Treatment of psychogenic polydipsia with acetazolamide: a report of 5 cases.

Abstract:

OBJECTIVE:Psychogenic polydipsia occurs frequently in patients with chronic psychiatric illness and is often unmanageable. We herein report 5 patients in whom acetazolamide was trialed for this symptom. METHODS:We encountered a case in which polydipsia improved with incidental administration of acetazolamide. We then used this treatment for 4 additional cases of treatment-resistant psychogenic polydipsia, some of which were accompanied by hyponatremia. RESULTS:Acetazolamide improved polydipsia and/or hyponatremia in 4 of the 5 cases. This treatment was well tolerated and allowed 3 of the patients to permanently leave isolation. CONCLUSION:Acetazolamide appears to have a beneficial effect in psychogenic polydipsia.

journal_name

Clin Neuropharmacol

authors

Takagi S,Watanabe Y,Imaoka T,Sakata M,Watanabe M

doi

10.1097/WNF.0b013e318205070b

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

5-7

issue

1

eissn

0362-5664

issn

1537-162X

pii

00002826-201101000-00002

journal_volume

34

pub_type

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