Engineering plant resistance by constructing chimeric receptors that recognize damage-associated molecular patterns (DAMPs).

Abstract:

:An efficient sensing of danger and a rapid activation of the immune system are crucial for the survival of plants. Conserved pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) and endogenous molecular patterns, which are present only when the tissue is infected or damaged (damage-associated molecular patterns or DAMPs), can act as danger signals and activate the plant immune response. These molecules are recognized by surface receptors that are indicated as pattern recognition receptors (PRRs). In this paper we summarize recent information on oligogalacturonides (OGs), a class of DAMPs that is released from the extracellular matrix of the plant cell during pathogen attack or wounding. We also describe the characteristics of the Arabidopsis Wall-Associated Kinase 1 (WAK1), a PRR recently identified as a receptor of OGs and discuss the use of WAK1, PRRs and chimeric receptors to engineer resistance in crop plants.

journal_name

FEBS Lett

journal_title

FEBS letters

authors

De Lorenzo G,Brutus A,Savatin DV,Sicilia F,Cervone F

doi

10.1016/j.febslet.2011.04.043

subject

Has Abstract

pub_date

2011-06-06 00:00:00

pages

1521-8

issue

11

eissn

0014-5793

issn

1873-3468

pii

S0014-5793(11)00302-4

journal_volume

585

pub_type

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