Abstract:
:Men with Down syndrome are considered as infertile although the causes of infertility are not known in detail yet. Although this constitutes a general rule there are three confirmed cases of parenting by fathers with Down syndrome. Many investigators have addressed the causes of infertility and their studies indicate that the causes may be hormonal deficits, morphological alterations of the gonads, abnormal spermatogenesis, psychological and social factors related to the mental retardation. It is obvious that the extra chromosome 21 has a detrimental direct and indirect effect on the reproductive capacity of the affected male patient. But the definite cause of the insufficient and inadequate spermatogenesis remains to be discovered.
journal_name
Andrologiajournal_title
Andrologiaauthors
Stefanidis K,Belitsos P,Fotinos A,Makris N,Loutradis D,Antsaklis Adoi
10.1111/j.1439-0272.2010.01043.xsubject
Has Abstractpub_date
2011-10-01 00:00:00pages
353-7issue
5eissn
0303-4569issn
1439-0272journal_volume
43pub_type
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