Abstract:
OBJECTIVE:Hemodialysis (HD) patients are at risk of deficiency of essential trace elements and excess of toxic trace elements. The aim of the study was to evaluate the relation between the serum levels of some trace elements and heavy metals (iron, zinc, manganese, copper, magnesium, cobalt, cadmium, and lead) and endothelial function in HD patients. METHODS:Forty-eight chronic HD patients without known atherosclerotic disease and 42 age- and sex-matched healthy individuals were included in the study. The serum levels of trace elements (iron, zinc, manganese, copper, and magnesium) and heavy metals (cobalt, cadmium, and lead) were measured by Atomic Adsorption Spectrophotometer (UNICAM-929). RESULTS:The serum levels of iron, zinc, and manganese were lower, and levels of copper, magnesium, cobalt, cadmium, and lead were higher in HD patients compared to controls. Flow-mediated dilatation (FMD %) in HD patients was lower than that in the control group (7.27 ± 0.76 vs. 11.29 ± 0.82, P < 0.001). There was a significant negative correlation between FMD % and serum levels of cobalt (r = -0.313, P = 0.03) and cadmium (r = -0.524, P < 0.01). A linear regression analysis showed that serum cadmium levels were still significantly and negatively correlated with FMD % (regression coefficient = -0.526, P < 0.001). CONCLUSION:We first demonstrated that serum cadmium levels independently predict endothelial function in HD patients without known atherosclerotic disease.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Kaya Y,Ari E,Demir H,Gecit I,Beytur A,Kaspar Cdoi
10.1007/s11255-011-0055-2subject
Has Abstractpub_date
2012-10-01 00:00:00pages
1487-92issue
5eissn
0301-1623issn
1573-2584journal_volume
44pub_type
杂志文章abstract::Minimal change disease is the most common glomerular disease affecting children; its prevalence among adults, however, is eclipsed by other glomerular pathologies. Each of these diseases has a number of classic associations, such as membranoproliferative glomerulonephritis with hepatitis C. We report the case of a mid...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0285-y
更新日期:2013-12-01 00:00:00
abstract::Twenty-six boys were evaluated and treated for posterior urethral valves. At the time the valves were diagnosed unilateral or bilateral vesicoureteral reflux was present in 58% of the ureters and 69% of the children, while dilatation of the upper urinary tract was present in 88% and 92%, respectively. There was a vari...
journal_title:International urology and nephrology
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
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abstract:PURPOSE:Type 2 diabetes mellitus (T2DM) patients treated with metformin are predisposed to develop contrast-induced nephropathy (CIN) after received emergency contrast-enhanced computed tomography (CT) examination. We evaluated the protective effects of alprostadil on CIN in T2DM patients treated with metformin after c...
journal_title:International urology and nephrology
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abstract:PURPOSE:To perform a systematic review and meta-analysis to evaluate the cardiovascular prevention effect of aspirin among patients with chronic kidney disease (CKD). METHODS:A comprehensive literature search was conducted in Embase, PubMed, and Cochrane library (up to March 2019) without language limitations. Randomi...
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abstract::The long-term results of microsurgical shunts for idiopathic varicocele are reported in the present paper. Sixty-two patients with a total of 65 varicoceles (three were bilateral) were followed up for 1 to 8 years. Pre- and postoperative ultrasonographic evaluation of varicocele size was considered of great importance...
journal_title:International urology and nephrology
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
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pub_type: 杂志文章,meta分析
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0288-8
更新日期:2013-06-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
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更新日期:2014-12-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:1989-01-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:International urology and nephrology
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更新日期:2010-09-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:1991-01-01 00:00:00
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更新日期:2020-09-28 00:00:00
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journal_title:International urology and nephrology
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