Abstract：
OBJECTIVE:To compare lung function in wheezy infants, with risk factors of asthma and with some immunological parameters which may be useful as predictors of subsequent asthma. METHODS:The data of 241 infants aged 5–36 mo, with recurrent wheeze (≥3 episodes of physician confirmed wheeze) prior to receiving inhaled corticosteroids or anti-leukotrine agents was retrospectively analyzed. They were subdivided into 2 subgroups; those with asthma risk factors (132 patients) and those without (109 patients) Also, 67 healthy, age and sex matched children without recurrent wheezes were taken as control group. Total serum IgE, eosinophilic percentage, tPTEF/tE (time to peak expiratory flow to total expiratory time), total respiratory system compliance (Crs) and resistance of the respiratory system (Rrs) was done for patients and control groups. RESULTS:Wheezy infants had a significantly higher eosinophilic percentage and total serum IgE as well as a significantly lower pulmonary function parameters when compared to healthy controls. Wheezy infants with positive family history of asthma and those who had not been breast fed showed significant reduction in the mean values of tPTEF/tE and increased both eosinophilic percentage and total serum IgE. Crs was significantly decreased in wheezy infants with positive seasonal variations and those who had increased both eosinophilic percentage and total serum IgE. Rrs showed significant increase in wheezy infants with positive family history of atopy and those who had increased eosinophilic percentage and increased total serum IgE. CONCLUSIONS:Lung function, eosinophilic percentage, total serum IgE and asthma risk factors could be used as predictors for ongoing wheeze in this subset of children.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Zedan M,Nasef N,El-Bayoumy M,El-Assmy M,Attia G,Zedan M,AlWakeel A,Kandil S,Laimon W,Fouda Adoi
10.1007/s12098-012-0694-zsubject
Has Abstractpub_date
2012-09-01 00:00:00pages
1176-80issue
9eissn
0019-5456issn
0973-7693journal_volume
79pub_type
杂志文章abstract：:Neonates are among those patients generating the highest hospital costs in recent years. There are no published data on the costs of neonatal intensive care in our country. The aim of our study was to analyse the cost of neonatal intensive care in a tertiary care unit. The average hospital charges per day were higher ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02752301
更新日期：1998-03-01 00:00:00
abstract：OBJECTIVES:To screen for variants in the MC4R and LEP genes in 46 patients with clinical suspicion of non-syndromic early onset severe obesity (NEOSO). METHODS:Children with early onset obesity satisfying WHO criteria of obesity were studied. The MC4R and LEP genes were sequenced using a PCR amplicon based NGS on Illu...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-019-03129-6
更新日期：2020-02-01 00:00:00
abstract：:This study reports the clinical picture and measles virus antibody titres in 32 patients with cases of suspected subacute sclerosing panencephalitis (SSPE). The history of myoclonic jerks, mental regression, inability to walk and slurred speech, were noted in these cases. The EEG showed generalised periodic complexes ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02825445
更新日期：1991-11-01 00:00:00
abstract：:Primary vesicoureteric reflux (VUR) is the most common inherited structural urinary tract disorder, conforming closely to autosomal dominant transmission. A pair of monozygotic siblings is described exhibiting a remarkably parallel clinical course. VUR grade II was diagnosed in girl A during urinary tract infection at...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-008-0061-2
更新日期：2008-03-01 00:00:00
abstract：:Pulmonary arterial hypertension in children can occur secondary to shunt lesion like ventricular septal defect, patent ductus arteriosus or it may be idiopathic, the so called primary pulmonary hypertension (PPH). The progression of PPH is usually rapid in children as compared to adults and the mean survival is 2-3 ye...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2000-03-01 00:00:00
abstract：OBJECTIVE:To find out the incidence and natural history of IgMN in India. METHODS:Renal biopsies of children ≤12 y age of last 6 y were retrospectively evaluated. Their clinical and biochemical presentation were correlated. Patients with systemic diseases/disorders were excluded from the study. RESULTS:Immunoglobulin...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-012-0693-0
更新日期：2012-08-01 00:00:00
abstract：:The authors present a case of a preterm newborn with congenital infection of herpes simplex virus type 2. The patient was treated with newly recommended high intravenous doses of acyclovir. It can be supposed that it reduces mortality, but the high morbidity continues to be a problem. ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVES:To identify biomarkers for neuronal injury and outcome in perinatal asphyxia. METHODS:This prospective cohort study was done in authors' level III NICU involving 80 neonates - 40 babies with perinatal asphyxia and 40 weight and gender matched normal neonates. Levels of cytokines IL-6, IL -1β, IL-2 and TNF -...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-014-1575-4
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the implications of a newly defined severity scoring of empyema in children for the prediction of surgical management and to compare the length of hospitalization as an outcome measure of patients treated using medical therapy, salvage video-assisted thoracoscopic surgery (VATS) vs early elective ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02724404
更新日期：2005-12-01 00:00:00
abstract：:The authors report a case of Kawasaki disease that manifested in a newborn and presented at the age of 6 weeks of age with coronary artery aneurysms. ...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02724106
更新日期：2004-04-01 00:00:00
abstract：:Low hemoglobin and low MCHC levels were indicative of high incidence of iron deficiency in preschool children. The extent of iron deficiency as assessed by serum ferritin and free erythrocyte protoporphyrin showed a different trend. While FEP levels were highly suggestive of extensive iron deficiency (in 40-45% of chi...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02759985
更新日期：1992-03-01 00:00:00
abstract：:Genetic counseling is a process of communicating medical aspects about a genetic disorder, especially the information regarding risk of occurrence as recurrence of the disease in the family and preventive options. Accurate diagnosis of the affected member is of paramount importance for genetic counseling. Special gene...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02723098
更新日期：2004-02-01 00:00:00
abstract：:Death is a natural process, but the definition of death varies depending on the cultural and religious background, all over the world. The historical development of the concept and the current criteria in the determination of brain death must be well understood. Termination of life support measures in a brain dead chi...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02730887
更新日期：1998-07-01 00:00:00
abstract：:The study was conducted to assess copper and zinc levels in neonate's serum, mother's serum, neonate's hair and urine and to ascertain association between them. It is of concern whether zinc and copper deficiency is present at birth and maternal blood and breast milk zinc and copper levels have any effect on this. The...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02726255
更新日期：1999-09-01 00:00:00
abstract：:Incidence of allergic disorders in children has increased significantly over time due to environmental and life-style changes. These include allergic rhinitis, atopic dermatitis, allergic conjunctivitis, food allergies, bronchial asthma, drug allergies, insect bites and anaphylaxis; most being IgE-mediated type 1 hype...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-017-2436-8
更新日期：2018-01-01 00:00:00
abstract：:Oral lesions of tuberculosis though uncommon, are seen both in the primary as well as the secondary stages of the disease. In secondary tuberculosis, the oral manifestations are accompanied by lesions in the lung, lymph nodes, or any other organ system of the body. This can be detected by the usual clinical history an...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-010-0266-z
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To identify the causes and contributing factors of persistent pneumonia in children. METHODS:41 cases with persistent pneumonia were investigated (biochemical, microbiological, histopathological, immunological and radiological tests) to find out the underlying cause. RESULTS:Out of 41 cases, 8 had pulmonary...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-009-0272-1
更新日期：2009-12-01 00:00:00
abstract：:Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are disorders of pulmonary inflammation characterized by hypoxemia and respiratory failure. Children have varying incidence of ALI/ARDS from 2.2 to 16 per 100,000 pediatric population associated with high morbidity, mortality, and financial burden....
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-010-0169-z
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU). METHODS:A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at l...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-014-1415-6
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To determine the safety and efficacy of off label usage of Recombinant activated factor VII (rFVIIa) in children with severe bleeding in non-hemophiliac children with diverse etiologies like leukemia, post hematopoietic stem cell transplantation, dengue shock syndrome and Glanzmann thrombasthenia. METHOD:Med...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-011-0364-6
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:To find the prevalence of associated anomalies in children with anorectal malformation (ARM). METHODS:One hundred and forty patients (80 males and 60 females) with expand were studied to detect associated anomalies and to find their prevalence. High and low type of ARM was seen in 52.14% and 47.86% of patien...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02724292
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the social consequences of dialysis on children and their parents. METHODS:From January through June 2012 short structured interviews with parents or caregivers of children on peritoneal dialysis (PD) or hemodialysis (HD) who were followed up at King Abdulaziz University Hospital, King Faisal Sp...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-013-1236-z
更新日期：2014-10-01 00:00:00
abstract：:The aim of the study was to assess the functional aspects and the staffing at Pulse Polio immunisations posts. Interns and medical students conducted the survey in eighty seven pulse polio immunisation posts scattered all over National Capital Territory of Delhi on 18th January 1997. A pre-tested structured format con...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02730902
更新日期：1998-07-01 00:00:00
abstract：:Children with upper airway obstruction are both unique and variable in their presentation and management, often posing a challenge to the pediatrician. Several anatomical and physiologic peculiarities make a child vulnerable to develop an obstruction of upper airways. The characteristic finding in upper airway obstruc...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-015-1811-6
更新日期：2015-08-01 00:00:00
abstract：:Superior mediastinal syndrome (SMS) is an uncommon manifestation of malignant neoplastic disease in children. The commonest neoplastic cause of SMS is Non Hodgkin lymphoma. Acute myeloid leukemia (AML) as a cause of SMS is extremely uncommon in childhood. The authors hereby report a case of a child with AML who presen...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-012-0799-4
更新日期：2013-02-01 00:00:00
abstract：:Asthma is fairly common in pediatric age group and the suffering due to asthma continues to increase despite excellent treatments available. One of the four major components of asthma management is patient education and is critical to the success of asthma management. Reasons for continued suffering include that our m...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,病人教育讲义,评审
doi：
更新日期：2001-09-01 00:00:00
abstract：:We studied the auditory brainstem responses of 50 high risk neonates from NICU and compared with those of 25 normal neonates in order to determine the percentage of significant auditory impairment in NICU and correlated it to various risk factors. Infants with the risk factors of low birth weight, hyperbilirubinemia, ...
journal_title：Indian journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/BF02725499
更新日期：1997-11-01 00:00:00
abstract：:Hypothyroidism and type 1 diabetes mellitus (T1DM) constitute two common endocrine disorders of children. Both these are chronic conditions which require long term follow-up for optimum control, can be missed on initial presentation unless a high index of suspicion is maintained and may be associated with adverse outc...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-013-1101-0
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVES:The authors measured and recorded the physical (outdoor playing) and mental (home study) activity behavior and blood pressure amongst school going children and observed their association with the blood pressure levels. METHOD:It was a cross sectional school-based study from 12 primary schools; selected by s...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/BF02724095
更新日期：2004-04-01 00:00:00
abstract：:Type 1 diabetes mellitus is considered a common form of diabetes mellitus in young people. Type 1 diabetes in infants is rare. However, the condition is rare in infants. Type 1 diabetes has not been reported in the literature in 45 days old child of an Indian population. Type 1 diabetes typically begins between the ag...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s12098-009-0009-1
更新日期：2009-04-01 00:00:00
