Implementation of Fowler's method for end-tidal air sampling.

abstract：:Staphylococcus aureus (S. aureus) is a common bacterium infecting children with cystic fibrosis (CF). Since current detection methods are difficult to perform in children, there is need for an alternative. This proof of concept study investigates whether breath profiles can discriminate between S. aureus infected and ...

journal_title：Journal of breath research

authors： Neerincx AH,Geurts BP,van Loon J,Tiemes V,Jansen JJ,Harren FJ,Kluijtmans LA,Merkus PJ,Cristescu SM,Buydens LM,Wevers RA

更新日期：2016-11-30 00:00:00

abstract：:Reactive oxygen species are associated with tissue inflammation and injury. Our laboratory has demonstrated that ethane, a stable product of lipid peroxidation, in exhaled breath can be used to measure total body oxidative stress. Herein patients were studied who underwent outpatient surgery, laproscopic bilateral tub...

journal_title：Journal of breath research

authors： Brown RH,Risby TH

更新日期：2009-03-01 00:00:00

abstract：:Despite recent progress in Critical Care Medicine, sepsis is still a major medical problem with a high rate of mortality and morbidity especially in intensive care units. Oxidative stress induced by inflammation associated with sepsis causes degradation of heme protein, increases microsomal free heme content, promotes...

journal_title：Journal of breath research

authors： Morimatsu H,Takahashi T,Matsusaki T,Hayashi M,Matsumi J,Shimizu H,Matsumi M,Morita K

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The analysis of volatile organic compounds (VOCs) in breath allows non-invasive investigations of diseases. Animal studies are conducted as a model to perform research of VOCs and their relation to diseases. In large animal models ruminants were often used as experimental targets. The effect of their physiol...

journal_title：Journal of breath research

authors： Oertel P,Küntzel A,Reinhold P,Köhler H,Schubert JK,Kolb J,Miekisch W

更新日期：2018-05-14 00:00:00

abstract：:Exhaled NO (FE(NO)) measurements have been utilized as a marker to diagnose asthma as well as a non-invasive tool for monitoring airway inflammation and the response to anti-inflammatory medications. One area where this non-invasive monitoring may be helpful is for asthmatic athletes as they train for competitive even...

journal_title：Journal of breath research

authors： Grob NM,Laskowski D,Dweik RA

更新日期：2008-09-01 00:00:00

abstract：:Based on the adsorption of analytes in the sampling loop, a time-resolved dynamic dilution introduction method was developed for negative ion mobility spectrometry to continuously monitor end-tidal propofol without other sample pre-separation. The dynamic dilution characteristics of propofol and moisture in the Teflon...

journal_title：Journal of breath research

authors： Zhou Q,Li E,Wang Z,Gong Y,Wang C,Guo L,Li H

更新日期：2015-01-05 00:00:00

abstract：:Robust methods for breath sampling and analysis are required for potential clinical applications. We have evaluated an improved sampling and experimental design, assessing instrumental and biological variability within and across breath measurements. Calibration curves for selected relevant volatile organic compounds...

journal_title：Journal of breath research

authors： Basanta M,Ibrahim B,Douce D,Morris M,Woodcock A,Fowler SJ

更新日期：2012-06-01 00:00:00

abstract：:Microbial cultures and/or microbial associated diseases often have a characteristic smell. Volatile organic compounds (VOCs) are produced by all microorganisms as part of their normal metabolism. The types and classes of VOC produced is wide, including fatty acids and their derivatives (e.g. hydrocarbons, aliphatic al...

journal_title：Journal of breath research

authors： Thorn RM,Greenman J

更新日期：2012-06-01 00:00:00

abstract：:The lung just like all other organs is affected by age. The lung matures by the age of 20 and age-related changes start around middle age, at 40-50 years. Exhaled nitric oxide (FENO) has been shown to be age, height and gender dependent. We hypothesize that the nitric oxide (NO) parameters alveolar NO (CANO), airway f...

journal_title：Journal of breath research

authors： Högman M,Thornadtsson A,Liv P,Hua-Huy T,Dinh-Xuan AT,Tufvesson E,Dressel H,Janson C,Koskela K,Oksa P,Sauni R,Uitti J,Moilanen E,Lehtimäki L

更新日期：2017-09-13 00:00:00

abstract：:Wheeze is a common symptom in preschool children. The role of bacteria, regulatory T (T(reg)) cells and their association with airway inflammation in preschool wheeze is largely unknown. We evaluated inflammatory markers in exhaled breath condensate (EBC), bacterial colonization and circulating T(reg) cells in prescho...

journal_title：Journal of breath research

authors： van de Kant KD,Klaassen EM,van Aerde KJ,Damoiseaux J,Bruggeman CA,Stelma FF,Stobberingh EE,Muris JW,Jöbsis Q,van Schayck OC,Dompeling E

更新日期：2012-12-01 00:00:00

abstract：:The forehead was studied as a possible sampling site for capturing changes in volatile organic compound (VOC) profiles associated with psychological-stress. Skin-VOCs were sampled with a polydimethylsilicone (PDMS)-coupon and the resulting VOCs were recovered and analysed with two-stage thermal desorption gas chromato...

journal_title：Journal of breath research

authors： Martin HJ,Turner MA,Bandelow S,Edwards L,Riazanskaia S,Thomas CL

更新日期：2016-11-21 00:00:00

abstract：:Poor compliance to prescribed medication regimens in clinical trials continues to be a major obstacle to drug development success and cost reduction, and there is no gold standard technology that is cheap and effective to reliably measure drug compliance. This paper presents a new drug compliance scheme based on the d...

journal_title：Journal of breath research

authors： Meka VV,Lutz BJ,Melker RJ,Euliano NR

更新日期：2007-12-01 00:00:00

abstract：:In the current pilot study we aimed to determine whether breath analysis could be used to help recognise intra-abdominal infection, using acute appendicitis as an exemplar condition. Our study included 53 patients (aged 18-88 years) divided into three groups: appendix group, 26 (13 male) patients suffering from acute ...

journal_title：Journal of breath research

authors： Andrews BT,Das P,Denzer W,Ritchie GA,Peverall R,Hamade AM,Hancock G

更新日期：2020-10-22 00:00:00

abstract：:The measurement of the peak exhaled breath temperature (EBT) during multiple tidal breaths offers an easy, non-invasive tool for monitoring airway inflammation. Chronic obstructive pulmonary disease (COPD) is linked to airway inflammation, which is further aggravated by exacerbations of the disease. However, the peak ...

journal_title：Journal of breath research

authors： Lázár Z,Bikov A,Martinovszky F,Gálffy G,Losonczy G,Horváth I

更新日期：2014-09-18 00:00:00

abstract：:Breath tests have been used to investigate many physiological functions. Recently, we have developed a breath test system by using a non-invasive technique in conscious rats. In this study, we investigated the effect of atropine sulfate on the gastric emptying and gastrocecal transit time using [1-(13)C]acetic acid an...

journal_title：Journal of breath research

authors： Uchida M,Yoshida K,Shimizu K

更新日期：2009-12-01 00:00:00

abstract：:In the present longitudinal study, we followed volatile organic compounds (VOCs) excreted in exhaled breath of 20 healthy individuals over time, while adhering to a gluten-free diet for 4 weeks prior to adherence to a normal diet. We used gas chromatography coupled with mass spectrometry (TD-GC-tof-MS) in combination ...

journal_title：Journal of breath research

authors： Baranska A,Tigchelaar E,Smolinska A,Dallinga JW,Moonen EJ,Dekens JA,Wijmenga C,Zhernakova A,van Schooten FJ

更新日期：2013-09-01 00:00:00

abstract：:The analysis of volatile organic compounds (VOCs) by an electronic nose (e-nose) is a groundbreaking method that provides distinct exhaled molecular patterns in several respiratory and systemic diseases. It has been shown that an e-nose can detect obstructive sleep apnea (OSA) as well as chronic obstructive pulmonary ...

journal_title：Journal of breath research

authors： Dragonieri S,Quaranta VN,Carratu P,Ranieri T,Resta O

更新日期：2016-11-03 00:00:00

abstract：:The data obtained for the concentration distributions of the most abundant volatile metabolites in exhaled breath determined in two independent studies are reviewed, the first limited study involving five healthy volunteers providing daily breath samples over a month, and the subsequent study involving 30 healthy volu...

journal_title：Journal of breath research

authors： Smith D,Turner C,Spaněl P

更新日期：2007-09-01 00:00:00

abstract：:This study aimed to analyze the impact of chewing gum on halitosis parameters. Three databases were searched with the following focused question: 'Can chewing gum additionally reduce halitosis parameters, such as organoleptic scores and volatile sulfur compounds (VSC), when compared to a control treatment'? Controlled...

journal_title：Journal of breath research

authors： Muniz FW,Friedrich SA,Silveira CF,Rösing CK

更新日期：2017-02-17 00:00:00

abstract：:Bronchiectasis, bronchiolectasis, and bronchiolisation of alveolar regions are salient features of idiopathic pulmonary fibrosis (IPF). We asked whether IPF was associated with physiological changes consistent with increases in the volume of conducting airways, and whether airway volume was related to the severity of ...

journal_title：Journal of breath research

authors： Plantier L,Debray MP,Estellat C,Flamant M,Roy C,Bancal C,Borie R,Israël-Biet D,Mal H,Crestani B,Delclaux C

更新日期：2016-02-01 00:00:00

abstract：:Tongue coating (TC) mainly consists of protein mostly from exfoliated epithelial cells. Until now, to reduce TC accumulation, only mechanical measures have been available, and the procedure involves unpleasant side effects, such as gagging reflex or carcinogenesis related to mechanical stimulation. We expected that pr...

journal_title：Journal of breath research

authors： Nohno K,Yamaga T,Kaneko N,Miyazaki H

更新日期：2012-03-01 00:00:00

abstract：:The results of experiments are described in which a known quantity of sterile deuterated water is injected directly into the pulmonary circulation via the right internal jugular vein of several haemodialysis patients and the deuterium to hydrogen ratio, D/H, in the exhaled lung water was measured using the flowing aft...

journal_title：Journal of breath research

authors： Tan BK,Davies SJ,Spaněl P,Smith D

更新日期：2012-09-01 00:00:00

abstract：:Despite growing interest and considerable progress in breath research over the last decade, standardized practices for the sampling and analysis of breath gas volatiles remain elusive. The primary reasons for this are (a) the rich chemical diversity of exhaled breath that covers an extensive range of volatile organic ...

journal_title：Journal of breath research

authors： Herbig J,Beauchamp J

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous disease and airflow limitation and symptoms only partially capture such heterogeneity. Since COPD is known to affect the production of volatile organic compounds (VOCs), we aimed to verify to which extent exhaled VOCs can characterize new...

journal_title：Journal of breath research

authors： Scarlata S,Finamore P,Santangelo S,Giannunzio G,Pennazza G,Grasso S,Santonico M,Incalzi RA

更新日期：2018-06-08 00:00:00

abstract：:Oral malodour is a common condition which affects a large proportion of the population, resulting in social, emotional and psychological stress. Certain oral bacteria form a coating called a biofilm on the tongue dorsum and degrade organic compounds releasing volatile sulfur compounds that are malodourous. Current che...

journal_title：Journal of breath research

authors： Rai M,Spratt D,Gomez-Pereira PR,Patel J,Nair SP

更新日期：2016-10-18 00:00:00

abstract：:Biogenic amines are interesting compounds which may be of use for medical diagnosis or therapeutic monitoring. The present paper deals with the problems that occur with concentration determination of dimethylamine (DMA) and trimethylamine (TMA). These occur in the breath of people suffering from renal disease. The mea...

journal_title：Journal of breath research

authors： Wzorek B,Mochalski P,Sliwka I,Amann A

更新日期：2010-06-01 00:00:00

abstract：:Early detection of lung cancer (LC) is a priority since LC is characterized by symptoms mimicking other respiratory conditions, but it remains the leading cause of oncological disease death. Properly trained dogs can perceive the volatile organic compounds (VOCs) related to cancer thanks to their acute sense of smell....

journal_title：Journal of breath research

authors： Mazzola SM,Pirrone F,Sedda G,Gasparri R,Romano R,Spaggiari L,Mariangela A

更新日期：2020-03-11 00:00:00

abstract：:The human genome is the counterpart to the human exposome with respect to the gene × environment interaction that describes health state and outcome. The genome has already been sequenced and is in the process of being assessed for specific functionality; to similarly decode the exposome will require the measurement a...

journal_title：Journal of breath research

authors： Pleil JD,Stiegel MA,Sobus JR

更新日期：2011-12-01 00:00:00

abstract：:While there has been progress in making use of breath tests to guide clinical decision making, the full potential of exhaled breath analysis still remains to be exploited. Here we summarize some of the reasons why this is the case, what we have done so far to overcome some of the existing obstacles, and our vision of ...

journal_title：Journal of breath research

authors： Singh KD,Del Miguel GV,Gaugg MT,Ibañez AJ,Zenobi R,Kohler M,Frey U,Sinues PM

更新日期：2018-02-07 00:00:00

abstract：:Blood ammonia is routinely used in clinical settings to assess systemic ammonia in hepatic encephalopathy and urea cycle disorders. Despite its drawbacks, blood measurement is often used as a comparator in breath studies because it is a standard clinical test. We sought to evaluate sources of measurement error and pot...

journal_title：Journal of breath research

authors： Spacek LA,Mudalel M,Tittel F,Risby TH,Solga SF

更新日期：2015-12-14 00:00:00