Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis.

abstract：BACKGROUND:There is growing recognition that horizontal DNA transfer, a process known to be common in prokaryotes, is also a significant source of genomic variation in eukaryotes. Horizontal transfer of transposable elements (HTT) may be especially prevalent in eukaryotes given the inherent mobility, widespread occurre...

journal_title：BMC genomics

authors： Gilbert C,Waters P,Feschotte C,Schaack S

更新日期：2013-02-27 00:00:00

abstract：BACKGROUND:ATP binding cassette (ABC) systems are responsible for the import and export of a wide variety of molecules across cell membranes and comprise one of largest protein superfamilies found in prokarya, eukarya and archea. ABC systems play important roles in bacterial lifestyle, virulence and survival. In this s...

journal_title：BMC genomics

authors： Harland DN,Dassa E,Titball RW,Brown KA,Atkins HS

更新日期：2007-03-28 00:00:00

abstract：BACKGROUND:Fish under intensive culture conditions are exposed to a variety of acute and chronic stressors, including high rearing densities, sub-optimal water quality, and severe thermal fluctuations. Such stressors are inherent in aquaculture production and can induce physiological responses with adverse effects on t...

journal_title：BMC genomics

authors： Sánchez CC,Weber GM,Gao G,Cleveland BM,Yao J,Rexroad CE 3rd

更新日期：2011-12-21 00:00:00

abstract：BACKGROUND:The mitochondrial genomes of higher plants vary remarkably in size, structure and sequence content, as demonstrated by the accumulation and activity of repetitive DNA sequences. Incompatibility between mitochondrial genome and nuclear genome leads to non-functional male reproductive organs and results in cyt...

journal_title：BMC genomics

authors： Li S,Chen Z,Zhao N,Wang Y,Nie H,Hua J

更新日期：2018-10-26 00:00:00

abstract：BACKGROUND:Many computational methods are available for assembly and annotation of newly sequenced microbial genomes. However, when new genomes are reported in the literature, there is frequently very little critical analysis of choices made during the sequence assembly and gene annotation stages. These choices have a ...

journal_title：BMC genomics

authors： Morrison SS,Pyzh R,Jeon MS,Amaro C,Roig FJ,Baker-Austin C,Oliver JD,Gibas CJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Dermal papilla cells (DPCs), the "signaling center" of hair follicle (HF), delicately master continual growth of hair in mammals including cashmere, the fine fiber annually produced by secondary HF embedded in cashmere goat skins. Such unparalleled capacity bases on their exquisite character in instructing t...

journal_title：BMC genomics

authors： Ma S,Wang Y,Zhou G,Ding Y,Yang Y,Wang X,Zhang E,Chen Y

更新日期：2019-06-20 00:00:00

abstract：BACKGROUND:Complete or near-complete genomic sequence information is presently only available for a few plant species representing a large phylogenetic diversity among plants. In order to effectively transfer this information to species lacking sequence information, comparative genomic tools need to be developed. Molec...

journal_title：BMC genomics

authors： Fredslund J,Madsen LH,Hougaard BK,Nielsen AM,Bertioli D,Sandal N,Stougaard J,Schauser L

更新日期：2006-08-14 00:00:00

abstract：BACKGROUND:Subtilisin/kexin-like proprotein convertase (PCSK) enzymes have important regulatory function in a wide variety of biological processes. PCSKs proteolytically process at a target sequence that contains basic amino acids arginine and lysine, which results in functional maturation of the target protein. In vit...

journal_title：BMC genomics

authors： Turpeinen H,Kukkurainen S,Pulkkinen K,Kauppila T,Ojala K,Hytönen VP,Pesu M

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Grass carp (Ctenopharyngodon idella) belongs to the family Cyprinidae which includes more than 2000 fish species. It is one of the most important freshwater food fish species in world aquaculture. A linkage map is an essential framework for mapping traits of interest and is often the first step towards under...

journal_title：BMC genomics

authors： Xia JH,Liu F,Zhu ZY,Fu J,Feng J,Li J,Yue GH

更新日期：2010-02-24 00:00:00

abstract：BACKGROUND:Phanerochaete chrysosporium, the model white rot basidiomycetous fungus, has the extraordinary ability to mineralize (to CO2) lignin and detoxify a variety of chemical pollutants. Its cytochrome P450 monooxygenases have recently been implied in several of these biotransformations. Our initial P450 cloning ef...

journal_title：BMC genomics

authors： Doddapaneni H,Chakraborty R,Yadav JS

更新日期：2005-06-14 00:00:00

abstract：BACKGROUND:Environmental heterogeneity continuously produces a selective pressure that results in genomic variation among organisms; understanding this relationship remains a challenge in evolutionary biology. Here, we evaluated the degree of genome-environmental association of seven stonefly species across a wide geog...

journal_title：BMC genomics

authors： Gamboa M,Watanabe K

更新日期：2019-01-24 00:00:00

abstract：BACKGROUND:Clostridium botulinum is a diverse group of bacteria characterized by the production of botulinum neurotoxin. Botulinum neurotoxins are classified into serotypes (BoNT/A-G), which are produced by six species/Groups of Clostridia, but the genetic background of the bacteria remains poorly understood. The purpo...

journal_title：BMC genomics

authors： Williamson CH,Sahl JW,Smith TJ,Xie G,Foley BT,Smith LA,Fernández RA,Lindström M,Korkeala H,Keim P,Foster J,Hill K

更新日期：2016-03-03 00:00:00

abstract：BACKGROUND:Polypyrimidine-tract binding proteins (PTBs) are ubiquitous RNA-binding proteins in plants and animals that play diverse role in RNA metabolic processes. PTB proteins bind to target RNAs through motifs rich in cytosine/uracil residues to fine-tune transcript metabolism. Among tuber and root crops, potato has...

journal_title：BMC genomics

authors： Kondhare KR,Kumar A,Hannapel DJ,Banerjee AK

更新日期：2018-02-07 00:00:00

abstract：BACKGROUND:Many species of the genus Prevotella are pathogens that cause oral diseases. Prevotella intermedia is known to cause various oral disorders e.g. periodontal disease, periapical periodontitis and noma as well as colonize in the respiratory tract and be associated with cystic fibrosis and chronic bronchitis. I...

journal_title：BMC genomics

authors： Ruan Y,Shen L,Zou Y,Qi Z,Yin J,Jiang J,Guo L,He L,Chen Z,Tang Z,Qin S

更新日期：2015-02-25 00:00:00

abstract：BACKGROUND:Small insertions and deletions (InDels) constitute the second most abundant class of genetic variants and have been found to be associated with many traits and diseases. The present study reports on the detection and characterisation of about 883 K high quality InDels from the whole-genome analysis of severa...

journal_title：BMC genomics

authors： Boschiero C,Gheyas AA,Ralph HK,Eory L,Paton B,Kuo R,Fulton J,Preisinger R,Kaiser P,Burt DW

更新日期：2015-07-31 00:00:00

abstract：BACKGROUND:Cornu aspersum is a quite intriguing species from the point of view of ecology and evolution and its potential use in medical and environmental applications. It is a species of economic importance since it is farmed and used for culinary purposes. However, the genomic tools that would allow a thorough insigh...

journal_title：BMC genomics

authors： Parmakelis A,Kotsakiozi P,Kontos CK,Adamopoulos PG,Scorilas A

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:Understanding polyphenism, the ability of a single genome to express multiple morphologically and behaviourally distinct phenotypes, is an important goal for evolutionary and developmental biology. Polyphenism has been key to the evolution of the Hymenoptera, and particularly the social Hymenoptera where the...

journal_title：BMC genomics

authors： Colgan TJ,Carolan JC,Bridgett SJ,Sumner S,Blaxter ML,Brown MJ

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Matricaria recutita (German chamomile) and Chamaemelum nobile (Roman chamomile) belong to the botanical family Asteraceae. These two herbs are not only morphologically distinguishable, but their secondary metabolites - especially the essential oils present in flowers are also different, especially the terpen...

journal_title：BMC genomics

authors： Tai Y,Hou X,Liu C,Sun J,Guo C,Su L,Jiang W,Ling C,Wang C,Wang H,Pan G,Si X,Yuan Y

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:CRISPR is a microbial immune system likely to be involved in host-parasite coevolution. It functions using target sequences encoded by the bacterial genome, which interfere with invading nucleic acids using a homology-dependent system. The system also requires protospacer associated motifs (PAMs), short moti...

journal_title：BMC genomics

authors： Kupczok A,Bollback JP

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:Microsatellites are widely used for many genetic studies. In contrast to single nucleotide polymorphism (SNP) and genotyping-by-sequencing methods, they are readily typed in samples of low DNA quality/concentration (e.g. museum/non-invasive samples), and enable the quick, cheap identification of species, hyb...

journal_title：BMC genomics

authors： Dawson DA,Ball AD,Spurgin LG,Martín-Gálvez D,Stewart IR,Horsburgh GJ,Potter J,Molina-Morales M,Bicknell AW,Preston SA,Ekblom R,Slate J,Burke T

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases. The family prototype PDIA1 is also involved in vascular redox cell signaling. PDIA1 is coded by the P4HB gene. While forced chan...

journal_title：BMC genomics

authors： Kajihara D,Hon CC,Abdullah AN,Wosniak J Jr,Moretti AIS,Poloni JF,Bonatto D,Hashimoto K,Carninci P,Laurindo FRM

更新日期：2020-11-04 00:00:00

abstract：BACKGROUND:Wheat is the most important staple crop in Afghanistan and accounts for the main part of cereal production. However, wheat production has been unstable during the last decades and the country depends on seed imports. Wheat research in Afghanistan has emphasized releases of new, high-yielding and disease resi...

journal_title：BMC genomics

authors： Dreisigacker S,Sharma RK,Huttner E,Karimov A,Obaidi MQ,Singh PK,Sansaloni C,Shrestha R,Sonder K,Braun HJ

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:The pituitary is a critical neuroendocrine gland that is comprised of five hormone-secreting cell types, which develops in tandem during the embryonic stage. Some essential genes have been identified in the early stage of adenohypophysial development, such as PITX1, FGF8, BMP4 and SF-1. However, it is likely...

journal_title：BMC genomics

authors： Ma Y,Qi X,Du J,Song S,Feng D,Qi J,Zhu Z,Zhang X,Xiao H,Han Z,Hao X

更新日期：2009-03-15 00:00:00

abstract：BACKGROUND:Large-scale comparison of metazoan genomes has revealed that a significant fraction of genes of the last common ancestor of Bilateria (Urbilateria) is lost in each animal lineage. This event could be one of the underlying mechanisms involved in generating metazoan diversity. However, the present functions of...

journal_title：BMC genomics

authors： Matsui T,Yamamoto T,Wyder S,Zdobnov EM,Kadowaki T

更新日期：2009-01-12 00:00:00

abstract：BACKGROUND:Mytilisepta virgata is a marine mussel commonly found along the coasts of Japan. Although this species has been the subject of occasional studies concerning its ecological role, growth and reproduction, it has been so far almost completely neglected from a genetic and molecular point of view. In the present ...

journal_title：BMC genomics

authors： Gerdol M,Fujii Y,Hasan I,Koike T,Shimojo S,Spazzali F,Yamamoto K,Ozeki Y,Pallavicini A,Fujita H

更新日期：2017-08-08 00:00:00

abstract：BACKGROUND:Circular chromosome conformation capture (4C) has provided important insights into three dimensional (3D) genome organization and its critical impact on the regulation of gene expression. We developed a new quantitative framework based on polymer physics for the analysis of paired-end sequencing 4C (PE-4Cseq...

journal_title：BMC genomics

authors： Zepeda-Mendoza CJ,Mukhopadhyay S,Wong ES,Harder N,Splinter E,de Wit E,Eckersley-Maslin MA,Ried T,Eils R,Rohr K,Mills A,de Laat W,Flicek P,Sengupta AM,Spector DL

更新日期：2015-11-21 00:00:00

abstract：BACKGROUND:Alternative polyadenylation (APA) has emerged as a pervasive mechanism that contributes to the transcriptome complexity and dynamics of gene regulation. The current tsunami of whole genome poly(A) site data from various conditions generated by 3' end sequencing provides a valuable data source for the study o...

journal_title：BMC genomics

authors： Ye W,Long Y,Ji G,Su Y,Ye P,Fu H,Wu X

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:Nucleosomes facilitate the packaging of the eukaryotic genome and modulate the access of regulators to DNA. A detailed description of the nucleosomal organization under different transcriptional programmes is essential to understand their contribution to genomic regulation. RESULTS:To visualize the dynamics...

journal_title：BMC genomics

authors： Soriano I,Quintales L,Antequera F

更新日期：2013-11-21 00:00:00

abstract：BACKGROUND:The disease caused by Haemonchus contortus, a blood-feeding nematode of small ruminants, is of major economic importance worldwide. The infective third-stage larva (L3) of this gastric nematode is enclosed in a cuticle (sheath) and, once ingested with herbage by the host, undergoes an exsheathment process th...

journal_title：BMC genomics

authors： Cantacessi C,Campbell BE,Young ND,Jex AR,Hall RS,Presidente PJ,Zawadzki JL,Zhong W,Aleman-Meza B,Loukas A,Sternberg PW,Gasser RB

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:The AP2/ERF transcription factor, one of the largest gene families in plants, plays a crucial role in the regulation of growth and development, metabolism, and responses to biotic and abiotic stresses. Castor bean (Ricinus communis L., Euphobiaceae) is one of most important non-edible oilseed crops and its s...

journal_title：BMC genomics

authors： Xu W,Li F,Ling L,Liu A

更新日期：2013-11-13 00:00:00