Abstract：
:The knowledge on immune mechanisms of chronic urticaria (CU) at the cytokine level is widely scarce. We compared pro- and anti-inflammatory as well as Th1- and Th2-associated serum cytokine levels in two phenotypes of CU: associated with (CU+) and without (CU⁻) sensitization against Anisakis simplex, a ubiquitous fish parasite, that has been associated with acute urticaria in gastro-allergic anisakiasis (GAA) and with CU+. Thirteen CU+ and 19 CU⁻ patients were compared with 13 GAA patients and 15 control subjects for cytokines, measured by cytometric bead array. Urticaria activity score was positively correlated with IL-6 in CU⁻. Serum levels of IL-10 were lower in CU+ and CU⁻ with respect to the control group. Median IFN-γ was lower in all urticaria groups. Patients with previous parasitism by A. simplex displayed higher TGF-β levels than subjects without previous parasitism. The main finding was lower levels of IL-17 in CU+ with respect to GAA or controls, with a further tendency to even lower levels in CU⁻. Different urticaria phenotypes are associated with distinct serum cytokine levels.
journal_name
Parasite Immunoljournal_title
Parasite immunologyauthors
Daschner A,Rodero M,DE Frutos C,Valls A,Vega F,Blanco C,Cuéllar Cdoi
10.1111/j.1365-3024.2011.01282.xsubject
Has Abstractpub_date
2011-06-01 00:00:00pages
357-62issue
6eissn
0141-9838issn
1365-3024journal_volume
33pub_type
杂志文章abstract：:Chronic Chagas cardiomyopathy (CCC) is responsible for the disease's greater morbidity and poor prognosis. Although understanding the pathophysiology of CCC and the fundamentals of its clinical management derives from research related to other cardiomyopathies, there are peculiarities that distinguish CCC from the oth...
journal_title：Parasite immunology
pub_type： 杂志文章,评审
doi：10.1111/pim.12663
更新日期：2019-10-01 00:00:00
abstract：:Human recombinant tumour necrosis factor (rTNF) enhanced monoclonal IgE-dependent eosinophil-mediated cytotoxicity to schistosomula of Schistosoma japonicum in a dose-dependent manner. The enhancing effect of rTNF was also observed for the antibody-dependent cytotoxicity of a human eosinophilic leukemia cell line, EoL...
journal_title：Parasite immunology
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doi：10.1111/j.1365-3024.1992.tb00033.x
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journal_title：Parasite immunology
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doi：10.1111/j.1365-3024.1989.tb00669.x
更新日期：1989-07-01 00:00:00
abstract：AIMS:Industrial growth has increased the exposure to endocrine disruptor compounds (EDCs) in all organisms. Bisphenol A (BPA), an EDC, has been demonstrated to be involved in the susceptibility to parasite infections. However, few studies have analysed this connection in more depth. The aim of this study was to determi...
journal_title：Parasite immunology
pub_type： 杂志文章
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更新日期：2020-09-01 00:00:00
abstract：:Serum antibody responses of mice exposed to Philippine isolates of Schistosoma japonicum have been analysed by immunoprecipitation of exogenously radiolabelled antigens extracted from adult worms. Attention was focused on labelled protein antigens differentially recognized by sera of mice that differ genetically in th...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1985.tb00067.x
更新日期：1985-03-01 00:00:00
abstract：:Cutaneous leishmaniasis, caused by the parasite Leishmania major, results in lesions at the site of infection, which are self-healing in resistant hosts. However, in the absence of the chemokine receptor CCR7, mice are unable to heal the lesion and develop chronic disease. These B6.CCR7(-/-) mice display an increased ...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/pim.12097
更新日期：2014-04-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1994.tb00320.x
更新日期：1994-12-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
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更新日期：1987-05-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1993.tb00577.x
更新日期：1993-11-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.1365-3024.1998.00160.x
更新日期：1998-08-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1979.tb00701.x
更新日期：1979-07-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/pim.12658
更新日期：2019-08-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/pim.12071
更新日期：2014-01-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.1365-3024.2002.00448.x
更新日期：2002-03-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1993.tb00574.x
更新日期：1993-11-01 00:00:00
abstract：:Particular immunopathological features and their effects on the vascular permeability of different ocular structures were analysed in two dogs naturally infected by Leishmania infantum. The existence of specific anti-Leishmania immunoglobulin G (IgG) in the aqueous humour was confirmed by the ELISA technique. There wa...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.1365-3024.1996.d01-39.x
更新日期：1996-12-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/pim.12535
更新日期：2018-07-01 00:00:00
abstract：:Fasciola hepatica infection has been shown to suppress sheep lymphocyte proliferation in vitro and this is at least partially attributable to excretory/secretory products (ES) released by F. hepatica parasites. We identified a suppressive component in ES by analysing the effect of ES fractions, separated by gel filtra...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.0141-9838.2001.00438.x
更新日期：2002-02-01 00:00:00
abstract：:Host cell death induced by Entamoeba histolytica is an important mechanism for both host defence and microbial immune evasion during human amoebiasis. However, the signalling pathways underlying cell death induced by E. histolytica are not fully understood. This study investigated the involvement of the protein tyrosi...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.2009.01175.x
更新日期：2010-03-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1994.tb00299.x
更新日期：1994-01-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.2011.01337.x
更新日期：2011-12-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1983.tb00736.x
更新日期：1983-03-01 00:00:00
abstract：:A 17 kD protein of Necator americanus was isolated by SDS-PAGE and used to raise monospecific antisera in rabbits. ELISA and Western blotting against a range of parasite extracts demonstrated the species specificity of this protein. It is expressed at all stages of the life-cycle, appears to be accumulated through the...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1111/j.1365-3024.1990.tb00953.x
更新日期：1990-05-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.1365-3024.2001.00419.x
更新日期：2001-11-01 00:00:00
abstract：:Entamoeba histolytica is the aetiological agent of invasive amoebiasis, the third leading parasitic cause of mortality in the world. The disease can be easily cured by chemotherapy; however, prevention, mainly in the form of vaccination, could greatly decrease the incidence of the disease, and possibly help in its era...
journal_title：Parasite immunology
pub_type： 杂志文章,评审
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更新日期：2003-02-01 00:00:00
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journal_title：Parasite immunology
pub_type： 杂志文章,随机对照试验
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更新日期：2017-06-01 00:00:00
abstract：:Antigenic proteins of Echinostoma caproni (Trematoda) against mouse IgM, IgA, IgG, IgG1 and IgG2a were investigated by immunoproteomics. Excretory/secretory products (ESP) of E. caproni separated by two-dimensional (2D) gel electrophoresis were transferred to nitrocellulose membranes and probed with the different mous...
journal_title：Parasite immunology
pub_type： 杂志文章
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更新日期：2008-05-01 00:00:00
abstract：:Cysteine proteinase enriched fractions obtained by thiol-sepharose chromatography of Ostertagia ostertagi membrane-bound protein extract (S3-thiol) or total adult excretory-secretory (ES-thiol) products were tested in a vaccination experiment to evaluate their protective efficacy against O. ostertagi in cattle. Calves...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.1365-3024.2002.00461.x
更新日期：2002-05-01 00:00:00
abstract：:Antibody isotype and epitope specificities were examined in sheep immunized with EG95, a protective recombinant vaccine against hydatid disease. All sheep immunized with EG95 as a fusion protein with glutathione S-transferase (GST) produced prominent IgG antibodies against the EG95 portion of the protein. Linear, anti...
journal_title：Parasite immunology
pub_type： 杂志文章
doi：10.1046/j.1365-3024.1998.00176.x
更新日期：1998-11-01 00:00:00
abstract：:Toxoplasma gondii is a highly successful parasite that can manipulate host immune responses to optimize its persistence and spread. As a result, a highly complex relationship exists between T. gondii and the immune system of the host. Advances in imaging techniques, and in particular, the application of two-photon mic...
journal_title：Parasite immunology
pub_type： 杂志文章,评审
doi：10.1111/pim.12161
更新日期：2015-03-01 00:00:00
