Abstract:
:Synapses, points of contact between axons and dendrites, are conduits for the flow of information in the circuitry of the central nervous system. The strength of synaptic transmission reflects the interconnectedness of the axons and dendrites at synapses; synaptic strength in turn is modified by the frequency with which the synapses are stimulated. This modulation of synaptic strength, or synaptic plasticity, probably forms the cellular basis for learning and memory. RNA metabolism, particularly translational control at or near the synapse, is one process that controls long-lasting synaptic plasticity and, by extension, memory formation and consolidation. In the present paper, I review some salient features of translational control of synaptic plasticity.
journal_name
Biochem Soc Transjournal_title
Biochemical Society transactionsauthors
Richter JDdoi
10.1042/BST0381527subject
Has Abstractpub_date
2010-12-01 00:00:00pages
1527-30issue
6eissn
0300-5127issn
1470-8752pii
BST0381527journal_volume
38pub_type
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