Abstract:
AIM:The LUCAS™ device has been shown to improve organ perfusion during cardiac arrest in experimental studies. In this pilot study the aim was to compare short-term survival between cardiopulmonary resuscitation (CPR) performed with mechanical chest compressions using the LUCAS™ device and CPR performed with manual chest compressions. The intention was to use the results for power calculation in a larger randomised multicentre trial. METHODS:In a prospective pilot study, from February 1, 2005, to April 1, 2007, 149 patients with out-of hospital cardiac arrest in two Swedish cities were randomised to mechanical chest compressions or standard CPR with manual chest compressions. RESULTS:After exclusion, the LUCAS and the manual groups contained 75 and 73 patients, respectively. In the LUCAS and manual groups, spontaneous circulation with a palpable pulse returned in 30 and 23 patients (p = 0.30), spontaneous circulation with blood pressure above 80/50 mm Hg remained for at least 5 min in 23 and 19 patients (p = 0.59), the number of patients hospitalised alive >4h were 18 and 15 (p = 0.69), and the number discharged, alive 6 and 7 (p = 0.78), respectively. CONCLUSIONS:In this pilot study of out-of-hospital cardiac arrest patients we found no difference in early survival between CPR performed with mechanical chest compression with the LUCAS™ device and CPR with manual chest compressions. Data have been used for power calculation in a forthcoming multicentre trial.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Smekal D,Johansson J,Huzevka T,Rubertsson Sdoi
10.1016/j.resuscitation.2011.01.032subject
Has Abstractpub_date
2011-06-01 00:00:00pages
702-6issue
6eissn
0300-9572issn
1873-1570pii
S0300-9572(11)00122-5journal_volume
82pub_type
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