Immunization with dendritic cells transfected in vivo with HIV-1 plasmid DNA induces HIV-1-specific immune responses.

Abstract:

:We evaluated the importance of dendritic cells (DCs) in the induction of the immune response after immunization of mice with DNA plasmid Auxo-GTU(®)-MultiHIV. First, GTU(®)-encoded protein was shown to be expressed by DCs of the draining lymph nodes (LNs) following intradermal (i.d.) immunization. Next, donor mice were immunized with the MultiHIV DNA plasmid, and DCs were enriched and further used to immunize naïve recipient mice. For the first time, the results show that i.d. immunization with Auxo-GTU(®)-MultiHIV transfects DCs in vivo, enabling them to present antigens and induce HIV-specific immune responses in recipient mice.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Malm M,Krohn K,Blazevic V

doi

10.1007/s00705-011-1003-2

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

1607-10

issue

9

eissn

0304-8608

issn

1432-8798

journal_volume

156

pub_type

杂志文章
  • Lack of correlation between impaired interferon production and natural killer activity of lymphocytes in multiple sclerosis.

    abstract::The ability of lymphocytes from patients with multiple sclerosis (MS) to produce Interferon (IFN-alpha) in response to Newcastle Disease Virus (NDV) was studied in vitro. The correlation between individual IFN-alpha titers and natural killer (NK) cell activity and the presence of HLA system antigens associated with MS...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01314877

    authors: Stöger I,Tálas M,Benczúr M,Gyódi E,Petrányi GG,Pálffy G,Kotsy B

    更新日期:1982-01-01 00:00:00

  • Complete nucleotide sequences of M and L RNAs from a new pepper-infecting tospovirus, Pepper chlorotic spot virus.

    abstract::Pepper chlorotic spot virus (PCSV), newly found in Taiwan, was identified as a new tospovirus based on the molecular characterization of its S RNA. In this study, the complete M and L RNA sequences of PCSV were determined. The M RNA has 4795 nucleotides (nts), encoding the NSm protein of 311 aa (34.5 kDa) in the viral...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-017-3260-1

    authors: Huang KS,Tai CH,Cheng YH,Lin SH,Chen TC,Jan FJ

    更新日期:2017-07-01 00:00:00

  • Experimental immunosuppression induced by herpes simplex virus.

    abstract::Cell-mediated immune response was studied in experimental herpetic infection in mice. Our data suggest that herpes simplex virus induced immunosuppression in mice. This depression was documented by the unresponsiveness of the lymphocytes to PHA stimulation in vitro and by the enhanced susceptibility of adult mice to C...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF02175597

    authors: Cappel R,Henry C,Thiry L

    更新日期:1975-01-01 00:00:00

  • Morphogenesis and structure of caprine respiratory syncytial virus.

    abstract::Cell cultures inoculated with caprine respiratory syncytial virus (RSV) were studied with light, fluorescent, and electron microscopy to determine the morphogenesis and structure of the virus. Small syncytia were seen after 36 hours in culture. After 48 hours in culture, syncytia were large and numerous and pleomorphi...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01314543

    authors: Lehmkuhl HD,Smith MH,Cutlip RC

    更新日期:1980-01-01 00:00:00

  • Genome sequence, prevalence and quantification of the first iflavirus identified in a phytoplasma insect vector.

    abstract::The leafhopper Euscelidius variegatus is a natural vector of chrysanthemum yellows phytoplasma (CY) and an efficient vector of flavescence dorée phytoplasma (FD) under laboratory conditions. During a transcriptome sequencing (RNA-seq) project aimed at investigating the interactions between the insect and the two phyto...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-016-3158-3

    authors: Abbà S,Galetto L,Vallino M,Rossi M,Turina M,Sicard A,Marzachì C

    更新日期:2017-03-01 00:00:00

  • The intestine is a site of passage for potato leafroll virus from the gut lumen into the haemocoel in the aphid vector, Myzus persicae Sulz.

    abstract::Four detection techniques, three of which gave reliable identification of the virus particles, were used to locate potato leafroll virus (PLRV) in the alimentary canal of its main aphid vector, Myzus persicae Sulz: immunofluorescence on cryostat sections, conventional transmission electron microscopy on ultrathin sect...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01378639

    authors: Garret A,Kerlan C,Thomas D

    更新日期:1993-01-01 00:00:00

  • Effect of deletion and the site of insertion in double copy anti-tat retroviral vectors: viral titres and production of anti-tat mRNA.

    abstract::In attempts to further develop murine leukemia virus (MLV) based retroviral vectors for gene therapy, we investigated vector production and antisense expression from retroviral constructs with U3 deletions or insertions. Promoter elements in the U3 region of the 3' LTR of the vector pLXSN were deleted and replaced wit...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050170029

    authors: Carr JM,Calvert JK,Kumar R,Burrel CJ,Li P

    更新日期:2001-01-01 00:00:00

  • Molecular cloning of the genomes of poliovirus type 3 strains by the cDNA: RNA hybrid method.

    abstract::The genomes of two neurovirulent strains of poliovirus type 3, wild type P3/Leon/37 and a vaccine revertant P3/119/70, have been cloned in E. coli. The cDNA: RNA hybrid method used was efficient and may have wide applicability for cDNA cloning. Overlapping clones spanning the entire genome were obtained for each strai...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01309297

    authors: Stanway G,Mountford RC,Cox SD,Schild GC,Minor PD,Almond JW

    更新日期:1984-01-01 00:00:00

  • The role of the C-terminal region of olive latent virus 1 coat protein in host systemic infection.

    abstract::A full-length cDNA clone of olive latent virus 1 (OLV-1), a member of the genus Necrovirus, family Tombusviridae, was subjected to site-directed mutagenesis, and coat protein gene mutants were constructed. A mutant clone, denoted Delta3297, was obtained by deleting the nucleotide in position 3297, thus inducing a fram...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-006-0767-2

    authors: Pantaleo V,Grieco F,Di Franco A,Martelli GP

    更新日期:2006-10-01 00:00:00

  • Anti-idiotypic antibodies against Puumala virus glycoprotein-specific monoclonal antibodies inhibit virus infection in cell cultures.

    abstract::Rabbit anti-idiotypic antibodies (anti-ids) were generated against three bank vole and one human monoclonal antibody (MAb) specific for the two envelope glycoproteins of Puumala virus (G1 and G2). The anti-ids were purified by sequential immunoaffinity chromatography. Each anti-id inhibited the antigen binding of its ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01309537

    authors: Lundkvist A,Scholander C,Niklasson B

    更新日期:1993-01-01 00:00:00

  • Genetic diversity and evolutionary history of Korean isolates of severe fever with thrombocytopenia syndrome virus from 2013-2016.

    abstract::Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV). Although SFTS originated in China, it is an emerging infectious disease with prevalence confirmed in Japan, Korea, and Vietnam. The full-length genomes of 51 Korean SFTSV isolates from 2013 to 2016 were sequenced, and the sequences wer...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-020-04733-0

    authors: Yun MR,Ryou J,Choi W,Lee JY,Park SW,Kim DW

    更新日期:2020-11-01 00:00:00

  • Protective efficacy in mice of a secreted form of recombinant dengue-2 virus envelope protein produced in baculovirus infected insect cells.

    abstract::We constructed a recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2E delta 102). The production, processing and transportation of the recombinant protein in baculovirus-infected Spodoptera frugiperda (Sf9) cells and its immunogenic prop...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01309465

    authors: Delenda C,Frenkiel MP,Deubel V

    更新日期:1994-01-01 00:00:00

  • Molecular characterization of field isolates of infectious bursal disease virus from three decades, 1987-2018, reveals a distinct genotypic subgroup in Vietnam.

    abstract::The complete nucleotide sequence of the viral protein 2 (VP2) ORF was determined for 26 Vietnamese infectious bursal disease isolates collected from clinical outbreaks in vaccinated flocks from 1987 to 2018 and two commercial vaccine specimens. These sequences were compared for molecular classification with 42 referen...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04287-w

    authors: Le XTK,Doan HTT,Do RT,Le TH

    更新日期:2019-08-01 00:00:00

  • The complete genome sequence of an El Amar isolate of plum pox virus (PPV) and its phylogenetic relationship to other PPV strains.

    abstract::The genomic sequence of an El Amar isolate of plum pox virus (PPV) from Egypt was determined by sequencing overlapping cDNA fragments. This is the first complete sequence of a member of the El Amar (EA) strain of PPV. The genome consists of 9791 nt, excluding a poly(A) tail at the 3' terminus. The complete nt sequence...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-005-0703-x

    authors: Myrta A,Varga A,James D

    更新日期:2006-06-01 00:00:00

  • Tomato dwarf leaf virus, a New World begomovirus infecting tomato in Argentina.

    abstract::Begomovirus infection is becoming a threat in fresh-market tomato in Argentina, where mixed infections with begomoviruses are common. The complete sequence of a begomovirus isolate infecting tomato sampled in Salta was molecularly characterized. Phylogenetic analysis showed that this virus isolate is closely related t...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-012-1355-2

    authors: Vaghi Medina CG,López Lambertini PM

    更新日期:2012-10-01 00:00:00

  • Epidermal hyperplasias of northern pike (Esox lucius) associated with herpesvirus and C-type particles.

    abstract::Northern pike from several locations in central Canada were observed to have two different types of hyperplastic epidermal lesions on the body and fins. One type of epidermal hyperplasia consisted of flat lesions, bluish-white in color with a granular or "gritty" appearance. Histological examination of this granular l...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01310815

    authors: Yamamoto T,Kelly RK,Nielsen O

    更新日期:1984-01-01 00:00:00

  • Identification and characterization of the interaction between viroplasm-associated proteins from two different plant-infecting reoviruses and eEF-1A of rice.

    abstract::A rice protein homologous to eukaryotic translation elongation factor 1A (eEF-1A) was found to interact with the Pns6 of rice ragged stunt virus (RRSV), the type member of the genus Oryzavirus, family Reoviridae, in yeast two-hybrid screening. The interaction between the rice protein, designated OseEF-1A, and RRSV Pns...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-013-1703-x

    authors: Songbai Z,Zhenguo D,Liang Y,Zhengjie Y,Kangcheng W,Guangpu L,Zujian W,Lianhui X

    更新日期:2013-10-01 00:00:00

  • Characterization of the complete genome of ribgrass mosaic virus isolated from Plantago major L. from New Zealand and Actinidia spp. from China.

    abstract::The complete genomes of tobamovirus isolates from Plantago major L. from New Zealand (NZ-439), Plantago sp. from Germany (Kons 1105), Actinidia chinensis (Actinidia-AC) and A. deliciosa (Actinidia-AD) from China were sequenced and compared to previously published tobamovirus genomes. Their genome organization and phyl...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-012-1292-0

    authors: Chavan RR,Cohen D,Blouin AG,Pearson MN

    更新日期:2012-07-01 00:00:00

  • Molecular detection and characterization of genotype 1 bovine leukemia virus from beef cattle in the traditional sector in Zambia.

    abstract::Whilst bovine leukemia virus (BLV) causes considerable economic losses to the dairy industry worldwide, information on its molecular epidemiology and economic impact in beef cattle is limited. Here, blood from 880 animals from Zambia's major cattle-rearing provinces was screened for BLV by nested PCR. Positive pools w...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04350-6

    authors: Phiri MM,Kaimoyo E,Changula K,Silwamba I,Chambaro HM,Kapila P,Kajihara M,Simuunza M,Muma JB,Pandey GS,Takada A,Mweene AS,Chitanga S,Simulundu E

    更新日期:2019-10-01 00:00:00

  • Nucleotide sequence analysis of Vietnamese highly pathogenic porcine reproductive and respiratory syndrome virus from 2013 to 2014 based on the NSP2 and ORF5 coding regions.

    abstract::A total of 34 highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) strains isolated from Vietnam during 2013-2014 were sequenced and analyzed. A partial sequence of ORF1a corresponding to the nonstructural protein 2 (Nsp2) coding region and the full sequence of open reading frame 5 (ORF5) g...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-015-2699-1

    authors: Do DT,Park C,Choi K,Jeong J,Nguyen TT,Le DT,Vo KM,Chae C

    更新日期:2016-03-01 00:00:00

  • c-Jun integrates signals from both MEK/ERK and MKK/JNK pathways upon vaccinia virus infection.

    abstract::Usurpation of the host's signalling pathways is a common strategy employed by viruses to promote their successful replication. Here we show that infection with the orthopoxvirus vaccinia virus (VACV) leads to sustained stimulation of c-Jun activity during the entire infective cycle. This stimulation is temporally regu...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-017-3446-6

    authors: Leite FGG,Torres AA,De Oliveira LC,Da Cruz AFP,Soares-Martins JAP,Pereira ACTC,Trindade GS,Abrahão JS,Kroon EG,Ferreira PCP,Bonjardim CA

    更新日期:2017-10-01 00:00:00

  • Nucleotide sequence and infectious transcripts from a full-length cDNA clone of the carmovirus Melon necrotic spot virus.

    abstract::We have studied the biological and molecular characteristics of a MNSV isolate collected in Spain (MNSV-Malpha5) and generated a full-length cDNA clone from which infectious RNA transcripts can be produced. The host range of MNSV-Malpha5 appeared to be limited to cucurbits and did not differ from that of MNSV-Dutch [4...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-002-0927-y

    authors: Díaz JA,Bernal JJ,Moriones E,Aranda MA

    更新日期:2003-03-01 00:00:00

  • Comparison of the nucleoprotein genes of a chicken and a mink influenza A H 10 virus.

    abstract::The base sequences of the coding region of the nucleoprotein (NP) genes of two H 10 influenza A viruses, one avian (virus N) and one mink virus, have been determined by primer extension. When the NP genes and the NP sequences derived from the only open reading frame of the two H 10 viruses were compared with those of ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01319816

    authors: Reinhardt U,Scholtissek C

    更新日期:1988-01-01 00:00:00

  • Characterization of cell lines derived from hamster tumors induced with the BK virus.

    abstract::Some of the properties of three continuous cell lines derived from BK virus-induced hamster tumors were examined. The cell lines had in vitro growth characteristics of transformed cells. Morphologically most of the cells were fibroblastic, but multinucleated giant cells were also common. Ultrastructurally all three ce...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01318002

    authors: Sten M,Tolonen A,Pitko VM,Nevalainen T,Mäntyjärvi RA

    更新日期:1976-01-01 00:00:00

  • Evidence for the presence of a genome-linked protein in infectious flacherie virus.

    abstract::The genomic RNA of infectious flacherie virus (IFV), an insect picornavirus, was shown to contain a covalently attached substance which can be labeled with 125I-Bolton and Hunter reagent. This substance was found to be a protein covalently linked to the virus genome, because it cosedimented and was copurified with the...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01317378

    authors: Hashimoto Y,Watanabe A,Kawase S

    更新日期:1986-01-01 00:00:00

  • Phylogenetic and recombination analysis of rice black-streaked dwarf virus segment 9 in China.

    abstract::Rice black-streaked dwarf virus (RBSDV) is an economically important virus that causes maize rough dwarf disease and rice black-streaked dwarf disease in East Asia. To study RBSDV variation and recombination, we examined the segment 9 (S9) sequences of 49 RBSDV isolates from maize and rice in China. Three S9 recombina...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-014-2291-0

    authors: Zhou Y,Weng JF,Chen YP,Liu CL,Han XH,Hao ZF,Li MS,Yong HJ,Zhang DG,Zhang SH,Li XH

    更新日期:2015-04-01 00:00:00

  • Effect of gene constellation and postreassortment amino acid change on the phenotypic features of H5 influenza virus reassortants.

    abstract::Reassortants between a low-pathogenic avian influenza virus strain A/Duck/Primorie/2621/2001 (H5N2) and a high-yield human influenza virus strain A/Puerto Rico/8/34 (H1N1) were generated, genotyped and analyzed with respect to their yield in embryonated chicken eggs, pathogenicity for mice, and immunogenicity. A reass...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-006-0931-8

    authors: Rudneva IA,Timofeeva TA,Shilov AA,Kochergin-Nikitsky KS,Varich NL,Ilyushina NA,Gambaryan AS,Krylov PS,Kaverin NV

    更新日期:2007-01-01 00:00:00

  • Complete genome sequence of datura leaf curl virus, a novel begomovirus infecting Datura innoxia in Sudan, related to begomoviruses causing tomato yellow leaf curl disease.

    abstract::Several species in the genus Datura (family Solanaceae) are hosts for begomoviruses (family Geminiviridae), both in the New World and the Old World. Here, we report the genome characterization of two isolates of a novel Old World monopartite begomovirus infecting Datura innoxia in Sudan, which we propose to be named "...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-017-3574-z

    authors: Mohammed HS,El Siddig MA,El Hussein AA,Navas-Castillo J,Fiallo-Olivé E

    更新日期:2018-01-01 00:00:00

  • The complete genomic sequence of a second novel partitivirus infecting Ustilaginoidea virens.

    abstract::The bisegmented genome of a putative double-stranded (ds) RNA virus from Ustilaginoidea virens was sequenced and analyzed. The larger genomic segment of 2112 bp encodes a putative RNA-dependent RNA polymerase (RdRp, 628 aa), and the smaller one of 2082 bp encodes a putative coat protein (CP) of 539 aa. The 5' untransl...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-014-1991-9

    authors: Jiang Y,Luo C,Jiang D,Li G,Huang J

    更新日期:2014-07-01 00:00:00

  • Retroviral properties inherent to viral erythrocytic infection in sea bass.

    abstract::The characterization of the aetiological agent of viral erythrocytic infection (VEI) of sea bass suggests a retroviral origin of the disease. RNA from viral erythrocytic infection virus (VEIV) and DNA from blood and organs of VEI-affected fish hybridized to a specific retrovirus cDNA probe. Sequences homologous to ret...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01309960

    authors: Pintó RM,Ribes E,Jofre J,Bosch A

    更新日期:1995-01-01 00:00:00