Impact of an HPV6/11/16/18 L1 virus-like particle vaccine on progression to cervical intraepithelial neoplasia in seropositive women with HPV16/18 infection.

abstract：:The role of chemotherapy in influencing tumor-specific immunity to a mouse mammary adenocarcinoma was investigated. By studying different stages of tumor growth we were able to identify several factors important to drug-induced tumor regression: (1) antibody response, (2) delayed hypersensitivity, (3) sensitivity of t...

journal_title：International journal of cancer

authors： Radov LA,Korn JH,Haskill JS

更新日期：1976-11-15 00:00:00

abstract：:The studies reported here explore the relationship between tumor-specific transplantation antigens (TSTA) and (1) the expression of serologically defined specificities, and (2) the immunogenicity of H-2K- or H-2D-determined alloantigens on methylcholanthrene (MCA)-induced murine fibrosarcomas. Expression of H-2K and H...

journal_title：International journal of cancer

authors： Chauvenet PH,Smith RT

更新日期：1978-07-15 00:00:00

abstract：:Circulating tumor DNA (ctDNA) is a new circulating tumor biomarker which might be used as a prognostic biomarker in a way similar to circulating tumor cells (CTCs). Here, we used the high prevalence of TP53 mutations in triple negative breast cancer (TNBC) to compare ctDNA and CTC detection rates and prognostic value ...

journal_title：International journal of cancer

authors： Madic J,Kiialainen A,Bidard FC,Birzele F,Ramey G,Leroy Q,Rio Frio T,Vaucher I,Raynal V,Bernard V,Lermine A,Clausen I,Giroud N,Schmucki R,Milder M,Horn C,Spleiss O,Lantz O,Stern MH,Pierga JY,Weisser M,Lebofsky R

更新日期：2015-05-01 00:00:00

abstract：:Major etiologic factors associated with human hepatocellular carcinomas (HCCs) include infection with hepatitis C (HCV) and hepatitis B virus (HBV), excess alcohol intake and aflatoxin B(1) exposure. While the G-->T p53 mutation at codon 249 has been identified as a genetic hallmark of HCC caused by aflatoxin B(1), th...

journal_title：International journal of cancer

authors： Edamoto Y,Hara A,Biernat W,Terracciano L,Cathomas G,Riehle HM,Matsuda M,Fujii H,Scoazec JY,Ohgaki H

更新日期：2003-09-01 00:00:00

abstract：:Primary rabbit kidney cells were transformed by BKV(MM), a papovavirus isolated from the urine of a child with the Wiskott-Aldrich syndrome. The transformed cells contained BK T-antigen, but no antigen that reacted with SV40 U-antiserum. The transformed cells failed to produce tumors in nude mice, and BKV (MM) was not...

journal_title：International journal of cancer

authors： Mason DH Jr,Takemoto KK

更新日期：1977-03-15 00:00:00

abstract：:The effect that polymorphonuclear leukocytes (PMN) may have on the metastatic colonization of tumor cells is controversial: some laboratories have reported that PMN can inhibit metastasis whereas others have shown an augmentation effect. We have exploited our finding that a particular fibrosarcoma (BMT-11) transplante...

journal_title：International journal of cancer

authors： Ishikawa M,Koga Y,Hosokawa M,Kobayashi H

更新日期：1986-06-15 00:00:00

abstract：:Rapid growth of residual tumor after partial hepatectomy has been observed during the period of liver regeneration in children with malignant embryonal hepatoblastoma. The aim of this study was to elucidate the role of hepatocyte growth-factor-scatter factor (HGF-SF) in this phenomenon. Markedly increased serum levels...

journal_title：International journal of cancer

authors： von Schweinitz D,Faundez A,Teichmann B,Birnbaum T,Koch A,Hecker H,Glüer S,Fuchs J,Pietsch T

更新日期：2000-01-15 00:00:00

abstract：:The characteristics of tumor antigens of the transplantation type, TATA, were studied in a series of methylcholanthrene-induced sarcomas in pedigreed BALB/cAN mice. Each of the six sarcomas exhibited unique TATA when assayed for tumor rejection in syngeneic hosts. In three instances, however, in sarcomas CI-I, CII-5 a...

journal_title：International journal of cancer

authors： Law LW

更新日期：1980-02-15 00:00:00

abstract：:The relationship between the biomarker of vitamin D status, 25(OH)D, and the risk for colorectal neoplasia is suggestive but equivocal. Questions remain regarding whether there are differential associations between 25(OH)D and colorectal adenoma by gender, colorectal subsite or features of baseline and recurrent adeno...

journal_title：International journal of cancer

authors： Jacobs ET,Hibler EA,Lance P,Sardo CL,Jurutka PW

更新日期：2013-12-15 00:00:00

abstract：:Polymorphisms in nucleotide oligomerization domain 2 gene (NOD2) have been associated with increased susceptibility to Crohn's disease. Recently, possible association of the NOD2 variants R702W, G908R and 3020insC with colorectal cancer (CRC) has been studied among Polish, Greek, Finnish and New Zealand Caucasian CRC ...

journal_title：International journal of cancer

authors： Tuupanen S,Alhopuro P,Mecklin JP,Järvinen H,Aaltonen LA

更新日期：2007-07-01 00:00:00

abstract：:Screening for cancer has to be carefully organized for maximum effectiveness, and introduced in full understanding of the natural history of the disease. There are major potential harms as well as benefits from screening. The current state of art for breast, cervix and prostate cancer screening is reviewed, only for b...

journal_title：International journal of cancer

authors： Miller AB

更新日期：2010-03-01 00:00:00

abstract：:We have studied the occurrence and association of 11q deletions with other chromosomal imbalances in Stage 4 neuroblastomas. To this purpose we have performed comparative genomic hybridization (CGH) analysis on 50 Stage 4 neuroblastomas and these data were analyzed together with those from 33 previously published case...

journal_title：International journal of cancer

authors： Plantaz D,Vandesompele J,Van Roy N,Lastowska M,Bown N,Combaret V,Favrot MC,Delattre O,Michon J,Bénard J,Hartmann O,Nicholson JC,Ross FM,Brinkschmidt C,Laureys G,Caron H,Matthay KK,Feuerstein BG,Speleman F

更新日期：2001-03-01 00:00:00

abstract：:Experimental studies have suggested that the biosynthesis of arachidonic acid-derived eicosanoids such as prostaglandin E2 via the cyclo-oxygenase pathway may play a significant role in supporting cell proliferation in human prostate cancer cell lines. However, the aetiological significance of this for clinical prosta...

journal_title：International journal of cancer

authors： Norrish AE,Jackson RT,McRae CU

更新日期：1998-08-12 00:00:00

abstract：:Colorectal cancer (CRC) represents the second most common cause of cancer mortality in the western world. The tumors frequently show metastatic spread which affects different organs such as lymph nodes, liver and lungs. Although the pattern of spread may vary, the initial step usually involves dissemination to regiona...

journal_title：International journal of cancer

authors： Sundlisaeter E,Dicko A,Sakariassen PØ,Sondenaa K,Enger PØ,Bjerkvig R

更新日期：2007-10-01 00:00:00

abstract：:Leukocyte-transforming agents were isolated in baboon leukocytes inoculated with oral excretions from immunosuppressed chimpanzees. The transformed lymphoblasts had B cell surface markers and harbored herpes-type virus particles; 5-10% of the cells contained cytoplasmic antigens reactive with Epstein-Barr virus (EBV)-...

journal_title：International journal of cancer

authors： Gerber P,Kalter SS,Schidlovsky G,Peterson WD Jr,Daniel MD

更新日期：1977-09-15 00:00:00

abstract：:Secreted frizzled-related proteins (SFRPs) are antagonists of the Wnt signaling pathway whose epigenetic downregulation have been shown to be involved in hepatocarcinogenesis. However, dysregulation of SFRPs induced by hepatitis B virus (HBV) X protein (HBx) has never been studied in HBV-related hepatocellular carcino...

journal_title：International journal of cancer

authors： Xie Q,Chen L,Shan X,Shan X,Tang J,Zhou F,Chen Q,Quan H,Nie D,Zhang W,Huang AL,Tang N

更新日期：2014-08-01 00:00:00

abstract：:The results of a survey of a population with a high incidence of oral and oesophageal cancer are presented. The population under study appears to have several epidemiologic characteristics, some of which may be associated with a high incidence of oral and oesophageal cancer. A remarkably high proportion (41%) of the m...

journal_title：International journal of cancer

authors： Zaridze DG,Blettner M,Trapeznikov NN,Kuvshinov JP,Matiakin EG,Poljakov BP,Poddubni BK,Parshikova SM,Rottenberg VI,Chamrakulov FS

更新日期：1985-08-15 00:00:00

abstract：:The molecular mechanisms underlying the genesis and progression of oligodendroglial tumors are poorly understood, since only restricted information on loss of heterozygosity from isolated cases is available. The commonest alterations appear to involve deletion of 1p and 19q, while loss of heterozygosity for 9p, chromo...

journal_title：International journal of cancer

authors： Bello MJ,Leone PE,Vaquero J,de Campos JM,Kusak ME,Sarasa JL,Pestaña A,Rey JA

更新日期：1995-06-22 00:00:00

abstract：:Risk factors for prostate cancer could differ for various sub-groups, such as for "aggressive" and "non-aggressive" cancers or by grade or stage. Determinants of mortality could differ from those for incidence. Using data from the Health Professionals Follow-Up Study, we re-examined 10 factors (cigarette smoking histo...

journal_title：International journal of cancer

authors： Giovannucci E,Liu Y,Platz EA,Stampfer MJ,Willett WC

更新日期：2007-10-01 00:00:00

abstract：:We screened 29 human esophageal squamous cell carcinoma (ESC) cell lines for mutations of the p53 gene through all coding exons and exon-intron junctions. Mutations were found in 22 cell lines (76%), consisting of 20 single-base substitutions, 2 small deletions and 1 single-base insertion. Out of 20 single-base substi...

journal_title：International journal of cancer

authors： Tanaka H,Shibagaki I,Shimada Y,Wagata T,Imamura M,Ishizaki K

更新日期：1996-01-26 00:00:00

abstract：:Cancer is associated with epigenetic (i.e., histone hypoacetylation) and metabolic (i.e., aerobic glycolysis) alterations. Levels of N-acetyl-L-aspartate (NAA), the primary storage form of acetate in the brain, and aspartoacylase (ASPA), the enzyme responsible for NAA catalysis to generate acetate, are reduced in glio...

journal_title：International journal of cancer

authors： Tsen AR,Long PM,Driscoll HE,Davies MT,Teasdale BA,Penar PL,Pendlebury WW,Spees JL,Lawler SE,Viapiano MS,Jaworski DM

更新日期：2014-03-15 00:00:00

abstract：:A novel cell culture system is reported for the growth of ovarian tumors. Two approaches were developed to isolate tumor cells, one for ovarian carcinomas and the other for benign cystomas or borderline cystadenomas, which yield virtually pure tumor-cell clusters. The plating efficiency exceeded 10% in approximately 8...

journal_title：International journal of cancer

authors： Balconi G,Broggini M,Erba E,D'Incalci M,Colombo N,Mangioni C,Bertolero F

更新日期：1988-06-15 00:00:00

abstract：:It is considered that fruit and vegetable (F&V) protect against oesophagus and gastric cancer (GC). However, 2 recent meta-analyses suggest that the strength of association on GC seems to be weaker for vegetables than for fruit and weaker in cohort than in case-control studies. No evidence exists from cohort studies a...

journal_title：International journal of cancer

authors： González CA,Pera G,Agudo A,Bueno-de-Mesquita HB,Ceroti M,Boeing H,Schulz M,Del Giudice G,Plebani M,Carneiro F,Berrino F,Sacerdote C,Tumino R,Panico S,Berglund G,Simán H,Hallmans G,Stenling R,Martinez C,Dorronsoro M

更新日期：2006-05-15 00:00:00

abstract：:To monitor recent trends in oral and pharyngeal cancer mortality in 38 European countries, we analyzed data provided by the World Health Organization over the period 1975-2004. Joinpoint analysis was used to identify significant changes in trends. In the European Union (EU), male mortality rates rose by 2.1% per year ...

journal_title：International journal of cancer

authors： Garavello W,Bertuccio P,Levi F,Lucchini F,Bosetti C,Malvezzi M,Negri E,La Vecchia C

更新日期：2010-07-01 00:00:00

abstract：:In a previous study, we showed that targeted delivery of bovine liver catalase to hepatocytes by direct galactosylation augmented the inhibitory effect of the enzyme on experimental hepatic metastasis of colon carcinoma cells (unpublished data). Here, we examined the ability of catalase to inhibit tumor metastasis to ...

journal_title：International journal of cancer

authors： Nishikawa M,Tamada A,Kumai H,Yamashita F,Hashida M

更新日期：2002-05-20 00:00:00

abstract：:The suppressive activity of regulatory T cells (Treg) has been implicated as an important factor limiting immune mediated destruction of tumor cells. However, not much is known about the presence and function of Treg within tumors. Here we show in a syngeneic murine glioma model a time-dependent accumulation of CD4+Fo...

journal_title：International journal of cancer

authors： Grauer OM,Nierkens S,Bennink E,Toonen LW,Boon L,Wesseling P,Sutmuller RP,Adema GJ

更新日期：2007-07-01 00:00:00

abstract：:Data on the incidence of childhood cancer in Queensland during the 10-year period 1979-88 are presented. During this period, 786 cases were registered. The average annual crude and age-standardized (to the world population) incidence rates for both sexes were 12.63 and 13.30 per 100,000 respectively. The incidence of ...

journal_title：International journal of cancer

authors： McWhirter WR,Petroeschevsky AL

更新日期：1990-06-15 00:00:00

abstract：:In the Japanese atomic bomb survivors, risk of lung cancer has been shown to increase with greater acute exposure to ionizing radiation. Although similar findings have been observed in populations exposed to low-dose, protracted radiation, such studies lack information on cigarette smoking history, a potential confoun...

journal_title：International journal of cancer

authors： Velazquez-Kronen R,Gilbert ES,Linet MS,Moysich KB,Freudenheim JL,Wactawski-Wende J,Simon SL,Cahoon EK,Alexander BH,Doody MM,Kitahara CM

更新日期：2020-12-01 00:00:00

abstract：:miRNAs have emerged as post-transcriptional regulators that are critically involved in the pathogenesis of a number of human cancers. Cdc42, one of the best characterized members of the Rho GTPase family, is found to be up-regulated in several types of human tumors and has been implicated in cancer initiation and prog...

journal_title：International journal of cancer

authors： Liu M,Lang N,Qiu M,Xu F,Li Q,Tang Q,Chen J,Chen X,Zhang S,Liu Z,Zhou J,Zhu Y,Deng Y,Zheng Y,Bi F

更新日期：2011-03-15 00:00:00

abstract：:The mouse anti-id MAb MK2-23 bears the internal image of the antigenic determinant defined by anti-HMW-MAA MAb 763.74. Active specific immunotherapy with anti-id MAb MK2-23 is associated with a statistically significant prolongation of survival in patients with malignant melanoma. Characterization of the immune respon...

journal_title：International journal of cancer

authors： Kageshita T,Hirai S,Ono T,Ferrone S

更新日期：1995-01-27 00:00:00