The influence of early environmental exposures on immune development and subsequent risk of allergic disease.

Abstract:

:Environmental exposures in pregnancy and the early postnatal period affect early immune development. Early immune function and future allergy susceptibility appear to result from a combination of maternal phenotype, infant genotype, and environmental exposures in utero that affect early gene expression. Furthermore, epigenetic changes in gene expression in one generation can also be inherited across subsequent generations, potentially amplifying heritable allergy risk.

journal_name

Allergy

journal_title

Allergy

authors

Prescott SL

doi

10.1111/j.1398-9995.2011.02620.x

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

4-6

eissn

0105-4538

issn

1398-9995

journal_volume

66 Suppl 95

pub_type

杂志文章

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