Componential Granger causality, and its application to identifying the source and mechanisms of the top-down biased activation that controls attention to affective vs sensory processing.

Abstract:

:We describe a new measure of Granger causality, componential Granger causality, and show how it can be applied to the identification of the directionality of influences between brain areas with functional neuroimaging data. Componential Granger causality measures the effect of y on x, but allows interaction effects between y and x to be measured. In addition, the terms in componential Granger causality sum to 1, allowing causal effects to be directly compared between systems. We show using componential Granger causality analysis applied to an fMRI investigation that there is a top-down attentional effect from the anterior dorsolateral prefrontal cortex to the orbitofrontal cortex when attention is paid to the pleasantness of a taste, and that this effect depends on the activity in the orbitofrontal cortex as shown by the interaction term. Correspondingly there is a top-down attentional effect from the posterior dorsolateral prefrontal cortex to the insular primary taste cortex when attention is paid to the intensity of a taste, and this effect depends on the activity of the insular primary taste cortex as shown by the interaction term. Componential Granger causality thus not only can reveal the directionality of effects between areas (and these can be bidirectional), but also allows the mechanisms to be understood in terms of whether the causal influence of one system on another depends on the state of the system being causally influenced. Componential Granger causality measures the full effects of second order statistics by including variance and covariance effects between each time series, thus allowing interaction effects to be measured, and also provides a systematic framework within which to measure the effects of cross, self, and noise contributions to causality. The findings reveal some of the mechanisms involved in a biased activation theory of selective attention.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Ge T,Feng J,Grabenhorst F,Rolls ET

doi

10.1016/j.neuroimage.2011.08.047

subject

Has Abstract

pub_date

2012-01-16 00:00:00

pages

1846-58

issue

2

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(11)00964-5

journal_volume

59

pub_type

杂志文章
  • Task-dependent modulation of the visual sensory thalamus assists visual-speech recognition.

    abstract::The cerebral cortex modulates early sensory processing via feed-back connections to sensory pathway nuclei. The functions of this top-down modulation for human behavior are poorly understood. Here, we show that top-down modulation of the visual sensory thalamus (the lateral geniculate body, LGN) is involved in visual-...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2018.05.032

    authors: Díaz B,Blank H,von Kriegstein K

    更新日期:2018-09-01 00:00:00

  • Visual deviant stimuli produce mismatch responses in the amplitude dynamics of neuronal oscillations.

    abstract:OBJECTIVES:Auditory and visual deviant stimuli evoke mismatch negativity (MMN) responses, which can be recorded with electroencephalography (EEG) and magnetoencephalography (MEG). However, little is known about the role of neuronal oscillations in encoding of rare stimuli. We aimed at verifying the existence of a mecha...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2016.07.024

    authors: Tugin S,Hernandez-Pavon JC,Ilmoniemi RJ,Nikulin VV

    更新日期:2016-11-15 00:00:00

  • Source stability index: a novel beamforming based localisation metric.

    abstract::Many experimental studies into human brain function now use magnetoencephalography (MEG) to non-invasively investigate human neuronal activity. A number of different analysis techniques use the observed magnetic fields outside of the head to estimate the location and strength of the underlying neural generators. One s...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2009.09.055

    authors: Hymers M,Prendergast G,Johnson SR,Green GG

    更新日期:2010-01-15 00:00:00

  • Resting state functional connectivity reflects abnormal task-activated patterns in a developmental object agnosic.

    abstract::Even in the absence of stimulation or task, the cerebral cortex shows an incessant pattern of ultra slow fluctuations which are coherent across brain regions. In the healthy brain these coherent patterns (also termed resting state functional connectivity) often exhibit spatial similarity to the large scale organizatio...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2012.12.049

    authors: Gilaie-Dotan S,Hahamy-Dubossarsky A,Nir Y,Berkovich-Ohana A,Bentin S,Malach R

    更新日期:2013-04-15 00:00:00

  • High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T.

    abstract::Locus Coeruleus (LC) is a neuromelanin-rich brainstem structure that is the source of noradrenaline in the cortex and is thought to modulate attention and memory. LC imaging in vivo is commonly performed with a 2D T1-weighted Turbo Spin Echo (TSE) MRI sequence, an approach that suffers from several drawbacks at 3T, in...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.07.045

    authors: Priovoulos N,Jacobs HIL,Ivanov D,Uludağ K,Verhey FRJ,Poser BA

    更新日期:2018-03-01 00:00:00

  • Changes of individual BrainAGE during the course of the menstrual cycle.

    abstract::Brain morphology varies during the course of the menstrual cycle, with increases in individual gray matter volume at the time of ovulation. This study implemented our previously presented BrainAGE framework to analyze short-term neuroanatomical changes in healthy young women due to hormonal changes during the menstrua...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.04.036

    authors: Franke K,Hagemann G,Schleussner E,Gaser C

    更新日期:2015-07-15 00:00:00

  • The missing link: analogous human and primate cortical gamma oscillations.

    abstract::Recent animal studies highlighting the relationship between functional imaging signals and the underlying neuronal activity have revealed the potential capabilities of non-invasive methods. However, the valuable exchange of information between animal and human studies remains restricted by the limited evidence of dire...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.neuroimage.2005.01.009

    authors: Hall SD,Holliday IE,Hillebrand A,Singh KD,Furlong PL,Hadjipapas A,Barnes GR

    更新日期:2005-05-15 00:00:00

  • Role of the human retrosplenial cortex/parieto-occipital sulcus in perspective priming.

    abstract::The ability to imagine the world from a different viewpoint is a fundamental competence for spatial reorientation and for imagining what another individual sees in the environment. Here, we investigated the neural bases of such an ability using functional magnetic resonance imaging. Healthy participants detected targe...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.10.040

    authors: Sulpizio V,Committeri G,Lambrey S,Berthoz A,Galati G

    更新日期:2016-01-15 00:00:00

  • Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths.

    abstract::Breathing rate and depth influence the concentration of carbon dioxide in the blood, altering cerebral blood flow and thus functional magnetic resonance imaging (fMRI) signals. Such respiratory fluctuations can have substantial influence in studies of fMRI signal covariance in subjects at rest, the so-called "resting ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2019.116234

    authors: Power JD,Lynch CJ,Dubin MJ,Silver BM,Martin A,Jones RM

    更新日期:2020-01-01 00:00:00

  • Structural and functional neuroplasticity in human learning of spatial routes.

    abstract::Recent findings with both animals and humans suggest that decreases in microscopic movements of water in the hippocampus reflect short-term neuroplasticity resulting from learning. Here we examine whether such neuroplastic structural changes concurrently alter the functional connectivity between hippocampus and other ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.10.015

    authors: Keller TA,Just MA

    更新日期:2016-01-15 00:00:00

  • Cerebral correlates of motor imagery of normal and precision gait.

    abstract::We have examined the cerebral structures involved in motor imagery of normal and precision gait (i.e., gait requiring precise foot placement and increased postural control). We recorded cerebral activity with functional magnetic resonance imaging while subjects imagined walking along paths of two different widths (bro...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2008.03.020

    authors: Bakker M,De Lange FP,Helmich RC,Scheeringa R,Bloem BR,Toni I

    更新日期:2008-07-01 00:00:00

  • Improved determination of the myelin water fraction in human brain using magnetic resonance imaging through Bayesian analysis of mcDESPOT.

    abstract::Myelin water fraction (MWF) mapping with magnetic resonance imaging has led to the ability to directly observe myelination and demyelination in both the developing brain and in disease. Multicomponent driven equilibrium single pulse observation of T1 and T2 (mcDESPOT) has been proposed as a rapid approach for multicom...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.10.034

    authors: Bouhrara M,Spencer RG

    更新日期:2016-02-15 00:00:00

  • Automatic segmentation of the striatum and globus pallidus using MIST: Multimodal Image Segmentation Tool.

    abstract::Accurate segmentation of the subcortical structures is frequently required in neuroimaging studies. Most existing methods use only a T1-weighted MRI volume to segment all supported structures and usually rely on a database of training data. We propose a new method that can use multiple image modalities simultaneously ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.10.013

    authors: Visser E,Keuken MC,Douaud G,Gaura V,Bachoud-Levi AC,Remy P,Forstmann BU,Jenkinson M

    更新日期:2016-01-15 00:00:00

  • Quantitative comparison of functional magnetic resonance imaging with positron emission tomography using a force-related paradigm.

    abstract::The intention of our study was to compare functional magnetic resonance imaging (fMRI) with positron emission tomography (PET). We used the same force-related motor paradigm for both techniques, which allows for quantification of stimulus intensity. Regional cerebral blood flow (rCBF) was determined with PET in six ma...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1996.0071

    authors: Dettmers C,Connelly A,Stephan KM,Turner R,Friston KJ,Frackowiak RS,Gadian DG

    更新日期:1996-12-01 00:00:00

  • Functional MRI with variable echo time acquisition.

    abstract::A new functional MRI protocol that integrates variable echo time (TE) acquisition and a block-design paradigm is proposed and evaluated with finger-tapping motor task. Simulations and experimental data show that the blood oxygenation level-dependent (BOLD) sensitivity achieved with this approach is comparable to that ...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.neuroimage.2003.08.013

    authors: Chen NK,Egorova S,Guttmann CR,Panych LP

    更新日期:2003-12-01 00:00:00

  • Age-related trends in neuromagnetic transient beta burst characteristics during a sensorimotor task and rest in the Cam-CAN open-access dataset.

    abstract::Non-invasive neurophysiological recordings, such as those measured by magnetoencelography (MEG), provide insight into the behaviour of neural networks and how these networks change with factors such as task performance, disease state, and age. Recently, there has been a trend in describing neurophysiological recording...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2020.117245

    authors: Brady B,Power L,Bardouille T

    更新日期:2020-11-15 00:00:00

  • Macroscale variation in resting-state neuronal activity and connectivity assessed by simultaneous calcium imaging, hemodynamic imaging and electrophysiology.

    abstract::Functional imaging of spontaneous activity continues to play an important role in the field of connectomics. The most common imaging signal used for these experiments is the blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) signal, but how this signal relates to spontaneous neuronal activity remains incomplete...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.12.070

    authors: Murphy MC,Chan KC,Kim SG,Vazquez AL

    更新日期:2018-04-01 00:00:00

  • Cortical hemodynamic changes during the Trier Social Stress Test: An fNIRS study.

    abstract::The study of the stress response has been of great interest in the last decades due to its relationship to physical and mental health. Along with the technological progress in the neurosciences, different methods of stress induction have been developed for the special requirements regarding the acquisition of neuroima...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.12.061

    authors: Rosenbaum D,Hilsendegen P,Thomas M,Haeussinger FB,Metzger FG,Nuerk HC,Fallgatter AJ,Nieratschker V,Ehlis AC

    更新日期:2018-05-01 00:00:00

  • Color responses and their adaptation in human superior colliculus and lateral geniculate nucleus.

    abstract::We use an fMRI adaptation paradigm to explore the selectivity of human responses in the lateral geniculate nucleus (LGN) and superior colliculus (SC) to red-green color and achromatic contrast. We measured responses to red-green (RG) and achromatic (ACH) high contrast sinewave counter-phasing rings with and without ad...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2016.04.067

    authors: Chang DHF,Hess RF,Mullen KT

    更新日期:2016-09-01 00:00:00

  • White matter alterations to cingulum and fornix following very preterm birth and their relationship with cognitive functions.

    abstract::Very preterm birth (VPT; <32 weeks of gestation) has been associated with impairments in memory abilities and functional neuroanatomical brain alterations in medial temporal and fronto-parietal areas. Here we investigated the relationship between structural connectivity in memory-related tracts and various aspects of ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.02.026

    authors: Caldinelli C,Froudist-Walsh S,Karolis V,Tseng CE,Allin MP,Walshe M,Cuddy M,Murray RM,Nosarti C

    更新日期:2017-04-15 00:00:00

  • Emotional arousal impairs association-memory: Roles of amygdala and hippocampus.

    abstract::Emotional arousal is well-known to enhance memory for individual items or events, whereas it can impair association memory. The neural mechanism of this association memory impairment by emotion is not known: In response to emotionally arousing information, amygdala activity may interfere with hippocampal associative e...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.04.065

    authors: Madan CR,Fujiwara E,Caplan JB,Sommer T

    更新日期:2017-08-01 00:00:00

  • Nocebo-induced modulation of cerebral itch processing - An fMRI study.

    abstract::It has been shown repeatedly that perceiving itch-related pictures or listening to a lecture on itch can enhance itch sensation and scratching behaviour (Niemeier and Gieler, 2000; Holle et al., 2012; Lloyd et al., 2013), indicating that itch is strongly influenced by expectations. Using fMRI, we investigated the neur...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.10.056

    authors: van de Sand MF,Menz MM,Sprenger C,Büchel C

    更新日期:2018-02-01 00:00:00

  • The preparation and readiness for voluntary movement: a high-field event-related fMRI study of the Bereitschafts-BOLD response.

    abstract::Activity within motor areas of the cortex begins to increase 1 to 2 s prior to voluntary self-initiated movement (termed the Bereitschaftspotential or readiness potential). There has been much speculation and debate over the precise source of this early premovement activity as it is important for understanding the rol...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1016/s1053-8119(03)00291-x

    authors: Cunnington R,Windischberger C,Deecke L,Moser E

    更新日期:2003-09-01 00:00:00

  • Offset analgesia is mediated by activation in the region of the periaqueductal grey and rostral ventromedial medulla.

    abstract::Interrupting a continuous noxious heat by a greater noxious heat causes rapid and disproportionate pain reduction when the original noxious heat returns. This reduction in pain experience, known as offset analgesia, is believed to be the consequence of active descending inhibitory control of pain originating in the pe...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2009.04.032

    authors: Derbyshire SW,Osborn J

    更新日期:2009-09-01 00:00:00

  • Abnormal cortical processing of pattern motion in amblyopia: evidence from fMRI.

    abstract::Converging evidence from human psychophysics and animal neurophysiology indicates that amblyopia is associated with abnormal function of area MT, a motion sensitive region of the extrastriate visual cortex. In this context, the recent finding that amblyopic eyes mediate normal perception of dynamic plaid stimuli was s...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2012.01.078

    authors: Thompson B,Villeneuve MY,Casanova C,Hess RF

    更新日期:2012-04-02 00:00:00

  • Depression in Parkinson's disease: convergence from voxel-based morphometry and functional magnetic resonance imaging in the limbic thalamus.

    abstract::Depression is the most frequent psychiatric disorder in Parkinson's disease (PD). Although evidence suggests that depression in PD is related to the degenerative process that underlies the disease, further studies are necessary to better understand the neural basis of depression in this population of patients. In orde...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2009.04.059

    authors: Cardoso EF,Maia FM,Fregni F,Myczkowski ML,Melo LM,Sato JR,Marcolin MA,Rigonatti SP,Cruz AC Jr,Barbosa ER,Amaro E Jr

    更新日期:2009-08-15 00:00:00

  • Cingulate cortex function and multi-modal connectivity mapped using intracranial stimulation.

    abstract::The cingulate cortex is part of the limbic system. Its function and connectivity are organized in a rostro-caudal and ventral-dorsal manner which was addressed by various other studies using rather coarse cortical parcellations. In this study, we aim at describing its function and connectivity using invasive recording...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2020.117059

    authors: Oane I,Barborica A,Chetan F,Donos C,Maliia MD,Arbune AA,Daneasa A,Pistol C,Nica AE,Bajenaru OA,Mindruta I

    更新日期:2020-10-15 00:00:00

  • Estimating cortical column sensory networks in rodents from micro-electrocorticograph (μECoG) recordings.

    abstract::Micro-electrocorticograph (μECoG) arrays offer the flexibility to record local field potentials (LFPs) from the surface of the cortex, using high density electrodes that are sub-mm in diameter. Research to date has not provided conclusive evidence for the underlying signal generation of μECoG recorded LFPs, or if μECo...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.09.043

    authors: Pizarro R,Richner T,Brodnick S,Thongpang S,Williams J,Van Veen B

    更新日期:2017-12-01 00:00:00

  • Coupling between visual alpha oscillations and default mode activity.

    abstract::Although, on average, the magnitude of alpha oscillations (8 to 12 Hz) is decreased in task-relevant cortices during externally oriented attention, its fluctuations have significant consequences, with increased level of alpha associated with decreased level of visual processing and poorer behavioral performance. Funct...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2012.11.058

    authors: Mo J,Liu Y,Huang H,Ding M

    更新日期:2013-03-01 00:00:00

  • Relationship between aberrant brain connectivity and clinical features in Angelman Syndrome: a new method using tract based spatial statistics of DTI color-coded orientation maps.

    abstract:AIM:In order to relate brain structural abnormalities to clinical features of Angelman Syndrome (AS), we determined the locations of abnormal regional white matter architecture in AS children using a sensitive and objective whole brain approach to analyze diffusion tensor imaging (DTI) color-coded orientation maps. ME...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2011.07.067

    authors: Tiwari VN,Jeong JW,Wilson BJ,Behen ME,Chugani HT,Sundaram SK

    更新日期:2012-01-02 00:00:00