Abstract:
:Several 2,5-disubstituted-1,3,4-oxadiazoles (4a-f) and 3,6-disubstituted-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles (7a-f) were synthesized and characterized by elemental analyses and spectral data. These compounds were screened for their anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation activities. Compound 7c showed excellent anti-inflammatory and remarkable analgesic activity with reduced ulcerogenic and lipid peroxidation activity when compared with ibuprofen.
journal_name
J Enzyme Inhib Med Chemjournal_title
Journal of enzyme inhibition and medicinal chemistryauthors
Chawla G,Kumar U,Bawa S,Kumar Jdoi
10.3109/14756366.2011.606543subject
Has Abstractpub_date
2012-10-01 00:00:00pages
658-65issue
5eissn
1475-6366issn
1475-6374journal_volume
27pub_type
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