Chemical constituents from the roots of Feroniella lucida.

Abstract:

:A new furanocoumarin named lucidafuranocoumarin A (7) together with 13 known coumarins (1-6, 8-14) and four known alkaloids (15-18) was isolated from the roots of Feroniella lucida. Their structures were elucidated on the basis of spectroscopic analysis. Some of the isolates were evaluated for their biological activities, and compound 18 showed strong cytotoxicity against KB (IC(50) = 0.637 μg/ml) and NCI-H187 (IC(50) = 0.094 μg/ml) human cancer cell lines, antimalarial activity against Plasmodium falciparum (IC(50) = 0.336 μg/ml), and antituberculosis activity against Mycobacterium tuberculosis (MIC = 6.25 μg/ml).

journal_name

J Asian Nat Prod Res

authors

Sripisut T,Cheenpracha S,Laphookhieo S

doi

10.1080/10286020.2011.572878

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

556-60

issue

6

eissn

1028-6020

issn

1477-2213

pii

938013876

journal_volume

13

pub_type

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