Suicide by gabapentin overdose.

Abstract:

:Gabapentin is an antiepileptic drug that is prescribed for both FDA-approved and multiple off-label conditions, and has a relatively safe side-effect profile. Rare cases of overdose-related adverse effects have been reported in the literature. Described herein are the circumstances and autopsy findings of a 62-year-old woman with a history of depression, whose death was caused by intentional ingestion of excess gabapentin. The postmortem peripheral blood gabapentin concentration as determined by high-performance liquid chromatography/tandem mass spectroscopy was 88 μg/mL. Previously reported cases of individuals surviving gabapentin overdoses are discussed and compared with this case. Based on a review of the available literature, this appears to be the first published report of a death due solely to gabapentin toxicity.

journal_name

J Forensic Sci

authors

Middleton O

doi

10.1111/j.1556-4029.2011.01798.x

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

1373-5

issue

5

eissn

0022-1198

issn

1556-4029

journal_volume

56

pub_type

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