Abstract:
BACKGROUND:The Fas/Fas ligand (FasL) system has been recognized as an important pathway for apoptosis induction in cells and tissues. It has recently been shown that skin lesions of pemphigus vulgaris are associated with Fas mediated apoptosis. The aim of this study was to evaluate the level of serum soluble Fas of ten newly diagnosed patients with pemphigus vulgaris. METHODS:Sera were collected from ten patients with pemphigus vulgaris. Commercial sandwich enzyme-linked immunosorbent assay (ELISA) for quantitative detection of soluble Fas was applied. RESULTS:Patients with mucosal skin involvement had higher median values in contrast to patients with cutaneous involvement. CONCLUSION:Elevation of soluble Fas in our study may give insights for the pathogenesis of pemphigus vulgaris. Suppression of this underlying mechanism may be an important target for novel therapies and relapse prevention.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Moravvej H,Yousefi M,Farrokhi B,Mosaffa Ndoi
011143/AIM.0011subject
Has Abstractpub_date
2011-05-01 00:00:00pages
200-1issue
3eissn
1029-2977issn
1735-3947pii
0011journal_volume
14pub_type
杂志文章abstract:BACKGROUND:Patients with chronic kidney disease (CKD) have specific dietary needs due to recommended dietary restrictions. However, there is no specific index for evaluating the quality of diet in patients with CKD. OBJECTIVE: To define and compare three specific diet quality indices in patients with CKD. METHODS:Tw...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-08-01 00:00:00
abstract::The purpose of this article is to present the CT features in five cases of pathologically verified Inferior vena cava (IVC) leiomyosarcoma. In this retrospective analysis, we reviewed CT features in 5 cases of clinicopathologically confirmed IVC leiomyosarcoma with respect to its location (infra renal, trans renal, su...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0141705/AIM.0014
更新日期:2014-05-01 00:00:00
abstract::Hepatitis B virus is a hepatotropic virus that causes acute and chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma; it is responsible for more than one million deaths annually worldwide despite hepatitis B vaccination. Until now, there are eight known genotypes (A-H).Clinical course of chronic hepatitis ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:08114/AIM.0019
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Regulation of reproduction is now considered to be carried out by the kisspeptin and its receptor, GPR54 or Kiss1r. Mutations of either Kiss1 or Kiss1r in humans and mice result in profound hypogonadotropic hypogonadism. The present study was aimed to determine whether the levels of kisspeptin are associated...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151801/AIM.005
更新日期:2015-01-01 00:00:00
abstract::Heck's disease or focal epithelial hyperplasia is a benign contagious disease caused by human papillomavirus types 13 or 32. It occurs with low frequency in the Iranian population. This condition is characterized by the occurrence of multiple, small papules or nodules in the oral cavity, especially on the labial and b...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:It is well known that inhalation of chemical warfare, mostly sulfur mustard, causes injury of the respiratory system. Chronic obstructive pulmonary disease is a common disease among these patients. Health-related quality of life is a common feature of studies in chronic obstructive pulmonary disease. The obj...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Genetic and expression anomaly of HER-2 have been frequently observed in different cancers. However, an overall association of HER-2 polymorphism (Ile655Val) with available cancer studies has not yet been explored. In the present study, a probable correlation of HER-2 Ile655Val polymorphism with 6 major type...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,meta分析,评审
doi:0161906/AIM.0011
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:This study ascertained the effects of soy, in the forms of textured soy protein (TSP) and soy nuts, on lipid profiles, apolipoproteins, inflammatory and prothrombotic markers, and blood pressure in elderly women diagnosed with metabolic syndrome (MetS). METHODS:This was a 12-week parallel, randomized, contr...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,随机对照试验
doi:012158/AIM.004
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Estimating burden of disease, injuries and risk factors is crucial for health policy decision making. The Burden of Diseases (BoD) studies provide data about the magnitude and distribution of health problems among the population at national and sub-national levels. The BoD studies are designed to use seconda...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0141701/AIM.005
更新日期:2014-01-01 00:00:00
abstract::Many families are directly involved in caring of their children with the lifelong autistic spectrum disorders. Sometimes, they are the victims of their children's behaviors. The family, including siblings, may have to explain the children's behaviors to others. Their mothers have poorer mental health with difficulties...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:The childhood obesity epidemic is one of the most serious global health challenges, and many relevant policies have been designed and implemented. Regarding health equity policy-making, it is important to adopt proper interventional strategies, including childhood obesity policies. The purpose of this study ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-11-01 00:00:00
abstract::Systemic therapy is one of the cornerstones of cancer treatment. In 1972, following representations by American Society of Clinical Oncology (ASCO), the American Board of Internal Medicine (ABIM) recognized medical oncology as a new subspecialty of internal medicine. Subspecialty of Hematology and Medical Oncology was...
journal_title:Archives of Iranian medicine
pub_type: 历史文章,杂志文章
doi:0151811/AIM.0013
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Paraquat is a bipyridil herbicide and in appropriate and careful usage, will not be health threatening. Most adult cases of intoxication are due to suicidal attempts rather than accidental exposure. Therapeutic response has been reported to be appropriate with high doses of cyclophosphamide and glucocorticoi...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,随机对照试验
doi:08114/AIM.009
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Congenital anomalies play a significant role in perinatal and infantile morbidity and mortality. There is a variation in the frequency of congenital anomalies in different populations. Determination of the prevalence of different types of congenital anomalies may help plan primary prevention measures for the...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:08112/AIM.005
更新日期:2008-03-01 00:00:00
abstract::Head injury is a common occurrence in motor vehicle accidents. There are numerous causes for cranial nerve injury that include head trauma or other lesions. Few studies regarding cranial nerve injury following mild head trauma (GCS: 14 - 15) exist in the literature. The oculomotor nerve is a somatic and visceral motor...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:012159/AIM.0015
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Human rotavirus genotypes G1-G4, G9, P[4] and P[8] are major worldwide causes of acute gastroenteritis in children. Rotavirus genotype G1P[8] is predominant in many countries. In this study, the genotypic diversity of group A rotaviruses were detected in children <5 years of age who were treated for dehydrat...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:011141/AIM.009
更新日期:2011-01-01 00:00:00
abstract::Primary glomus tumors are extremely rare in the liver. To this date, only two cases of primary glomus tumors of the liver have been reported in the literature. This report is the third case of this specified tumor. The patient was a 50 year-old Iranian woman who presented with a history of epigastric pain and nausea. ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0011144/AIM.0015
更新日期:2011-07-01 00:00:00
abstract::Diabetes mellitus is a global health problem affecting 366 million people worldwide and its prevalence is growing rapidly. Diabetic eye disease is present in up to 25% of diabetic subjects. Diabetic retinopathy is a chronic complication of diabetes that can result in blindness. Generally, there are two stages of diabe...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:0121510/AIM.0011
更新日期:2012-10-01 00:00:00
abstract:INTRODUCTION:This research aims to determine the mental health status of population aged 15 and over in the province of Kermanshah in 2015. METHODS:The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Kermanshah in Iran. An estimated sample size of 1200 peo...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:EBOV outbreaks continue to threaten the world due to the absence of effective vaccines and therapeutics. Easy-to-use and rapid diagnostic tests for EBOV are highly desired for prevention and control of the EVD epidemic. METHODS:Escherichia coli expression system was used to express VP40 protein of Zaire Ebo...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0172004/AIM.0011
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome is not uncommon in women of reproductive age. We conducted this study to determine the clinical, hormonal, and biochemical effects of metformin therapy on girls with polycystic ovary syndrome. METHODS:In a self-controlled clinical trial conducted at the Gynecology Center of Yahyane...
journal_title:Archives of Iranian medicine
pub_type: 临床试验,杂志文章
doi:07102/AIM.0010
更新日期:2007-04-01 00:00:00
abstract::This paper presents a systematic literature review of studies that shed light on the health of migrants in Iran from the perspective of social justice. A systematic search was conducted in PubMed and Iranian databases, including IranMedex, Magiran, and SID, in June 2012. All studies that were published until June 2012...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:0161910/AIM.0012
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:Successful isolation of mesenchymal stem cells from waste tissues might be extremely promising for developing stem cell-based therapies. This study aimed to explore whether cells retrieved from teeth extracted due to advanced periodontal disease present mesenchymal stem cell-like properties. METHODS:Pulp ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:015184/AIM.004
更新日期:2015-04-01 00:00:00
abstract::Hydatidosis is an important zoonotic parasite disease in several herbivorous mammals. Human cystic echinococcosis (CE) caused by infection with larval stage of Echinococcus granulosus has been frequently reported from different organs. Here, we report the first case of a urinary echinococcosis in Iran with a pain in t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-08-01 00:00:00
abstract::Placental mesenchymal dysplasia is a rare condition of the placenta and its true incidence and underlying cause has remained unknown till now due to its rarity. Its accurate diagnosis is essential, because placental mesenchymal dysplasia is usually compatible with a good fetal and maternal outcome. A precise ultrasono...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013169/AIM.0013
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Our aim was to determine the association between age at menarche (AAM) and breast cancer adjusted for recall bias (misclassification) in AAM. METHODS:We have used data provided from a case-control study conducted in Iran from 2005 to 2009. The cases and controls were frequency matched based on 5-year age gr...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:There is controversial data available regarding the impact of age at menarche on cardio-metabolic parameters. This community-based study aimed to assess this association among Iranian women. METHODS:We recruited 5,344 eligible women out of 7718, aged 10-50 years who participated in the Tehran lipid and gluc...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Ankylosing spondylitis (AS; OMIM:106300) is a common complex inflammatory disease; in a previous study, we introduced a novel mutation in the RELN gene (OMIM: 600514) which was associated with AS. This study is designed to investigate the potential effect of RELN S2486G mutation on reelin secretion; addition...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:10.34172/aim.2020.87
更新日期:2020-10-01 00:00:00
abstract::Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease caused by germline mutation in Adenomatous Polyposis Coli (APC) gene. FAP accounts less than 1% of all colorectal cancers incidence. Patients generally present hundreds to thousands of adenomas in colon and rectum and develop colorectal ca...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151807/AIM.0010
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The present study reported a six-year follow up of patients with chronic myeloid leukemia who were on imatinib therapy. METHODS:We performed a retrospective study on a total of 417 patients diagnosed with chronic-phase, Philadelphia-positive (Ph+) chronic myeloid leukemia within six months before study entr...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:011146/AIM.004
更新日期:2011-11-01 00:00:00