced insulin resistance. However, outcomes using iNOS KO mice have so far remained inconclusive. The present study aimed to assess IR in iNOS KO mice after 5 weeks of LFD feed...

journal_title：Scientific reports

authors： Kanuri BN,Kanshana JS,Rebello SC,Pathak P,Gupta AP,Gayen JR,Jagavelu K,Dikshit M

更新日期：2017-01-20 00:00:00

abstract：:Recent advances in the field of Tissue Engineering allowed to control the three-dimensional organization of engineered constructs. Cell pattern imaging and in vivo follow-up remain a major hurdle in in situ bioprinting onto deep tissues. Magnetic Resonance Imaging (MRI) associated with Micron-sized superParamagnetic I...

journal_title：Scientific reports

authors： Kérourédan O,Ribot EJ,Fricain JC,Devillard R,Miraux S

更新日期：2018-10-25 00:00:00

abstract：:Urate transporter 1 (URAT1/SLC22A12), a urate transporter gene, is a causative gene for renal hypouricemia type 1. Among several reported nonsynonymous URAT1 variants, R90H (rs121907896) and W258X (rs121907892) are frequent causative mutations for renal hypouricemia. However, no case-control study has evaluated the re...

journal_title：Scientific reports

authors： Sakiyama M,Matsuo H,Shimizu S,Nakashima H,Nakamura T,Nakayama A,Higashino T,Naito M,Suma S,Hishida A,Satoh T,Sakurai Y,Takada T,Ichida K,Ooyama H,Shimizu T,Shinomiya N

更新日期：2016-01-29 00:00:00

abstract：:Spores of pathogenic fungi are virtually ubiquitous and cause human disease and severe losses in crops. The endophytic fungi Alternaria species produce host-selective phytotoxins. Alt a 1 is a strongly allergenic protein found in A. alternata that causes severe asthma. Despite the well-established pathogenicity of Alt...

journal_title：Scientific reports

authors： Garrido-Arandia M,Silva-Navas J,Ramírez-Castillejo C,Cubells-Baeza N,Gómez-Casado C,Barber D,Pozo JC,Melendi PG,Pacios LF,Díaz-Perales A

更新日期：2016-09-16 00:00:00

abstract：:Leptin has a central role in the maintenance of energy homeostasis, and its sensitivity is influenced by both the photoperiod and dietary polyphenols. The aim of this study was to investigate the effect of seasonal consumption of polyphenol-rich fruits on the hypothalamic leptin signaling system in non-obese and obese...

journal_title：Scientific reports

authors： Ibars M,Aragonès G,Ardid-Ruiz A,Gibert-Ramos A,Arola-Arnal A,Suárez M,Bladé C

更新日期：2018-09-11 00:00:00

abstract：:A new bicentennial series of the Australian monsoon strength based on historical wind observations has allowed for the assessment of the variability of this system since the early 19th century. Our series covers a period in which the scarcity of meteorological observations in the area had precluded the evaluation of l...

journal_title：Scientific reports

authors： Gallego D,García-Herrera R,Peña-Ortiz C,Ribera P

更新日期：2017-11-23 00:00:00

abstract：:The endo-levanase BT1760 of a human gut commensal Bacteroides thetaiotaomicron randomly cuts a β-2,6-linked fructan, levan, into fructo-oligosaccharides providing a prebiotic substrate for gut microbiota. Here we introduce the crystal structure of BT1760 at resolution of 1.65 Å. The fold of the enzyme is typical for G...

journal_title：Scientific reports

authors： Ernits K,Eek P,Lukk T,Visnapuu T,Alamäe T

更新日期：2019-06-11 00:00:00

abstract：:A sensitive and specific liquid chromatographic/tandem mass spectrometric (LC-MS/MS) method was developed and validated for quantifying total and unbound docetaxel drug concentrations in plasma. Calibration curves for unbound and total docetaxel were linear over the respective ranges of 0.108~10.8 and 0.54~216 ng/mL. ...

journal_title：Scientific reports

authors： Sheu MT,Wu CY,Su CY,Ho HO

更新日期：2017-11-06 00:00:00