Spherical bioactive glass particles and their interaction with human mesenchymal stem cells in vitro.

abstract：:Fluorapatite (FA)-collagen composites were synthesized via a biomimetic coprecipitation method in order to improve the structural stability and cellular responses. Different amounts of ammonium fluoride (NH4F), acting as a fluorine source for FA, were added to the precipitation of the composites. The precipitated comp...

journal_title：Biomaterials

authors： Yoon BH,Kim HW,Lee SH,Bae CJ,Koh YH,Kong YM,Kim HE

更新日期：2005-06-01 00:00:00

abstract：:Dextran derivatives are biosynthetic polyanionic polymers which exert some of the heparin properties such as regulating the activity of several heparin-binding growth factors. Based on a reproducible synthetic procedure, we have synthesized a new generation of dextran derivatives named dextran methylcarboxylate benzyl...

journal_title：Biomaterials

authors： Vercoutter-Edouart AS,Dubreucq G,Vanhoecke B,Rigaut C,Renaux F,Dahri-Correia L,Lemoine J,Bracke M,Michalski JC,Correia J

更新日期：2008-05-01 00:00:00

abstract：:A major role of respiratory mucus is to trap inhaled particles, including pathogens and environmental particulates, to limit body exposure. Despite the tremendous health implications, how particle size and surface chemistry affect mobility in respiratory mucus from humans without lung disease is not known. We prepared...

journal_title：Biomaterials

authors： Schuster BS,Suk JS,Woodworth GF,Hanes J

更新日期：2013-04-01 00:00:00

abstract：:A nucleus pulposus prosthesis (NPP) made of the hydrogel N-vinyl-2-pyrrolidinone copolymerized with 2-(4'-iodobenzoyl)-oxo-ethyl methacrylate has recently been developed. The special features of this NPP, i.e. intrinsic radiopacity and its ability to swell in situ to fill the nucleus cavity and restore disc height, we...

journal_title：Biomaterials

authors： Bergknut N,Smolders LA,Koole LH,Voorhout G,Hagman RE,Lagerstedt AS,Saralidze K,Hazewinkel HA,van der Veen AJ,Meij BP

更新日期：2010-09-01 00:00:00

abstract：:Inspired by nature's toughening mechanisms, we designed a new polyhedral oligomeric silsesquioxane (POSS)-derived hybrid glass (PHG) that has covalent interactions on the molecular scale between the inorganic POSS cage and organic phase. These features allow "elastic deformation" of the inorganic POSS cage in limited ...

journal_title：Biomaterials

authors： Zhou X,Sahai N,Qi L,Mankoci S,Zhao W

更新日期：2015-05-01 00:00:00

abstract：:The nanotopography and nanoscale geometry of the extra-cellular matrix (ECM) are important regulators of cell adhesion, motility and fate decision. However, unlike the sensing of matrix mechanics and ECM density, the molecular processes regulating the direct sensing of the ECM nanotopography and nanoscale geometry are...

journal_title：Biomaterials

authors： Di Cio S,Iskratsch T,Connelly JT,Gautrot JE

更新日期：2020-02-01 00:00:00

abstract：:The ultra-short pulse microwave could excite to the strong thermoacoustic (TA) shock wave and deeply penetrate in the biological tissues. Based on this, we developed a novel deep-seated tumor therapy modality with mitochondria-targeting single wall carbon nanotubes (SWNTs) as microwave absorbing agents, which act effi...

journal_title：Biomaterials

authors： Wen L,Ding W,Yang S,Xing D

更新日期：2016-01-01 00:00:00

abstract：:The conventional biomimetic apatite coating process can be accelerated by immersing substrates into concentrated simulated body fluid (5 x SBF) at 37 degrees C to form an initial coating of apatite precursor spheres, and transform the precursors into plate-like apatite structures. Depending on processing parameters, d...

journal_title：Biomaterials

authors： Chou YF,Huang W,Dunn JC,Miller TA,Wu BM

更新日期：2005-01-01 00:00:00

abstract：:The aim of the present study was to test the hypothesis that oligonucleotides can be used for anchorage and slow release of osteogenic growth factors such as BMP to enhance the osteogenic activity of a titanium implant surface. Strands of 60-mer non-coding DNA oligonucleotides (ODN) were bound to an acid-etched sandbl...

journal_title：Biomaterials

authors： Schliephake H,Bötel C,Förster A,Schwenzer B,Reichert J,Scharnweber D

更新日期：2012-02-01 00:00:00

abstract：:The water-soluble, low toxic and less biodegradable chitosan derivative N-succinyl-chitosan (Suc-chitosan) was investigated for body distribution and urinary excretion on a long-time scale (24-72 h after i.v. injection) using a fluorescein-labeling technique. Fluorescein isothiocyanate (FITC)-labeled Suc-chitosan (Suc...

journal_title：Biomaterials

authors： Kato Y,Onishi H,Machida Y

更新日期：2000-08-01 00:00:00

abstract：:Acellular porcine cornea stroma (APCS) prepared using pancreatic phospholipase A(2) was proven to be promising corneal scaffold. However, its dense ultrastructure provides insufficient space that prevents the seeded cells from organizing into a functional tissue. In this report, freezing dry APCS (FD-APCS) biomaterial...

journal_title：Biomaterials

authors： Xiao J,Duan H,Liu Z,Wu Z,Lan Y,Zhang W,Li C,Chen F,Zhou Q,Wang X,Huang J,Wang Z

更新日期：2011-10-01 00:00:00

abstract：:To achieve an optimum drug delivery such as targeting or controlled release utilizing bioconjugation with polymeric modifier, the conjugate between drugs and polymeric modifiers must be designed to show desirable pharmacokinetic characteristics in vivo. In this study, we assessed the biopharmaceutical properties of va...

journal_title：Biomaterials

authors： Kaneda Y,Tsutsumi Y,Yoshioka Y,Kamada H,Yamamoto Y,Kodaira H,Tsunoda S,Okamoto T,Mukai Y,Shibata H,Nakagawa S,Mayumi T

更新日期：2004-07-01 00:00:00

abstract：:Myotube formation is crucial to restoring muscular functions, and biomaterials that enhance the myoblast differentiation into myotubes are highly desirable for muscular repair. Here, we report the synthesis of electroactive, ductile, and degradable copolymers and their application in enhancing the differentiation of m...

journal_title：Biomaterials

authors： Xie M,Wang L,Guo B,Wang Z,Chen YE,Ma PX

更新日期：2015-12-01 00:00:00

abstract：:The use of defined in vitro systems to study the developmental and physiological characteristics of a variety of cell types is increasing, due in large part to their ease of integration with tissue engineering, regenerative medicine, and high-throughput screening applications. In this study, myotubes derived from feta...

journal_title：Biomaterials

authors： Das M,Rumsey JW,Bhargava N,Stancescu M,Hickman JJ

更新日期：2009-10-01 00:00:00

abstract：:Carbon fiber implants were used to fill osteochondral defects created on the articular surface of the patella of 36 rabbits, for the purpose of studying the long-term histological changes of the repair process. Six months after surgery the defect was filled by fibrous tissue, where the superficial area was organized p...

journal_title：Biomaterials

authors： Carranza-Bencano A,Armas-Padrón JR,Gili-Miner M,Lozano MA

更新日期：2000-11-01 00:00:00

abstract：:Polydimethacrylate resins were prepared by photopolymerization of Bis-GMA, TEGDMA, UDMA or Bis-EMA (4) monomer, initiated by camphoroquinone/N,N-dimethylaminoethyl methacrylate system. The study of physical properties of these resins showed that TEGDMA seems to create the most dense polymer network, which however is t...

journal_title：Biomaterials

authors： Sideridou I,Tserki V,Papanastasiou G

更新日期：2003-02-01 00:00:00

abstract：:The management of trauma-associated nerve defects is difficult because of the absence of autologous donor motor or sensory nerves. Pre-clinical development and clinical experience has shown that damaged nerves can be surgically repaired using a tubular conduit interposed across the defect. Acceptable patient outcomes ...

journal_title：Biomaterials

authors： Sierpinski P,Garrett J,Ma J,Apel P,Klorig D,Smith T,Koman LA,Atala A,Van Dyke M

更新日期：2008-01-01 00:00:00

abstract：:This work exploits the thermal responsive phase behavior of hydroxypropylcellulose to produce 3D interconnected macroporous hydrogels in aqueous environment. Hydroxypropylcellulose was modified with allyl isocyanate, and their temperature mediated phase behavior was studied as a function of degree of modification (DS)...

journal_title：Biomaterials

authors： Yue Z,Wen F,Gao S,Ang MY,Pallathadka PK,Liu L,Yu H

更新日期：2010-11-01 00:00:00

abstract：:It is known that the organic molecules can provide an effective means to manipulate the surface properties of the biodegradable ceramic. There are two ways to modify the surface of the biodegradable ceramic by organic molecules. The first one is through surface adsorption but organic molecules will easily be washed ou...

journal_title：Biomaterials

authors： Dong GC,Sun JS,Yao CH,Jiang GJ,Huang CW,Lin FH

更新日期：2001-12-01 00:00:00

abstract：:Achieving and maintaining safe and reliable lineage specific differentiation of stem cells is important for clinical translation of tissue engineering strategies. In an effort to circumvent the multitude of problems arising from the usage of growth factors and growth factor delivery systems, we have explored the use o...

journal_title：Biomaterials

authors： Huang CC,Narayanan R,Alapati S,Ravindran S

更新日期：2016-12-01 00:00:00

abstract：:High throughput cellular studies require small sample volume to reduce costs and enhance sensitivity. Microfluidics-generated water-in-oil (W/O) single emulsion droplet systems, in particular, provide uniform, well defined and discrete microenvironment for cell culture, screening, and sorting. However, these single em...

journal_title：Biomaterials

authors： Zhang Y,Ho YP,Chiu YL,Chan HF,Chlebina B,Schuhmann T,You L,Leong KW

更新日期：2013-06-01 00:00:00

abstract：:Nickel-titanium shape-memory alloys (NiTi-SMA) were coated with calcium phosphate by dipping in oversaturated calcium phosphate solution. The layer thickness (typically 5-20 micrometer) can be varied by choice of the immersion time. The porous nature of the layer of microcrystals makes it mechanically stable enough to...

journal_title：Biomaterials

authors： Choi J,Bogdanski D,Köller M,Esenwein SA,Müller D,Muhr G,Epple M

更新日期：2003-09-01 00:00:00

abstract：:The nanopore size and roughness of nanoporous surface are two critical variables in determining stem cell fate, but little is known about the contribution from each cue individually. To address this gap, we use two-dimensional nanoporous membranes with controlled nanopore size and roughness to culture bone marrow-deri...

journal_title：Biomaterials

authors： Xia J,Yuan Y,Wu H,Huang Y,Weitz DA

更新日期：2020-07-01 00:00:00

abstract：:Studies have suggested that mesenchymal stem cells (MSCs) have therapeutic effects following traumatic brain injury (TBI). However, cell distribution and survival rate are two major barriers to their success as therapeutic treatment. The improvement of cell therapy using collagen delivery matrices had been reported. H...

journal_title：Biomaterials

authors： Guan J,Zhu Z,Zhao RC,Xiao Z,Wu C,Han Q,Chen L,Tong W,Zhang J,Han Q,Gao J,Feng M,Bao X,Dai J,Wang R

更新日期：2013-08-01 00:00:00

abstract：:Three-dimensional (3D) culture of hepatocytes leads to improved and prolonged synthetic and metabolic functions, but the underlying molecular mechanisms are unknown. In order to investigate the role of 3D cell-cell interactions in maintaining hepatocyte differentiated functions ex vivo, primary mouse hepatocytes were ...

journal_title：Biomaterials

authors： Chang TT,Hughes-Fulford M

更新日期：2014-02-01 00:00:00

abstract：:The early biological response at titanium (Ti), copper (Cu)-coated Ti and sham sites was evaluated in an in vivo rat model. Material surface chemical and topographical properties were characterized using Auger electron spectroscopy, energy dispersive X-ray spectroscopy and interferometry, respectively. The number of l...

journal_title：Biomaterials

authors： Suska F,Gretzer C,Esposito M,Emanuelsson L,Wennerberg A,Tengvall P,Thomsen P

更新日期：2005-02-01 00:00:00

abstract：:The effects of phosphorylated chitin (P-chitin) on the tissue responses to two kinds of calcium phosphate cements (CPCs) were investigated using experimental rabbits. One of them consisting of monocalcium phosphate monohydrate, calcium oxide, 1 M phosphate buffer (pH: 7.4) and different amounts of P-chitin (CPC-I or P...

journal_title：Biomaterials

authors： Wang X,Ma J,Feng Q,Cui F

更新日期：2002-12-01 00:00:00

abstract：:Skeletal muscle is a highly organized tissue in which the extracellular matrix (ECM) is composed of highly-aligned cables of collagen with nanoscale feature sizes, and provides structural and functional support to muscle fibers. As such, the transplantation of disorganized tissues or the direct injection of cells into...

journal_title：Biomaterials

authors： Yang HS,Ieronimakis N,Tsui JH,Kim HN,Suh KY,Reyes M,Kim DH

更新日期：2014-02-01 00:00:00

abstract：:In order to assess the suitability of polymer tissue scaffolds for use in regenerative medicine, methods to characterise scaffolds are needed. This requires the scaffold's structure to be determined for which X-ray microscopic computed tomography (X-ray micro CT) is widely used. However, because scaffolds are generall...

journal_title：Biomaterials

authors： Morris DE,Mather ML,Crowe JA

更新日期：2009-09-01 00:00:00

abstract：:Despite serving as the clinical "gold standard" treatment for critical size bone defects, decellularized allografts suffer from long-term failure rates of ~60% due to the absence of the periosteum. Stem and osteoprogenitor cells within the periosteum orchestrate autograft healing through host cell recruitment, which i...

journal_title：Biomaterials

authors： Li Y,Hoffman MD,Benoit DSW

更新日期：2021-01-01 00:00:00