Abstract:
:The mammalian vascular system consists of two distinct, but closely related, networks: the blood vasculature (itself divided into arterial and venous networks) and the lymphatic vasculature. EC (endothelial cell) lineage specification has been proposed to be determined during embryonic development, after which the ECs are committed to their fate. However, increasing evidence suggests that ECs retain various degrees of plasticity, and have the ability to express characteristics of alternative cell lineages. Therapeutic control of endothelial plasticity will allow greater understanding of the genesis and treatment of several vascular diseases.
journal_name
Biochem Soc Transjournal_title
Biochemical Society transactionsauthors
Cooley LS,Edwards DRdoi
10.1042/BST20110723subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1639-43issue
6eissn
0300-5127issn
1470-8752pii
BST20110723journal_volume
39pub_type
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
pub_type: 杂志文章,评审
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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更新日期:2008-12-01 00:00:00
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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更新日期:2000-12-01 00:00:00
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journal_title:Biochemical Society transactions
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journal_title:Biochemical Society transactions
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