Abstract：
:High blood pressure, or hypertension, is a very common disorder with a substantial impact on public health because of its associated complications. Despite the high prevalence of essential hypertension and years of research, the basic causes remain obscure. Here I review recent advances in understanding the pathophysiology of hypertension. I present a general overview of the field and, by necessity, use broad strokes to portray recent progress and place it in context. For this purpose, I use illustrative examples from the large number of important developments in hypertension research over the last five years. The intent of this review is to provide a sense of where the field is progressing, with an emphasis on work that sheds light on pathogenic mechanisms and that is therefore likely to inform new translational advances.
journal_name
Nat Medjournal_title
Nature medicineauthors
Coffman TMdoi
10.1038/nm.2541subject
Has Abstractpub_date
2011-11-07 00:00:00pages
1402-9issue
11eissn
1078-8956issn
1546-170Xpii
nm.2541journal_volume
17pub_type
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