Abstract：
BACKGROUND:To review the outcomes of the patients who undergo orbital exenteration for malignancy. METHODS:A retrospective review of patients who underwent orbital exenteration performed at Royal Prince Alfred and Concord Hospitals between 1990 and 2008. RESULTS:A total of 38 patients were identified. The most common malignancies were squamous cell carcinoma (14 cutaneous and five mucosal origin), basal cell carcinoma (12 cutaneous) and melanoma (five patients). Orbital invasion was the main indication for orbital exenteration. Additional procedures were performed in 29 (76%) patients at the time of exenteration, including craniotomies in eight patients and maxillectomy in 15 patients. Flap reconstructions were required in 35 (92%) patients, including 33 free flap repairs and two local flap repairs. Post-operative complications included cerebrospinal fluid leak (16%) and wound-related complications (13%). The disease-specific survival rate was 97% at 1 year and 92% at 5 years. The local control rate was 83% at 1 year and 55% at 5 years. Fifty per cent of patient mortality and 63% of local recurrence occurred within the first post-operative year. CONCLUSIONS:In this series, locoregional control and survival were high, suggesting that aggressive surgical measures such as orbital exenteration are not unreasonable in well-selected patients. Free flap reconstruction is a reliable reconstructive technique which may reduce major complications. The first post-operative year is the most important period when monitoring for recurrence.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Kuo CH,Gao K,Clifford A,Shannon K,Clark Jdoi
10.1111/j.1445-2197.2010.05592.xsubject
Has Abstractpub_date
2011-05-01 00:00:00pages
326-30issue
5eissn
1445-1433issn
1445-2197journal_volume
81pub_type
杂志文章abstract：:Macrophages, derived from circulating monocytes, are located within virtually all adult tissues. There, these specialized cells adopt tissue-specific functions that are important for normal tissue homeostasis and response to physiological challenges. Increasing evidence suggests that macrophages play a role in the nor...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2008.04531.x
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Although patterns of return of bowel function (ROBF) following colorectal surgery with enhanced recovery after surgery (ERAS) programmes have been well delineated, regular morphine use is uncommon. This study describes the patterns of post-operative nausea and vomiting (PONV) and ROBF in this context. METHO...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.13290
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:The ability to predict the behaviour of breast cancer from its dimensions allows the clinician to inform a woman about the absolute benefits of adjuvant therapies or further surgery to control her disease. Tumour size and grade are independent predictors of nodal disease. This study aims to generate a tool, ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2006.03918.x
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:Flail chest is a serious injury in trauma with a significant mortality rate, and long-term pain and disability. Traditionally, management has consisted of internal pneumatic splinting, leading to prolonged periods of mechanical ventilation, and its attendant complications. The aim of this study was to assess...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2009.05104.x
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:This study aimed to explore the effects of early antiplatelet therapy (APT) for portal vein thrombosis (PVT) in patients with cirrhotic portal hypertension after splenectomy with gastro-oesophageal devascularization. METHODS:We retrospectively analysed 139 patients who underwent splenectomy with gastro-oeso...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.14395
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Many attempts have been made to determine ways of decreasing the negative laparotomy rate after a clinical diagnosis of acute appendicitis. The aim of the present study was to determine the effectiveness of serum interleukin-6 (IL-6) concentration in the diagnosis of appendicitis, and in the prevention of no...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1445-2197.2002.02516.x
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:Thyroid nodules are common and the principal method of diagnosis is fine-needle aspiration cytology (FNAC). METHODS:To determine the value of FNAC in the diagnosis of thyroid nodules, thyroid cytology of 253 patients with definitive histology after surgery was analyzed from 1992 to 2002. FNAC was correlated...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1445-1433.2003.02670.x
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:The ability to tolerate a tourniquet is often the limiting factor to elective and emergent procedures of the upper limb performed under local anaesthesia. This study aims to demonstrate that upper limb tourniquets are more predictably and better tolerated when inflated to 200 mmHg than to the traditional inf...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12532
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Oncology literature is increasingly recognizing prevalence of second primary cancers including several longitudinal studies showing an increased risk of colorectal cancer following a prostate cancer diagnosis. A retrospective study was conducted to examine the relationship between prior prostate cancer diagn...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12136
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:In a rural centre with limited resources and no endoscopic retrograde cholangiopancreatography facilities, a prospective cohort study was established to compare policies of routine and selective intraoperative cholangiography (IOC) in order to develop a local protocol. METHODS:Patients undergoing laparoscop...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2005.03393.x
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:Readability indices have been developed based on sentence length and the use of long words. One such measure is the Reading Ease Scale developed by Rudolf Flesch. Texts that are easy to read have high scores: texts with scores below 30 are similar to legal contracts. This study uses Flesch scores to evaluate...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2006.03651.x
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:The surgical cure rate for primary hyperparathyroidismis greater than 95%. For those who have recurrent or persistent disease, preoperative localization improves reoperation success rates. Selective parathyroid venous sampling (SPVS) for intact parathyroid hormone is particularly useful when non-invasive loc...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1445-2197.2003.02678.x
更新日期：2003-10-01 00:00:00
abstract：BACKGROUND:Incidence of the gastro-oesophageal junction adenocarcinoma is increasing. Siewert's classification subdivides junctional adenocarcinomas anatomically. Cytokeratin (CK) 7 and 20 immunophenotypes differentiate Barrett's intestinal metaplasia (IM) from gastric IM. Comparing CK immunostaining with Siewert's cla...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04147.x
更新日期：2007-07-01 00:00:00
abstract：:Recent advances in understanding of the biology of appendicitis are reviewed. Immunological aspects are discussed in the setting of a changing microbiome. Implications for practice are summarized. ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,评审
doi：10.1111/ans.16018
更新日期：2020-06-08 00:00:00
abstract：BACKGROUND:Sore throat is not an uncommon complaint following general anaesthesia (GA) with endotracheal intubation. It has been a source of considerable discomfort particularly in those patients who had thyroid surgery. Driven by the increased number of patients with post-intubation sore throat following thyroid surge...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1445-1433.2001.02230.x
更新日期：2001-11-01 00:00:00
abstract：BACKGROUND:Metabolic acidosis is frequently observed in perioperative patients, especially those who undergo major surgery. The aim of this study was to evaluate the factors related to post-operative metabolic acidosis and to attempt to identify the clinical effect of metabolic acidosis following major abdominal surger...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2012.06235.x
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Although several growth factors are known to be essential for liver regeneration, the role of gastrin remains controversial. METHODS:Liver regeneration was examined in wild-type (WT) and gastrin-deficient (gastrin KO) mice at days 2 and 10 after partial (40%) hepatectomy by measurement of liver weight. Hepa...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04360.x
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Pain is a personal, subjective experience. In the postoperative period, pain may be influenced by patient, pharmacological and environmental factors. In surgery the aim is to reduce pain in this period by educating patients and using adequate analgesia. The aim of the present study was to assess the effect o...
journal_title：ANZ journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1046/j.1445-1433.2003.02576.x
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Recent follow-up studies have demonstrated significant improvement in overall survival as well as survival with native liver following geographic centralization of services to three centres in the UK. However, this model has not been replicated in countries with relatively low population density such as Aust...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12522
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:The correlation of post-operative serum albumin level with the occurrence of anastomotic leakage (AL) in oesophageal squamous cell carcinoma (ESCC) remains unclear. The aim of this study was to evaluate the impact of post-operative serum albumin level on AL after transthoracic oesophagectomy. METHODS:Patien...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.16406
更新日期：2020-11-05 00:00:00
abstract：BACKGROUND:Interleukin-12 (IL-12) has been shown to enhance the cytotoxic activity of NK cells and CTL. IL-12 also acts as a growth factor for activated NK, T and NKT cells. The soluble HLA class I (sHLA-I) has been reported to bind a killer-cell inhibitory receptor, which is expressed on the NK cell, and its signals i...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2009.04947.x
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:To extract from the biomedical published reports, the effects of hyperbaric oxygen (HBO) on inflammatory disease, in particular acute pancreatitis. METHODS:This review will explain these effects and evaluate potential mechanisms of action of HBO in acute pancreatitis. A Medline/PubMed search (January 1966 t...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,评审
doi：10.1111/j.1445-2197.2006.03793.x
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Surgical clerkships facilitate development of knowledge and competency, but their structure and content vary. Establishment of new medical schools and raising student numbers are new challenges to the provision of standardized surgical teaching across Australasian medical schools. A survey was conducted to i...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2010.05524.x
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:An enhanced fracture healing response has been reported in patients with traumatic brain injury (TBI). This has been attributed to circulating humoral factors that are thought to be proteins produced and released by the injured brain. However, these factors remain unknown. The aim of this study was to identi...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2010.05268.x
更新日期：2010-07-01 00:00:00
abstract：:Mucinous appendiceal neoplasms (MANs) are rare tumours and the primary cause of pseudomyxoma peritonei. These tumours have a much more benign course than typical colorectal cancers, generally growing for many years before giving any clinical signs. The spectrum of presentations, tumour stages and the underlying cytolo...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,评审
doi：10.1111/ans.16185
更新日期：2020-08-05 00:00:00
abstract：:Acute colonic pseudo-obstruction (ACPO) and chronic intestinal pseudo-obstruction (CIPO) are distinct clinical entities in which patients present similarly with symptoms of a mechanical obstruction without an occlusive lesion. Unfortunately, they also share the issues related to a delay in diagnosis, including inappro...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,评审
doi：10.1111/ans.13148
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Desmoplastic melanoma (DM) is a rare subtype of cutaneous malignant melanoma reported to have a high local recurrence rate with surgical excision alone. The incidence of regional and distant metastasis is considered to be lower than traditional cutaneous melanoma, warranting more aggressive treatment of loca...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2008.04436.x
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:Appendicectomy remains the most common abdominal emergency procedure performed by surgeons. We reviewed appendicectomies for the calendar years 1999 and 2009 to assess any changes in the referral, presentation and management at a tertiary paediatric institution. METHODS:We performed a retrospective chart re...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2012.06168.x
更新日期：2012-09-01 00:00:00
abstract：:Total thyroidectomy is the treatment of choice for clinically significant papillary thyroid cancer (PTC); however, 10-15% develop palpable local recurrence in the cervical lymph nodes. Metastases in the cervical lymph nodes account for 75% of loco-regional recurrence and up to 50% of these patients eventually die of t...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04019.x
更新日期：2007-04-01 00:00:00
abstract：:Chronic constipation is a common condition in both adults and children. Children with chronic constipation frequently have symptoms that continue into adulthood. In the second part of the review we describe advances in the identification of abnormalities in the control of motility. The role of neurotransmitters in bot...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,评审
doi：10.1111/j.1445-1433.2004.03202.x
更新日期：2004-10-01 00:00:00
