Abstract:
:A new furanocoumarin named lucidafuranocoumarin A (7) together with 13 known coumarins (1-6, 8-14) and four known alkaloids (15-18) was isolated from the roots of Feroniella lucida. Their structures were elucidated on the basis of spectroscopic analysis. Some of the isolates were evaluated for their biological activities, and compound 18 showed strong cytotoxicity against KB (IC(50) = 0.637 μg/ml) and NCI-H187 (IC(50) = 0.094 μg/ml) human cancer cell lines, antimalarial activity against Plasmodium falciparum (IC(50) = 0.336 μg/ml), and antituberculosis activity against Mycobacterium tuberculosis (MIC = 6.25 μg/ml).
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Sripisut T,Cheenpracha S,Laphookhieo Sdoi
10.1080/10286020.2011.572878subject
Has Abstractpub_date
2011-06-01 00:00:00pages
556-60issue
6eissn
1028-6020issn
1477-2213pii
938013876journal_volume
13pub_type
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