Abstract:
OBJECTIVE:To explore the changes in placental gene expression between women with preeclampsia and those with superimposed preeclampsia on chronic hypertension. MATERIALS AND METHODS:In Taiwanese population, we compared gene expression between the placentas from preeclamptic patients and those with superimposed preeclampsia on chronic hypertension. RESULTS:Although top-ranked activated genes between preeclampsia and superimposed preeclampsia on chronic hypertension were different, functional network analyses indicate that these genes are mainly involved in the regulation of cell death and apoptosis. These results suggest that apoptosis and other types of cell death in the placenta are common consequences of both diseases. However, placental endoglin (ENG) was expressed at a significantly higher level in preeclampsia than in superimposed preeclampsia. Results of functional network analysis indicated that ENG may play a role in the pathogenesis of preeclampsia through its interference with the endothelial nitric oxide synthase-regulated vasodilation. CONCLUSION:Our results support the fact that ENG is the culprit for the development of preeclampsia. In addition, this study identifies several other genes in the placenta, which are transcriptionally regulated in pregnancy-related hypertensions.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Chang SD,Chao AS,Peng HH,Chang YL,Wang CN,Cheng PJ,Lee YS,Chao A,Wang THdoi
10.1016/j.tjog.2011.07.005subject
Has Abstractpub_date
2011-09-01 00:00:00pages
283-91issue
3eissn
1028-4559issn
1875-6263pii
S1028-4559(11)00126-4journal_volume
50pub_type
杂志文章abstract:OBJECTIVE:To estimate the prevalence of nocturia in Taiwanese women aged 20-59 years. MATERIALS AND METHODS:A random sample of 4,549 women within the age range was selected by a multistage sampling design. Face-to-face visits with 3,537 women were completed by well-trained professional interviewers. Nocturia, accordin...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(08)60107-2
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:Human papillomavirus (HPV) has been recognized as the major etiologic agent of cervical squamous cell carcinoma. However, it has been demonstrated that HPV infection is usually a self-limited process and does not lead to significant epithelial lesions or cancer. Recent data indicate that persistent high-risk ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.06.001
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:We present detection of paternal origin of fetal trisomy 21 in a pregnancy with isolated ventriculomegaly but without advanced parental age. CASE REPORT:A 29-year-old pregnant woman was admitted to the hospital at 18 weeks of gestation for tocolytic treatment because of irregular uterine contractions. Her hu...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type:
doi:10.1016/j.tjog.2020.05.025
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:Pregnancy-associated death is defined by the American College of Obstetricians and Gynecologists as "a death of a woman while pregnant or within 1 year of termination of pregnancy, irrespective of the cause of death." We sought to determine pregnancy-associated mortality ratio (PAMR) in Taiwan and to compare ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.007
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Currently, Taiwan's Artificial Reproduction Act denies the legality of practicing surrogacy in Taiwan. The fact that numerous intended parents access surrogacy through fertility tourism or illegal practice leads to various types of disputes. This article illustrates the types of surrogacy-related disputes in ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.06.006
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the concurrent interaction of laparoscopic and robotic-assisted surgery in the initial learning period of endometrial cancer staging. MATERIALS AND METHODS:A retrospective cohort study was performed for the first 44 consecutive patients with endometrial cancer underwent laparoscopic (LSS) or robo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.10.014
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:We describe our experience with serial uterine artery embolization (UAE) combined with standard weekly methotrexate and a eight-day methotrexate/folinic acid (MTX/FA) treatment regimen in the management of placenta accreta spectrum (PAS) disorder at 7 weeks of gestation. CASE REPORT:A 38-year-old woman, grav...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type:
doi:10.1016/j.tjog.2020.09.027
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Patients with Long QT syndrome (LQTS) P may present with torsades de pointes, ventricular tachycardia (VT), or ventricular fibrillation (VF) and are at risk of sudden cardiac death. MATERIALS AND METHODS:A 38 y/o female patient with uterus myoma developed VF during laparoscopic assisted vaginal hysterectomy ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2019.05.031
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:Sea buckthorn (Hippophae rhamnoides L.) and St. John's wort (Hypericum perforatum L.) are used as an emmenagog and for the treatment of other gynecological disorders including uterus inflammation and endometriosis. The aim of the present study is to investigate the potential of a mixture of sea buckthorn and ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.01.006
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the risk of birth weights over 4000 g (macrosomia) in association with following the 2009 American Institute of Medicine (AIOM) recommendations. MATERIALS AND METHODS:Seventy-six nondiabetic women who delivered a singleton, term macrosomic fetus and 82 women who delivered a si...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.05.001
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestation. MATERIALS AND METHODS:From 2006 to 2007, we recruited 150 pregnant wo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/S1028-4559(09)60269-2
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:Longitudinal data on bone decline in ethnic Chinese elderly are sparse, especially in healthy, aged women. This study reviews the longitudinal change in bone mineral density (BMD) at the femoral neck, great trochanter, and Ward's triangle in healthy elderly Taiwanese women. MATERIALS AND METHODS:A prospectiv...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2012.08.001
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Mucinous ovarian carcinoma (MOC) is an uncommon subtype of epithelial ovarian cancers, and the pathogenesis is still poorly understood because of its rarity. We conducted a gene set-based analysis to investigate the pathogenesis of MOC by integrating microarray gene expression datasets based on the regularity...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.12.016
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the demographics, clinical presentations, laboratory findings, and maternal and fetal outcomes in patients with acute fatty liver of pregnancy. MATERIALS AND METHODS:A retrospective review was conducted of the records of pregnant patients with a diagnosis of acute fatty liver in a tertiary medica...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(10)60033-2
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:This study aims to identify the prevalence of bacterial vaginosis (BV) and cervicitis among 511 female workers attending gynecological examination and determine the risk factors for bacterial vaginosis and cervicitis. MATERIALS AND METHODS:This study enrolled 511 female workers attending gynecological examin...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.11.036
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:Primary small cell carcinoma of the endometrium is a rare disease that can only be diagnosed at an advanced stage, and thus has a poor prognosis. In this study, the clinicopathologic characteristics of endometrial small cell carcinoma are described and the survival outcomes are discussed. MATERIALS AND METH...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.05.006
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:Many women quit smoking during pregnancy resume in postpartum period and difficult to prevent. No studies had focused on their psychosocial response in Taiwan. We analyzed data from a trial of Taiwan Smoker's Helpline (TSH) to determine factors associated with smoking relapse after delivery. MATERIALS AND ME...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.tjog.2019.07.015
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:Loeys-Dietz syndrome (LDS) is associated with a higher risk of aortic dissections (ADs) during pregnancy and postpartum. However, there is limited evidence about the perinatal management of LDS patients who have undergone prophylactic aortic root replacements (ARRs) before conception. CASE REPORT:We present ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type:
doi:10.1016/j.tjog.2020.10.005
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:We describe a case of gestational choriocarcinoma metastasized to the kidney and lung, which presented initially as refractory hematuria after a term pregnancy 5 years earlier. CASE REPORT:A 35-year-old woman, G2P1, with a previous history of full-term pregnancy in 2009, presented to the emergency department...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.08.028
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:Although uterine didelphys per se is not associated with an impaired ability to conceive, the association between uterine anomalies and gestational trophoblastic neoplasia (GTN) remains unclear. The management of chemotherapy-resistant GTN in women with uterine didelphys raises a new issue regarding whether t...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.02.024
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of carbetocin and oxytocin on hemorrhage-related changes in women with cesarean deliveries (CS) for different indications. MATERIALS AND METHODS:A retrospective cohort study was conducted on 1568 women with CS before labor onset (elective CS, n = 1153) or during labor (intrapartum CS,...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.08.011
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this methodology study is to examine the relative validity of four dietary assessment methods during pregnancy and to understand the pros and cons of each method. MATERIALS AND METHODS:We recruited 181 healthy pregnant women with less than 20 weeks of gestation and collected information throug...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.04.007
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:Postpartum hemorrhage remains the leading cause of maternal mortality in developing countries and a significant proportion of these cases are attributable to uterine atony. In contrast to the advances made in the treatment of postpartum hemorrhage, there has been few novel prophylactic agents. This study was ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,meta分析
doi:10.1016/j.tjog.2018.04.002
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe our experience with the diagnosis and management of acquired uterine vascular abnormalities associated with persistent human chorionic gonadotropin (hCG). Through this case series, we sought to establish our protocol for the treatment and follow-up of uterine vascular les...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.06.008
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:This study aims to validate the BACs-on-Beads (BoB) technology as a robust and high throughput method for pre-implantation genetic screening (PGS) for aneuploidy. MATERIAL AND METHODS:The performances with respect to the sensitivity, specificity, success rate and detection rate of this technique from new BoB...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.01.011
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To examine the association of antenatal renal pelvic dilatation observed on midtrimester ultrasound screening with the presence of hydronephrosis in newborn infants. MATERIALS AND METHODS:The records of patients who received fetal ultrasound examination at 18-28 weeks' gestation from May 2008 to March 2012 w...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.08.007
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To assess the long-term outcomes of laparoscopic staging surgery (LSS) in treating patients with endometrial carcinoma. MATERIALS AND METHODS:Patients with endometrial cancer who underwent LSS between June 1995 and June 2014 were prospectively registered. Perioperative data, complications, disease recurrence...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.035
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the usefulness of ultrasound in pregnancies with a positive non-invasive prenatal testing (NIPT) result for trisomy 18/13. MATERIALS AND METHODS:During a four-year period, the pregnant women who were referred for invasive genetic testing because of positive NIPT results ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.tjog.2019.09.012
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:We present a case of type I diastematomyelia diagnosed with ultrasonography at the 14th week of gestation. CASE REPORT:A 26-year-old primigravida at 14 weeks' gestation was presented to our outpatient department with a complaint of dysuria. Routine antenatal ultrasound revealed disruption of the fetal upper ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60279-5
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to summarize the experience on prenatal diagnosis of Down syndrome. MATERIALS AND METHODS:The study includes a retrospective data analysis of 157 prenatally detected cases of Down syndrome, routinely diagnosed among 6448 prenatal investigations performed during a 13-year period (2002...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.10.004
更新日期:2017-12-01 00:00:00