Auditory processing deficits in individuals with primary open-angle glaucoma.

Abstract:

OBJECTIVE:The high energy demand of the auditory and visual pathways render these sensory systems prone to diseases that impair mitochondrial function. Primary open-angle glaucoma, a neurodegenerative disease of the optic nerve, has recently been associated with a spectrum of mitochondrial abnormalities. This study sought to investigate auditory processing in individuals with open-angle glaucoma. DESIGN/STUDY SAMPLE: Twenty-seven subjects with open-angle glaucoma underwent electrophysiologic (auditory brainstem response), auditory temporal processing (amplitude modulation detection), and speech perception (monosyllabic words in quiet and background noise) assessment in each ear. A cohort of age, gender and hearing level matched control subjects was also tested. RESULTS:While the majority of glaucoma subjects in this study demonstrated normal auditory function, there were a significant number (6/27 subjects, 22%) who showed abnormal auditory brainstem responses and impaired auditory perception in one or both ears. CONCLUSIONS:The finding that a significant proportion of subjects with open-angle glaucoma presented with auditory dysfunction provides evidence of systemic neuronal susceptibility. Affected individuals may suffer significant communication difficulties in everyday listening situations.

journal_name

Int J Audiol

authors

Rance G,O'Hare F,O'Leary S,Starr A,Ly A,Cheng B,Tomlin D,Graydon K,Chisari D,Trounce I,Crowston J

doi

10.3109/14992027.2011.609185

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

10-5

issue

1

eissn

1499-2027

issn

1708-8186

journal_volume

51

pub_type

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