Sauropod dinosaur osteoderms from the Late Cretaceous of Madagascar.

Abstract:

:Osteoderms are bones embedded within the dermis, and are common to select members of most major tetrapod lineages. The largest known animals that bear osteoderms are members of Titanosauria, a diverse clade of sauropod dinosaurs. Here we report on two titanosaur osteoderms recovered from the Upper Cretaceous Maevarano Formation of Madagascar. Each osteoderm was discovered in association with a partial skeleton representing a distinct ontogenetic stage of the titanosaur Rapetosaurus krausei. Combined, these specimens provide novel insights into the arrangement and function of titanosaur osteoderms. Taphonomic data confirm that Rapetosaurus developed only limited numbers of osteoderms in its integument. The adult-sized osteoderm is the most massive integumentary skeletal element yet discovered, with an estimated volume of 9.63 litres. Uniquely, this specimen possesses an internal cavity equivalent to more than half its total volume. Large, hollow osteoderms may have functioned as mineral stores in fecund, rapidly growing titanosaurs inhabiting stressed environments.

journal_name

Nat Commun

journal_title

Nature communications

authors

Curry Rogers K,D'Emic M,Rogers R,Vickaryous M,Cagan A

doi

10.1038/ncomms1578

subject

Has Abstract

pub_date

2011-11-29 00:00:00

pages

564

issn

2041-1723

pii

ncomms1578

journal_volume

2

pub_type

杂志文章
  • Synergistic effect of quinary molten salts and ruthenium catalyst for high-power-density lithium-carbon dioxide cell.

    abstract::With a recent increase in interest in metal-gas batteries, the lithium-carbon dioxide cell has attracted considerable attention because of its extraordinary carbon dioxide-capture ability during the discharge process and its potential application as a power source for Mars exploration. However, owing to the stable lit...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-14121-1

    authors: Baek K,Jeon WC,Woo S,Kim JC,Lee JG,An K,Kwak SK,Kang SJ

    更新日期:2020-01-23 00:00:00

  • The role of mechanics in biological and bio-inspired systems.

    abstract::Natural systems frequently exploit intricate multiscale and multiphasic structures to achieve functionalities beyond those of man-made systems. Although understanding the chemical make-up of these systems is essential, the passive and active mechanics within biological systems are crucial when considering the many nat...

    journal_title:Nature communications

    pub_type: 杂志文章,评审

    doi:10.1038/ncomms8418

    authors: Egan P,Sinko R,LeDuc PR,Keten S

    更新日期:2015-07-06 00:00:00

  • Asymmetric assembly of high-value α-functionalized organic acids using a biocatalytic chiral-group-resetting process.

    abstract::The preparation of α-functionalized organic acids can be greatly simplified by adopting a protocol involving the catalytic assembly of achiral building blocks. However, the enzymatic assembly of small amino acids and aldehydes to form numerous α-functionalized organic acids is highly desired and remains a significant ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-06241-x

    authors: Song W,Wang JH,Wu J,Liu J,Chen XL,Liu LM

    更新日期:2018-09-19 00:00:00

  • Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex.

    abstract::Maintenance of working memory is thought to involve the activity of prefrontal neuronal populations with strong recurrent connections. However, it was recently shown that distractors evoke a morphing of the prefrontal population code, even when memories are maintained throughout the delay. How can a morphing code main...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-12841-y

    authors: Parthasarathy A,Tang C,Herikstad R,Cheong LF,Yen SC,Libedinsky C

    更新日期:2019-11-01 00:00:00

  • Broadband on-chip single-photon spectrometer.

    abstract::Single-photon counters are single-pixel binary devices that click upon the absorption of a photon but obscure its spectral information, whereas resolving the color of detected photons has been in critical demand for frontier astronomical observation, spectroscopic imaging and wavelength division multiplexed quantum co...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-12149-x

    authors: Cheng R,Zou CL,Guo X,Wang S,Han X,Tang HX

    更新日期:2019-09-10 00:00:00

  • Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.

    abstract::Emerging data suggest that locoregional cancer therapeutic approaches with oncolytic viruses can lead to systemic anti-tumour immunity, although the appropriate targets for intratumoral immunomodulation using this strategy are not known. Here we find that intratumoral therapy with Newcastle disease virus (NDV), in add...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms14340

    authors: Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP

    更新日期:2017-02-13 00:00:00

  • Coordination mode engineering in stacked-nanosheet metal-organic frameworks to enhance catalytic reactivity and structural robustness.

    abstract::Optimising the supported modes of atom or ion dispersal onto substrates, to synchronously integrate high reactivity and robust stability in catalytic conversion, is an important yet challenging area of research. Here, theoretical calculations first show that three-coordinated copper (Cu) sites have higher activity tha...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-10547-9

    authors: Huang C,Dong J,Sun W,Xue Z,Ma J,Zheng L,Liu C,Li X,Zhou K,Qiao X,Song Q,Ma W,Zhang L,Lin Z,Wang T

    更新日期:2019-06-25 00:00:00

  • Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis.

    abstract::The plasma membrane is uniquely enriched in phosphatidylserine (PtdSer). This anionic phospholipid is restricted almost exclusively to the inner leaflet of the plasmalemma. Because of their high density, the headgroups of anionic lipids experience electrostatic repulsion that, being exerted asymmetrically, is predicte...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-017-01554-9

    authors: Hirama T,Lu SM,Kay JG,Maekawa M,Kozlov MM,Grinstein S,Fairn GD

    更新日期:2017-11-09 00:00:00

  • Photobactericidal activity activated by thiolated gold nanoclusters at low flux levels of white light.

    abstract::The emergence of antibiotic resistant bacteria is a major threat to the practice of modern medicine. Photobactericidal agents have obtained significant attention as promising candidates to kill bacteria, and they have been extensively studied. However, to obtain photobactericidal activity, an intense white light sourc...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-15004-6

    authors: Hwang GB,Huang H,Wu G,Shin J,Kafizas A,Karu K,Toit HD,Alotaibi AM,Mohammad-Hadi L,Allan E,MacRobert AJ,Gavriilidis A,Parkin IP

    更新日期:2020-03-05 00:00:00

  • Enolate chemistry with anion-π interactions.

    abstract::Anion-π interactions occur on the surface of π-acidic aromatic planes with positive quadrupole moments. Their ability to contribute to the binding and transport of anions has been demonstrated recently. However, their ability to stabilize anionic reactive intermediates and transition states remains essentially unexplo...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4911

    authors: Zhao Y,Sakai N,Matile S

    更新日期:2014-05-21 00:00:00

  • Protein-targeted corona phase molecular recognition.

    abstract::Corona phase molecular recognition (CoPhMoRe) uses a heteropolymer adsorbed onto and templated by a nanoparticle surface to recognize a specific target analyte. This method has not yet been extended to macromolecular analytes, including proteins. Herein we develop a variant of a CoPhMoRe screening procedure of single-...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms10241

    authors: Bisker G,Dong J,Park HD,Iverson NM,Ahn J,Nelson JT,Landry MP,Kruss S,Strano MS

    更新日期:2016-01-08 00:00:00

  • Machine learning-based prediction of acute coronary syndrome using only the pre-hospital 12-lead electrocardiogram.

    abstract::Prompt identification of acute coronary syndrome is a challenge in clinical practice. The 12-lead electrocardiogram (ECG) is readily available during initial patient evaluation, but current rule-based interpretation approaches lack sufficient accuracy. Here we report machine learning-based methods for the prediction o...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-17804-2

    authors: Al-Zaiti S,Besomi L,Bouzid Z,Faramand Z,Frisch S,Martin-Gill C,Gregg R,Saba S,Callaway C,Sejdić E

    更新日期:2020-08-07 00:00:00

  • An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment.

    abstract::How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. The intermediate immune infiltration cluster (Cluster B) is associated ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-13329-5

    authors: Tekpli X,Lien T,Røssevold AH,Nebdal D,Borgen E,Ohnstad HO,Kyte JA,Vallon-Christersson J,Fongaard M,Due EU,Svartdal LG,Sveli MAT,Garred Ø,OSBREAC.,Frigessi A,Sahlberg KK,Sørlie T,Russnes HG,Naume B,Kristensen VN

    更新日期:2019-12-03 00:00:00

  • Quantitative fermentation of unpretreated transgenic poplar by Caldicellulosiruptor bescii.

    abstract::Microbial fermentation of lignocellulosic biomass to produce industrial chemicals is exacerbated by the recalcitrant network of lignin, cellulose and hemicelluloses comprising the plant secondary cell wall. In this study, we show that transgenic poplar (Populus trichocarpa) lines can be solubilized without any pretrea...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-11376-6

    authors: Straub CT,Khatibi PA,Wang JP,Conway JM,Williams-Rhaesa AM,Peszlen IM,Chiang VL,Adams MWW,Kelly RM

    更新日期:2019-08-07 00:00:00

  • Structural basis of IL-23 antagonism by an Alphabody protein scaffold.

    abstract::Protein scaffolds can provide a promising alternative to antibodies for various biomedical and biotechnological applications, including therapeutics. Here we describe the design and development of the Alphabody, a protein scaffold featuring a single-chain antiparallel triple-helix coiled-coil fold. We report affinity-...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms6237

    authors: Desmet J,Verstraete K,Bloch Y,Lorent E,Wen Y,Devreese B,Vandenbroucke K,Loverix S,Hettmann T,Deroo S,Somers K,Henderikx P,Lasters I,Savvides SN

    更新日期:2014-10-30 00:00:00

  • The child brain computes and utilizes internalized maternal choices.

    abstract::As children grow, they gradually learn how to make decisions independently. However, decisions like choosing healthy but less-tasty foods can be challenging for children whose self-regulation and executive cognitive functions are still maturing. We propose a computational decision-making process in which children esti...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms11700

    authors: Lim SL,Cherry JB,Davis AM,Balakrishnan SN,Ha OR,Bruce JM,Bruce AS

    更新日期:2016-05-24 00:00:00

  • Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets.

    abstract::Knowledge of key drivers and therapeutic targets in mucosal melanoma is limited due to the paucity of comprehensive mutation data on this rare tumor type. To better understand the genomic landscape of mucosal melanoma, here we describe whole genome sequencing analysis of 67 tumors and validation of driver gene mutatio...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-11107-x

    authors: Newell F,Kong Y,Wilmott JS,Johansson PA,Ferguson PM,Cui C,Li Z,Kazakoff SH,Burke H,Dodds TJ,Patch AM,Nones K,Tembe V,Shang P,van der Weyden L,Wong K,Holmes O,Lo S,Leonard C,Wood S,Xu Q,Rawson RV,Mukhopadhyay P

    更新日期:2019-07-18 00:00:00

  • ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation.

    abstract::A human cell contains hundreds to thousands of mitochondrial DNA (mtDNA) packaged into nucleoids. Currently, the segregation and allocation of nucleoids are thought to be passively determined by mitochondrial fusion and division. Here we provide evidence, using live-cell super-resolution imaging, that nucleoids can be...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18202-4

    authors: Qin J,Guo Y,Xue B,Shi P,Chen Y,Su QP,Hao H,Zhao S,Wu C,Yu L,Li D,Sun Y

    更新日期:2020-09-08 00:00:00

  • Licensing MLH1 sites for crossover during meiosis.

    abstract::During meiosis, homologous chromosomes synapse and recombine at sites marked by the binding of the mismatch repair protein MLH1. In hexaploid wheat, the Ph1 locus has a major effect on whether crossover occurs between homologues or between related homoeologues. Here we report that--in wheat-rye hybrids where homologue...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms5580

    authors: Martín AC,Shaw P,Phillips D,Reader S,Moore G

    更新日期:2014-08-06 00:00:00

  • Taxonomic and functional diversity change is scale dependent.

    abstract::Estimates of recent biodiversity change remain inconsistent, debated, and infrequently assessed for their functional implications. Here, we report that spatial scale and type of biodiversity measurement influence evidence of temporal biodiversity change. We show a pervasive scale dependence of temporal trends in taxon...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-04889-z

    authors: Jarzyna MA,Jetz W

    更新日期:2018-07-02 00:00:00

  • Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study).

    abstract::Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. We hence conducted a randomized, double-blind, placebo-controlled trial with newly diagnosed T2D patie...

    journal_title:Nature communications

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41467-020-18414-8

    authors: Zhang Y,Gu Y,Ren H,Wang S,Zhong H,Zhao X,Ma J,Gu X,Xue Y,Huang S,Yang J,Chen L,Chen G,Qu S,Liang J,Qin L,Huang Q,Peng Y,Li Q,Wang X,Kong P,Hou G,Gao M,Shi Z,Li X,Qiu Y,Zou Y,Yang H,Wang J,Xu G,

    更新日期:2020-10-06 00:00:00

  • Human noise blindness drives suboptimal cognitive inference.

    abstract::Humans typically make near-optimal sensorimotor judgements but show systematic biases when making more cognitive judgements. Here we test the hypothesis that, while humans are sensitive to the noise present during early sensory encoding, the "optimality gap" arises because they are blind to noise introduced by later c...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-09330-7

    authors: Herce Castañón S,Moran R,Ding J,Egner T,Bang D,Summerfield C

    更新日期:2019-04-12 00:00:00

  • Rectified directional sensing in long-range cell migration.

    abstract::How spatial and temporal information are integrated to determine the direction of cell migration remains poorly understood. Here, by precise microfluidics emulation of dynamic chemoattractant waves, we demonstrate that, in Dictyostelium, directional movement as well as activation of small guanosine triphosphatase Ras ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms6367

    authors: Nakajima A,Ishihara S,Imoto D,Sawai S

    更新日期:2014-11-06 00:00:00

  • PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis.

    abstract::Mutations in patatin-like phospholipase domain-containing 1 (PNPLA1) cause autosomal recessive congenital ichthyosis, but the mechanism involved remains unclear. Here we show that PNPLA1, an enzyme expressed in differentiated keratinocytes, plays a crucial role in the biosynthesis of ω-O-acylceramide, a lipid componen...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms14609

    authors: Hirabayashi T,Anjo T,Kaneko A,Senoo Y,Shibata A,Takama H,Yokoyama K,Nishito Y,Ono T,Taya C,Muramatsu K,Fukami K,Muñoz-Garcia A,Brash AR,Ikeda K,Arita M,Akiyama M,Murakami M

    更新日期:2017-03-01 00:00:00

  • Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions.

    abstract::Iminium catalysis, involving the transformation of iminium ions to enamines, has been extensively studied in the context of a number of organic processes. However, the reverse of this process involving conversion of enamines to iminium species has not been realized. Here, we describe a new transformation-'oxidative en...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms1214

    authors: Zhang SL,Xie HX,Zhu J,Li H,Zhang XS,Li J,Wang W

    更新日期:2011-01-01 00:00:00

  • Exploiting a cognitive bias promotes cooperation in social dilemma experiments.

    abstract::The decoy effect is a cognitive bias documented in behavioural economics by which the presence of a third, (partly) inferior choice causes a significant shift in people's preference for other items. Here, we performed an experiment with human volunteers who played a variant of the repeated prisoner's dilemma game in w...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-05259-5

    authors: Wang Z,Jusup M,Shi L,Lee JH,Iwasa Y,Boccaletti S

    更新日期:2018-07-27 00:00:00

  • A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury.

    abstract::Renal tubular epithelial cells (RTECs) perform the essential function of maintaining the constancy of body fluid composition and volume. Toxic, inflammatory, or hypoxic-insults to RTECs can cause systemic fluid imbalance, electrolyte abnormalities and metabolic waste accumulation- manifesting as acute kidney injury (A...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-15638-6

    authors: Kim JY,Bai Y,Jayne LA,Hector RD,Persaud AK,Ong SS,Rojesh S,Raj R,Feng MJHH,Chung S,Cianciolo RE,Christman JW,Campbell MJ,Gardner DS,Baker SD,Sparreboom A,Govindarajan R,Singh H,Chen T,Poi M,Susztak K,Cobb SR,P

    更新日期:2020-04-21 00:00:00

  • Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones.

    abstract::A synthetic biology method based on heterologous biosynthesis coupled with genome mining is a promising approach for increasing the opportunities to rationally access natural product with novel structures and biological activities through total biosynthesis and combinatorial biosynthesis. Here, we demonstrate the adva...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-15664-4

    authors: Tsukada K,Shinki S,Kaneko A,Murakami K,Irie K,Murai M,Miyoshi H,Dan S,Kawaji K,Hayashi H,Kodama EN,Hori A,Salim E,Kuraishi T,Hirata N,Kanda Y,Asai T

    更新日期:2020-04-14 00:00:00

  • Three-dimensional strain dynamics govern the hysteresis in heterogeneous catalysis.

    abstract::Understanding catalysts strain dynamic behaviours is crucial for the development of cost-effective, efficient, stable and long-lasting catalysts. Here, we reveal in situ three-dimensional strain evolution of single gold nanocrystals during a catalytic CO oxidation reaction under operando conditions with coherent X-ray...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18622-2

    authors: Passos AR,Rochet A,Manente LM,Suzana AF,Harder R,Cha W,Meneau F

    更新日期:2020-09-18 00:00:00

  • The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.

    abstract::The insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) are highly related receptor tyrosine kinases with a disulfide-linked homodimeric architecture. Ligand binding to the receptor ectodomain triggers tyrosine autophosphorylation of the cytoplasmic domains, which stimulates catalytic activity and ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms7406

    authors: Cabail MZ,Li S,Lemmon E,Bowen ME,Hubbard SR,Miller WT

    更新日期:2015-03-11 00:00:00