Comparative evaluation of propolis and triantibiotic mixture as an intracanal medicament against Enterococcus faecalis.

Abstract:

INTRODUCTION:The aim of this study was to evaluate and compare the antimicrobial activity of calcium hydroxide, triantibiotic mixture (TAM), and an ethanol extract of propolis as intracanal medicaments on Enterococcus faecalis-infected root canals. METHODS:One hundred twenty extracted intact human permanent incisors were decoronated, and chemomechanical preparation of the root canal was performed. After sterilization of the samples, they were inoculated with pure culture of E. faecalis and incubated. After incubation, colony-forming units were recorded before medication. Then, samples were divided randomly into five groups (n = 24). Each group was then exposed to various intracanal medicaments, namely calcium hydroxide (group 1), TAM (group 2), propolis (group 3), ethanol (group 4), and saline as the control group (group V). The antibacterial effectiveness of the different intracanal medicament was recorded by determining the percentage reduction in colony counts (%RCC) at the end of days 1, 2, and 7. The data were statistically analyzed using one-way analysis of variance and Tukey Honestly Significant Difference (HSD) post hoc test. RESULTS:The %RCC was highest for propolis showing 100% reduction on day 2 followed by TAM showing 82.5%, 92.2%, and 98.4% of reduction on days 1, 2, and 3, respectively. Calcium hydroxide showed a gradual increase in antibacterial activity with a maximum of 59.4% on day 7. CONCLUSIONS:Propolis was more effective than TAM against E. faecalis at a 2-day time period, and both were equally effective at 7 days.

journal_name

J Endod

journal_title

Journal of endodontics

authors

Madhubala MM,Srinivasan N,Ahamed S

doi

10.1016/j.joen.2011.05.028

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

1287-9

issue

9

eissn

0099-2399

issn

1878-3554

pii

S0099-2399(11)00659-5

journal_volume

37

pub_type

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