Percutaneous nephrostomy - recovered renal-function in 50 obstetric and gynecologic patients undergoing percutaneous nephrostomy.

abstract：:Hsp90α is a molecular chaperone protein involved in the structural maturation of oncogenic signaling proteins. Hsp90 was recently identified as an anticancer target; various studies are ongoing to find ways for managing cancer through Hsp90α. However, this approach is limited by reported side-effects. Hypoxia is a hal...

journal_title：International journal of oncology

authors： Pak SH,Joung YH,Park JH,Lim EJ,Darvin P,Na YM,Hong DY,Lee B,Hwang TS,Park T,Ye SK,Moon ES,Cho BW,Park KD,Lee HK,Chung IM,Yang YM

更新日期：2012-07-01 00:00:00

abstract：:Fucoidan, a sulfated polysaccharide, has significant cytotoxic activity against tumor cells; however, the mechanism(s) of this action remains poorly understood. The present study was designed to determine the in vitro and in vivo effects of fucoidan and their molecular mechanisms. F...

journal_title：International journal of oncology

authors： Takeda K,Tomimori K,Kimura R,Ishikawa C,Nowling TK,Mori N

更新日期：2012-01-01 00:00:00

abstract：:Metallothionein 3 (MT-3) has the ability to regulate the growth of nerve cells, but the significance of MT-3 expression outside the central nervous system and its participation in carcinogenesis have not yet been clarified. The aim of our study was to investigate the expression of MT-3 in ductal breast cancer and to d...

journal_title：International journal of oncology

authors： Gomulkiewicz A,Jablonska K,Pula B,Grzegrzolka J,Borska S,Podhorska-Okolow M,Wojnar A,Rys J,Ambicka A,Ugorski M,Zabel M,Dziegiel P

更新日期：2016-12-01 00:00:00

abstract：:According to the current concept of carcinogenesis, neoplastic transformation consists of multistep accumulations of adverse genetic and epigenetic events. Recent advances in molecular genetics have demonstrated aberrations of oncogenes and tumor-suppressor genes in a variety of human cancers. The loss of wild-type p5...

journal_title：International journal of oncology

authors： Furihata M,Sonobe H,Ohtsuki Y

更新日期：1995-06-01 00:00:00

abstract：:Fatty acid synthase (FASN) is a key enzyme that plays a critical role in numerous metabolic functions by catalyzing the synthesis for long-chain fatty acids. FASN is highly expressed in various human cancers. This preferential expression makes FASN an attractive target for anticance...

journal_title：International journal of oncology

authors： Jeong NY,Yoo YH

更新日期：2012-06-01 00:00:00

abstract：:Eukaryotic initiation factor 3c (eIF3C) is involved in the initiation of protein translation. Aberrant eIF3C expression has been reported in different types of human cancer. The present study aimed to assess the role of eIF3C in the malignant behavior of renal cell carcinoma in vitro and in vivo. eIF3C expression was ...

journal_title：International journal of oncology

authors： Fan M,Wang K,Wei X,Yao H,Chen Z,He X

更新日期：2019-12-01 00:00:00

abstract：:Thirty-one patients with metastatic breast cancer not responding or progressing after initial response to adriamycin + cyclophosphamide (AC) treatment entered a phase 11 study with oral lonidamine in association to AC. Objective clinical responses were observed in 10 patients (32%) and consisted of 1 complete + 9 part...

journal_title：International journal of oncology

authors： Tomirotti M,Bernardo G,Epifani C,Biasioli R,Franchi R,Mensi F,Carnaghi P,Schieppati G,Scanni A

更新日期：1993-08-01 00:00:00

abstract：:Using two malignant rat glioma cell lines, we tested to what extent peripheral immunization could affect tumor growth in the brain of syngeneic rats. Peripheral subcutaneous (s.c.) immunization was performed with autologous Newcastle-disease-virus (NDV)-infected or non-infected live tumor cells. Thus immunized rats or...

journal_title：International journal of oncology

authors： Naujocks G,Schmitz A,Schramm J,Wiestler O,Schirrmacher V

更新日期：1995-04-01 00:00:00

abstract：:In this communication we show that overexpression of the human TATA-binding protein (TBP) activates a synthetic promoter with p53-binding sites in the presence of wild-type p53. No activation is observed in the absence of wild-type p53 in Saos-2 cells. Perhaps, TBP is limiting in these cells for the p53-mediated activ...

journal_title：International journal of oncology

authors： Deb S,Brown D,Lega H,Deb S

更新日期：1995-01-01 00:00:00

abstract：:Hepatitis B X-interacting protein (HBXIP) is a novel oncoprotein. We have previously reported that HBXIP promotes the proliferation and migration of breast cancer cells. S-phase kinase-associated protein 2 (Skp2) is another oncoprotein which is important for migration. In this study, we investigated whether Skp2 is in...

journal_title：International journal of oncology

authors： Xu F,Zhu X,Han T,You X,Liu F,Ye L,Zhang X,Wang X,Yao Y

更新日期：2014-07-01 00:00:00

abstract：:The cytosine analogue 5'-azacytidine (5'-aza) induces DNA hypomethylation by inhibiting DNA methyltransferase. In clinical trials, 5'-aza is widely used in epigenetic anticancer treatments. Accumulated evidence shows that cyclooxygenase-2 (COX-2) is overexpressed in various cancers, indicating that it may play a criti...

journal_title：International journal of oncology

authors： Yu SM,Kim SJ

更新日期：2015-10-01 00:00:00

abstract：:Ovarian cancer is a lethal malignancy, rarely diagnosed early, and there is currently little, if any, preventive strategies which can be followed. This study attempts to identify lifestyle profiles which might be associated with ovarian cancer, and could then be subject to subsequent modification in an effort to preve...

journal_title：International journal of oncology

authors： Loesch M,Fischer M,Shurpin K,Mann W

更新日期：1994-03-01 00:00:00

abstract：:Many clinical studies highlight the dichotomous role of PRDXs in human cancers, where they can exhibit strong tumor-suppressive or tumor-promoting functions. Recent evidence suggests that lower expression of PRDXs correlates with cancer progression in colorectal cancer (CRC) or in esophageal squamous carcinoma. In the...

journal_title：International journal of oncology

authors： Nicolussi A,D'Inzeo S,Mincione G,Buffone A,Di Marcantonio MC,Cotellese R,Cichella A,Capalbo C,Di Gioia C,Nardi F,Giannini G,Coppa A

更新日期：2014-02-01 00:00:00

abstract：:In the present study, we report the utility of transrectal ultrasonography guidance for laparoscopic radical prostatectomy (LRP), and the effect of a novel surgical approach of 'seven key elements of operative skill for the early recovery of urinary continence' ('7 key elements'). Among 170 patients who underwent lapa...

journal_title：International journal of oncology

authors： Azuma H,Ibuki N,Inamoto T,Koyama K,Utimoto S,Fujisue Y,Mizutani Y,Nomi H,Ubai T,Katsuoka Y

更新日期：2011-02-01 00:00:00

abstract：:Malignant gliomas are diffuse infiltrative growing tumors with a poor prognosis despite treatment with a combination of surgery, radiotherapy and chemotherapy. It has been shown recently that complete tumor resection improves the survival time significantly. Hypericin, a component of St. Johns Wort, is one of the most...

journal_title：International journal of oncology

authors： Noell S,Mayer D,Strauss WS,Tatagiba MS,Ritz R

更新日期：2011-05-01 00:00:00

abstract：:The expression of proinflammatory cytokines in various malignant neoplasms is widely considered to represent the host immune response to tumor development. The role of interferon (IFN)γ in head and neck squamous cell carcinoma, and its association with endoplasmic reticulum (ER) stress pathways, remains a subject of o...

journal_title：International journal of oncology

authors： Gkouveris I,Nikitakis NG,Aseervatham J,Ogbureke KUE

更新日期：2018-12-01 00:00:00

abstract：:We established a new lymphoma cell line, designated CTB-1, from pericardial effusion of a patient with diffuse large B-cell lymphoma. This cell line showing vigorous growth ability has undergone 260 passages over a period of 34 months in suspension culture, and is heterotransplantable to nude mice. The cultured cells ...

journal_title：International journal of oncology

authors： Uchida Y,Miyazawa K,Yaguchi M,Gotoh A,Iwase O,Ohyashiki K,Toyama K

更新日期：1997-06-01 00:00:00

abstract：:Tumor cell invasion and metastasis requires precise coordination of adherence to the extracellular matrix (ECM) and controlled degradation of its components. lnvasive cells secrete proteolytic enzymes known as matrix metalloproteinases which degrade specific basement membrane molecules. Expression of these enzymes is ...

journal_title：International journal of oncology

authors： Vo HP,Lee MK,Crowe DL

更新日期：1998-12-01 00:00:00

abstract：:In order to optimize the management of patients with renal cell carcinoma (RCC) it is important to define the genetic risk for metastatic disease. In this study we performed comparative genomic hybridization (CGH) on metastatic tumors aiming at the identification of genetic alterations associated with metastatic disea...

journal_title：International journal of oncology

authors： Junker K,Moravek P,Podhola M,Weirich G,Hindermann W,Janitzky V,Schubert J

更新日期：2000-11-01 00:00:00

abstract：:Combination therapy is a promising and prevalent strategy for osteosarcoma treatment. Curcumin (CUR), as a chemosensitizer, improves the antitumor effect of first‑line chemotherapy drugs. However, due to its poor solubility and instability in physiological conditions, the bioavailability of CUR is limited. In order to...

journal_title：International journal of oncology

authors： Yang Z,Liu J,Lu Y

更新日期：2020-08-01 00:00:00

abstract：:The overall goal of the present study was to evaluate the chemotherapeutic and cancer‑protective properties of D‑erythro‑sphingosine (sphingosine) and C2‑ceramide using a human breast epithelial cell (HBEC) culture system, which represents multiple‑stages of breast carcinogenesis. The HBEC model includes Type I HBECs ...

journal_title：International journal of oncology

authors： Ahn EH,Yang H,Hsieh CY,Sun W,Chang CC,Schroeder JJ

更新日期：2019-02-01 00:00:00

abstract：:This study examined whether the soluble tumor-associated antigens (sTAA) of 66 kDa and 51 kDa could promote suppression of chemically-induced rat mammary tumorigenesis by the hormone-related anticancer drug tamoxifen and prevent the drug's toxic side-effects. Dimethylbenzanthracene (DMBA, 10 mg/rat, 3 administrations)...

journal_title：International journal of oncology

authors： Ben-Hur H,Kossoy G,Zusman I

更新日期：2002-02-01 00:00:00

abstract：:CDC28 protein kinase regulatory subunit 2 (CKS2) is a cyclin-dependent kinase subunit (CKS) family member that participates in cell cycle regulation. Few studies have investigated its involvement in gastric cancer. In this study, we focused on the clinical and biological significance of CKS2 over-expression in gastric...

journal_title：International journal of oncology

authors： Tanaka F,Matsuzaki S,Mimori K,Kita Y,Inoue H,Mori M

更新日期：2011-08-01 00:00:00

abstract：:Radioiodinated meta-iodobenzylguanidine (MIBG), an analogue of norepinephrine, has been used in management of neuroendocrine tumors. Recent studies reveal that distribution of radioiodinated MIBG in animals depends on the specific activity of this radiopharmaceutical. In order to clarify the effect of specific activit...

journal_title：International journal of oncology

authors： Farahati J,Lassmann M,Scheubeck M,Bier D,Hanscheid H,Schelper L,Grelle I,Biko J,Werner E,Graefe K,Reiners C

更新日期：1997-04-01 00:00:00

abstract：:MCA serum levels were determined in 196 patients with benign breast disease (BD) and in 371 patients with breast cancer. MCA values were abnormal in 30.6% of the patients with BD. In breast cancer patients, significant increases were only found in metastatic disease (89.1%). MCA levels were not correlated with tumor s...

journal_title：International journal of oncology

authors： Donadeo A,Lorusso V,Micelli G,Quaranta M,Muncipinto A,Schittulli F

更新日期：1993-02-01 00:00:00

abstract：:Bcl-xL is an apoptosis inhibitor that is upregulated in bladder cancer (BCa) and provides an attractive target for molecular therapies. Treatment with specific antisense oligodeoxynucleotides (AS‑ODNs) or small interfering RNAs (siRNAs) were able to sensitize BCa cells to conventional chemotherapeutics. Ten new Bcl‑xL...

journal_title：International journal of oncology

authors： Rieger C,Huebner D,Temme A,Wirth MP,Fuessel S

更新日期：2015-09-01 00:00:00

abstract：:The expression of mucinous ovarian cancer (OVC) antigen by hybrid cell lines derived by fusing a malignantly transformed Bloom syndrome (BS) cell line (BS-SHI-4M OVC-MU) and mouse L cells has been studied. Cell surfaces of 16 hybrids which grew 12-40 days post-fusion have been analysed by using a number of sera from m...

journal_title：International journal of oncology

authors： Shiraishi Y,Taguchi T,Seguchi H

更新日期：1995-12-01 00:00:00

abstract：:Thirty-three adult patients with anaplastic astrocytoma or glioblastoma multiforme, verified between 1990 and 1997, received postoperative intra-arterial ACNU chemotherapy and irradiation. Since our previous strategies to malignant gliomas had included intra-venous ACNU, the purpose of the present study is to evaluate...

journal_title：International journal of oncology

authors： Hirano Y,Mineura K,Mizoi K,Tomura N

更新日期：1998-09-01 00:00:00

abstract：:We demonstrated previously that rat ascites hepatoma MM1 cells require both lysophosphatidic acid (LPA) and fibronectin (FN) for phagokinetic motility and transcellular migration and that these events are regulated through the RhoA-ROCK pathway and tyrosine phosphorylation of proteins including focal adhesion kinase (...

journal_title：International journal of oncology

authors： Mukai M,Iwasaki T,Tatsuta M,Togawa A,Nakamura H,Murakami-Murofushi K,Kobayashi S,Imamura F,Inoue M

更新日期：2003-06-01 00:00:00

abstract：:Malignant peripheral nerve sheath tumor (MPNST) is a rare malignant tumor, for which only a few cultured cell lines are available to date. In the present study, we established three new MPNST cell lines, FU-SFT8611, FU-SFT8710 and FU-SFT9817, from a 40-year-old Japanese man without neurofibromatosis 1 (NF1), a 43-year...

journal_title：International journal of oncology

authors： Aoki M,Nabeshima K,Nishio J,Ishiguro M,Fujita C,Koga K,Hamasaki M,Kaneko Y,Iwasaki H

更新日期：2006-12-01 00:00:00