Abstract:
:Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), non-volatile, direct metabolites of ethanol have been shown to be suitable markers for the evaluation of social and chronic excessive alcohol consumption. Previous investigations have shown that the regular use of hair-care products with high alcohol content lead to an increase of FAEE concentration and consequently gave false-positive results for the determination of FAEE in hair. In this study we investigated the influence of a long-term hair treatment with EtOH containing lotion, on the EtG concentrations in hair. In this study 7 volunteer subjects (classified as either rare, social or heavy drinkers) treated the right side of their scalp every day during a one or two month period with a commercial hair tonic (Seborin), which contains 44.0% ethanol (vol%). Collection of hair specimens from both sides of the scalp was done one day before hair treatment, one week and one month after treatment (for 5 subjects also after two months of treatment). A hair segment of 3 centimeters (cm) was cut and then washed with water and acetone, and then pulverized. EtG was quantified by GC/MS after pulverization and 2h of ultrasonication in water, extraction by solid phase extraction using Oasis MAX columns and derivatization with HFBA. Measurements were done in negative chemical ionization mode using EtG-D5 as internal standard. Comparison of EtG concentration in the treated and in the non-treated hair specimens did not show any increase at the different dates of collection for the 7 subjects. In conclusion, these results show that there is no indication for an increase of EtG after use of ethanol containing hair cosmetics.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Martins Ferreira L,Binz T,Yegles Mdoi
10.1016/j.forsciint.2011.10.015subject
Has Abstractpub_date
2012-05-10 00:00:00pages
123-5issue
1-3eissn
0379-0738issn
1872-6283pii
S0379-0738(11)00490-7journal_volume
218pub_type
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journal_title:Forensic science international
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pub_type: 历史文章,杂志文章
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.04.027
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pub_type: 杂志文章,评审
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journal_title:Forensic science international
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doi:10.1016/j.forsciint.2004.09.011
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.01.034
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.05.002
更新日期:2007-03-02 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:1990-11-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/s0379-0738(97)02137-3
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journal_title:Forensic science international
pub_type: 杂志文章
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.10.021
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journal_title:Forensic science international
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.12.018
更新日期:2009-03-10 00:00:00
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2005.02.036
更新日期:2006-04-20 00:00:00
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2012.04.018
更新日期:2012-09-10 00:00:00
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pub_type: 杂志文章
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.12.006
更新日期:2007-12-20 00:00:00
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.10.013
更新日期:2012-05-10 00:00:00