Abstract:
STUDY OBJECTIVE:To estimate the concentration of natural killer (NK) cells in the peripheral blood in patients with and without endometriosis. DESIGN:Case-control study (Canadian Task Force classification II-2). SETTING:Tertiary referral hospital. PATIENTS:One hundred fifty-five patients who had undergone videolaparoscopy were divided into 2 groups: those with endometriosis (n = 100) and those without endometriosis (n = 55). INTERVENTIONS:The percentage of NK cells relative to peripheral lymphocytes was quantified at flow cytometry in 155 patients who had undergone laparoscopy. In addition to verifying the presence of endometriosis, stage of disease and the sites affected were also evaluated. MEASUREMENTS AND MAIN RESULTS:The mean (SD) percentage of NK cells was higher (15.3% [9.8%]) in patients with endometriosis than in the group without the disease (10.6% [5.8%]) (p < .001). The percentage of NK cells was highest (19.8 [10.3%]) in patients with advanced stages of endometriosis and in those in whom the rectosigmoid colon was affected. In a statistical model of probability, the association of this marker (NK cells ≥11%) with the presence of symptoms such as pain and intestinal bleeding during menstruation and the absence of previous pregnancy yielded a 78% likelihood of the rectosigmoid colon being affected. CONCLUSION:Compared with patients without endometriosis, those with endometriosis demonstrate a higher concentration of peripheral NK cells. The percentage of NK cells is greater, primarily in patients with advanced stages of endometriosis involving the rectosigmoid colon. Therefore, it may serve as a diagnostic marker for this type of severe endometriosis, in particular if considered in conjunction with the symptoms.
journal_name
J Minim Invasive Gynecoljournal_title
Journal of minimally invasive gynecologyauthors
Dias JA Jr,Podgaec S,de Oliveira RM,Carnevale Marin ML,Baracat EC,Abrão MSdoi
10.1016/j.jmig.2011.12.021subject
Has Abstractpub_date
2012-05-01 00:00:00pages
317-24issue
3eissn
1553-4650issn
1553-4669pii
S1553-4650(11)01432-4journal_volume
19pub_type
杂志文章abstract:STUDY OBJECTIVE:Because of the rapid growth of minimally invasive surgical procedures, we developed an ultrathin fiberscopic imaging system for laser surgery that could be an important instrument for clinical use in an office setting. METHODS AND MAIN RESULTS:A new device, consisting of a custom 1.1-mm diameter flexib...
journal_title:Journal of minimally invasive gynecology
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更新日期:2015-09-01 00:00:00
abstract:STUDY OBJECTIVE:Although all ectopic pregnancies are associated with risk of hemorrhage, cornual pregnancies are feared for catastrophic hemorrhage and uncontrollable bleeding. The maternal mortality rate can be as high as 2.5%, which is 7 times higher than the mortality rate for ectopic pregnancies in general. Differe...
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journal_title:Journal of minimally invasive gynecology
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doi:10.1016/j.jmig.2011.08.725
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abstract::Laparoendoscopic single-site surgery (LESS) and natural orifice translumenal endoscopic surgery are now being used in gynecologic oncologic procedures. We used our expertise with LESS to perform nerve-sparing laparoscopic radical hysterectomy. A 45-year-old woman with stage IA2 cervical cancer was referred to us. The ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2013.04.019
更新日期:2013-11-01 00:00:00
abstract::We present the case of a 17-year-old nulliparous woman with a history of obesity (body mass index 36.2 kg/m(2)), type 2 diabetes, and polycystic ovary syndrome, who was diagnosed with grade 1 endometrioid adenocarcinoma without radiological evidence of myometrial invasion or metastatic disease. After failure of a fert...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2015.03.017
更新日期:2015-07-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
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journal_title:Journal of minimally invasive gynecology
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doi:10.1016/j.jmig.2009.06.012
更新日期:2009-09-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
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更新日期:2013-11-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
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doi:10.1016/j.jmig.2011.09.006
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journal_title:Journal of minimally invasive gynecology
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abstract:STUDY OBJECTIVE:To describe the feasibility of performing Essure hysteroscopic sterilization immediately after NovaSure global endometrial ablation (GEA). DESIGN:Descriptive feasibility study (Canadian Task Force classification III). SETTING:Midwestern United States academic medical center. PATIENTS:Twenty-five wome...
journal_title:Journal of minimally invasive gynecology
pub_type: 临床试验,杂志文章
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更新日期:2007-07-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
abstract::Endometriosis is a common condition that affects as many as 10% to 20% of women of reproductive age. Because of the subtle clinical signs and symptoms and limitations of imaging methods, the diagnosis is frequently delayed or missed, with serious consequences including hypertension, hydronephrosis, and loss of kidney ...
journal_title:Journal of minimally invasive gynecology
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更新日期:2010-01-01 00:00:00
abstract:STUDY OBJECTIVE:To determine patient and hospital characteristics that were associated with undergoing laparoscopic hysterectomy compared with abdominal hysterectomy. DESIGN:Canadian Task Force Classification II-3. METHODS:In this retrospective cohort study, we analyzed the 2010 Healthcare Cost and Utilization Projec...
journal_title:Journal of minimally invasive gynecology
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doi:10.1016/j.jmig.2013.08.709
更新日期:2014-03-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
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doi:10.1016/j.jmig.2012.02.006
更新日期:2012-07-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2016.02.011
更新日期:2016-07-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2004.12.026
更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
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doi:10.1016/j.jmig.2007.04.002
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journal_title:Journal of minimally invasive gynecology
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更新日期:2019-01-01 00:00:00
abstract:STUDY OBJECTIVE:To provide surgeons with techniques for preemptive analgesia during minimally invasive gynecologic surgery. Postoperative pain management is an important component of patient care after gynecologic surgery. There have been numerous advances in pain management, including studies that show that preoperati...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.09.768
更新日期:2019-02-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2019.06.010
更新日期:2020-01-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
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更新日期:2015-05-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
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更新日期:2006-03-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2016.01.028
更新日期:2016-07-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2010.02.005
更新日期:2010-05-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.12.003
更新日期:2019-01-01 00:00:00
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journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.01.028
更新日期:2018-01-01 00:00:00