Abstract:
:The human colonic microbiota degrades dietary substrates that are indigestible in the upper GIT (gastrointestinal tract), releasing bacterial metabolites, some of which are important for gut health. Advances in molecular biology techniques have facilitated detailed analyses of the composition of the bacterial community resident in the lower GIT. Such analyses have indicated that more than 500 different bacterial species colonize an individual, and that, although there is much functional consistency in the resident bacterial groups, there is considerable inter-individual variation at the species/strain level. The bacterial community develops during early childhood until it reaches an adult-like composition. Whereas colonization and host factors influence the species composition, dietary factors also have an important impact, with specific bacterial groups changing in response to specific dietary interventions. Since bacterial species have different metabolic activities, specific diets have various consequences for health, dependent on the effect exerted on the bacterial population.
journal_name
Biochem Soc Transjournal_title
Biochemical Society transactionsauthors
Scott KP,Duncan SH,Louis P,Flint HJdoi
10.1042/BST0391073subject
Has Abstractpub_date
2011-08-01 00:00:00pages
1073-8issue
4eissn
0300-5127issn
1470-8752pii
BST0391073journal_volume
39pub_type
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