Abstract:
:Laccases (p-diphenol oxidase, EC 1.10.3.2) are blue multicopper oxidases that catalyze the reduction of dioxygen to water, with a concomitant oxidation of small organic substrates. Since the description at the end of the nineteenth century of a factor catalyzing the rapid hardening of the latex of the Japanese lacquer trees (Rhus sp.) exposed to air laccases from different origins (plants, fungi bacteria) have been continuously discovered and extensively studied. Nowadays, molecular evolution and other powerful protein modification techniques offer possibilities to develop tailored laccases for a wide array of applications including drug synthesis, biosensors or biofuel cells. Here, we give an overview on strategies and results of our laboratory in the design of new biocatalysts based on laccases.
journal_name
Curr Genomicsjournal_title
Current genomicsauthors
Robert V,Mekmouche Y,Pailley PR,Tron Tdoi
10.2174/138920211795564340subject
Has Abstractpub_date
2011-04-01 00:00:00pages
123-9issue
2eissn
1389-2029issn
1875-5488pii
CG-12-123journal_volume
12pub_type
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