Abstract:
:The crucial role of ubiquitin signalling in genome-integrity maintenance was first recognized in 1987 by Stefan Jentsch and Alex Varshavsky, who showed that Rad6-the repair protein involved in DNA damage tolerance-is a ubiquitin-conjugating enzyme. Although this discovery inspired extensive research and led to the discovery of genome surveillance pathways that are fuelled by proteolytic and regulatory ubiquitylation and SUMOylation, it took more than two decades for these fields to meet at a dedicated interdisciplinary conference. This was rectified at an EMBO workshop held between 1 and 5 September on Red Island, Rovinj, Croatia.
journal_name
EMBO Repjournal_title
EMBO reportsauthors
Lukas Jdoi
10.1038/embor.2010.180subject
Has Abstractpub_date
2010-12-01 00:00:00pages
907-9issue
12eissn
1469-221Xissn
1469-3178pii
embor2010180journal_volume
11pub_type
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