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Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications.

Abstract：

:Micro Electromechanical Systems (MEMS) based microfluidic devices have gained popularity in biomedicine field over the last few years. In this paper, a comprehensive overview of microfluidic devices such as micropumps and microneedles has been presented for biomedical applications. The aim of this paper is to present the major features and issues related to micropumps and microneedles, e.g., working principles, actuation methods, fabrication techniques, construction, performance parameters, failure analysis, testing, safety issues, applications, commercialization issues and future prospects. Based on the actuation mechanisms, the micropumps are classified into two main types, i.e., mechanical and non-mechanical micropumps. Microneedles can be categorized according to their structure, fabrication process, material, overall shape, tip shape, size, array density and application. The presented literature review on micropumps and microneedles will provide comprehensive information for researchers working on design and development of microfluidic devices for biomedical applications.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Ashraf MW,Tayyaba S,Afzulpurkar N

doi

10.3390/ijms12063648

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

3648-704

issue

6

issn

1422-0067

pii

ijms-12-03648

journal_volume

12

pub_type

杂志文章,评审

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