Optic pathway glioma: long-term visual outcome in children without neurofibromatosis type-1.

abstract：BACKGROUND:Extracranial malignant rhabdoid tumor (MRT) is a rare pediatric cancer with a poor prognosis. The kidney is the most common site. Isolated reports have shown improvements in patient survival, but no specific treatment regimen has shown efficacy over others. PROCEDURE:Retrospective review of patients diagnos...

journal_title：Pediatric blood & cancer

authors： Venkatramani R,Shoureshi P,Malvar J,Zhou S,Mascarenhas L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Ewing sarcoma (ES), a highly aggressive tumor of children and young adults, is characterized most commonly by an 11;22 chromosomal translocation that fuses EWSR1 located at 22q12 with FLI1, coding for a member of the ETS family of transcription factors. Although genetic changes in ES have been extensively re...

journal_title：Pediatric blood & cancer

authors： Nestheide S,Bridge JA,Barnes M,Frayer R,Sumegi J

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:MOPP (mechlorethamine, vincristine, procarbazine, prednisone) and ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) are effective therapies for Hodgkin disease (HD) that may cause long-term toxicities in children. APE (cytosine arabinoside, cisplatin, etoposide) is a non-cross-resistant regimen wit...

journal_title：Pediatric blood & cancer

authors： Wimmer RS,Chauvenet AR,London WB,Villaluna D,de Alarcon PA,Schwartz CL

更新日期：2006-03-01 00:00:00

abstract：:The global burden of sickle cell disease (SCD) is now being increasingly realized. SCD poses a significant public health problem in sub-Saharan Africa, the Middle East, some regions of India, the Caribbean, and Brazil. In many of these regions, progress in the management of SCD has been slow. Long-term North-South and...

journal_title：Pediatric blood & cancer

authors： Aygun B,Odame I

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Osteopathy is one of the common initial symptoms of acute lymphocytic leukemia (ALL) in children and adolescents, but multiple osteolysis accompanied by hypercalcemia is rarely observed. PROCEDURE:We treated a 14-year-old female who had multiple osteolytic lesions and hypercalcemia at initial onset of ALL. ...

journal_title：Pediatric blood & cancer

authors： Shimonodan H,Nagayama J,Nagatoshi Y,Hatanaka M,Takada A,Iguchi H,Oda Y,Okamura J

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Dexamethasone is more efficacious than prednisone in the treatment of acute lymphoblastic leukemia (ALL), but has also been associated with greater toxicity. We compared neuropsychological outcomes for patients treated on DFCI ALL Consortium Protocol 00-01, which included a randomized comparison of the two s...

journal_title：Pediatric blood & cancer

authors： Waber DP,McCabe M,Sebree M,Forbes PW,Adams H,Alyman C,Sands SA,Robaey P,Romero I,Routhier MÈ,Girard JM,Sallan SE,Silverman LB

更新日期：2013-11-01 00:00:00

abstract：:Adolescents and young adults (AYA) with acute lymphoblastic leukaemia (ALL) constitute a distinct population from children and older adults. Based on patterns of referral, they may be treated by either paediatric or adult oncologists. As a group, AYA with ALL have a worse survival and event-free survival (EFS) compare...

journal_title：Pediatric blood & cancer

authors： Ramanujachar R,Richards S,Hann I,Webb D

更新日期：2006-11-01 00:00:00

abstract：:The Children's Oncology Group (COG) is a multi-institutional cooperative group dedicated to childhood cancer research that has helped to increase the survival of children with cancer through clinical trials. These clinical trials include a standardized regimen of imaging examinations performed prior to, during, and fo...

journal_title：Pediatric blood & cancer

authors： Meyer JS,Nadel HR,Marina N,Womer RB,Brown KL,Eary JF,Gorlick R,Grier HE,Randall RL,Lawlor ER,Lessnick SL,Schomberg PJ,Kailo MD

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To evaluate and compare psychological distress in long-term survivors of solid tumors diagnosed in childhood and their siblings, and to identify significant correlates of psychological distress. PROCEDURE:Adult survivors (2,778) of solid tumors diagnosed in childhood and 2,925 siblings completed a long-term fo...

journal_title：Pediatric blood & cancer

authors： Zebrack BJ,Zevon MA,Turk N,Nagarajan R,Whitton J,Robison LL,Zeltzer LK

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Better predictors of outcome would allow improved risk-adapted therapy for pediatric nonmetastatic osteosarcoma of the extremity. We investigated the predictive value of MR imaging-based measures of absolute and relative tumor size and volume at the time of diagnosis. We also assessed the relation of tumor s...

journal_title：Pediatric blood & cancer

authors： Kaste SC,Liu T,Billups CA,Daw NC,Pratt CB,Meyer WH

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Children with cancer experience a wide range of conditions that require urgent evaluation in the emergency department (ED), yet variation in admission rates is poorly documented. PROCEDURE:We performed a retrospective cohort study using the Pediatric Health Information System of ED encounters by children wi...

journal_title：Pediatric blood & cancer

authors： Mueller EL,Jacob SA,Cochrane AR,Carroll AE,Bennett WE Jr

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Fever in severe chemotherapy-induced neutropenia (FN) is the most frequent manifestation of a potentially lethal complication of current intensive chemotherapy regimens. This study aimed at establishing models predicting the risk of FN, and of FN with bacteremia, in pediatric cancer patients. METHODS:In a s...

journal_title：Pediatric blood & cancer

authors： Wicki S,Keisker A,Aebi C,Leibundgut K,Hirt A,Ammann RA

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Cisplatin (CDDP) ototoxicity is a significant side effect of the current treatment of medulloblastoma (MB). Cumulative dose of CDDP and age are recognized risk factors for hearing loss, but inter-individual susceptibility limits our ability to identify patients at risk for hearing loss. We describe the kinet...

journal_title：Pediatric blood & cancer

authors： Lafay-Cousin L,Purdy E,Huang A,Cushing SL,Papaioannou V,Nettel-Aguirre A,Bouffet E

更新日期：2013-02-01 00:00:00

abstract：:Inherited bone marrow failure syndromes (IBMFS) are rare cancer predisposition syndromes with an especially high risk of transformation to myelodysplastic syndrome (MDS) and/or acute myeloid leukemia (AML). We performed a retrospective systematic review of reported MDS/AML arising in the eight most common IBMFS to det...

journal_title：Pediatric blood & cancer

authors： Pezeshki A,Podder S,Kamel R,Corey SJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The treatment of central nervous system (CNS) germ cell tumors (GCT) remains controversial. The purpose of this study was to demonstrate efficacy of a chemotherapy only strategy, with less morbidity, when compared to regimens with irradiation. METHODS:Between January 2001 and December 2004 newly diagnosed p...

journal_title：Pediatric blood & cancer

authors： da Silva NS,Cappellano AM,Diez B,Cavalheiro S,Gardner S,Wisoff J,Kellie S,Parker R,Garvin J,Finlay J

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Patient transition readiness self-assessment tools and investigation into patient and parent perceptions of the transition process from pediatric to adult care models have informed recognition of gaps in care, particularly for those with chronic disease. Implementation of a longitudinal transition process wi...

journal_title：Pediatric blood & cancer

authors： Croteau SE,Padula M,Quint K,D'Angelo L,Neufeld EJ

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:Major advances in the field of pediatric oncology have resulted from rigorous, prospective clinical oncology research trials. Optimizing access for all children and adolescents to clinical research trials is an important goal. Barriers to clinical trial enrollment are numerous, involving the health care sy...

journal_title：Pediatric blood & cancer

authors： Russo C,Stout L,House T,Santana VM

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Although respiratory syncytial virus (RSV) is the leading cause of pediatric lower respiratory tract infections, the burden of RSV in children with sickle cell disease (SCD) is unknown. METHODS:We conducted a retrospective, nested, case-control study of children with SCD <18 years who had respiratory viral ...

journal_title：Pediatric blood & cancer

authors： Rostad CA,Maillis AN,Lai K,Bakshi N,Jerris RC,Lane PA,Yee ME,Yildirim I

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Premature newborns are vulnerable to iron imbalance, although the iron homeostasis during the perinatal period remains unclear. To clarify the iron metabolism of premature infants, we measured serum prohepcidin concentrations of preterm infants, and analyzed the association with iron parameters. METHODS:Sev...

journal_title：Pediatric blood & cancer

authors： Kitajima J,Ohga S,Kinjo T,Ochiai M,Takahata Y,Honjo S,Hara T

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Children with acute lymphoblastic leukemia (ALL) who fail to achieve complete remission (CR) after induction therapy (induction failure: IF) have a poor prognosis; however, there have been few prospective studies in patients with IF. PATIENTS AND METHODS:Between April 1997 and March 2005, 27 of 1,237 leukem...

journal_title：Pediatric blood & cancer

authors： Suzuki N,Yumura-Yagi K,Yoshida M,Hara J,Nishimura S,Kudoh T,Tawa A,Usami I,Tanizawa A,Hori H,Ito Y,Miyaji R,Oda M,Kato K,Hamamoto K,Osugi Y,Hashii Y,Nakahata T,Horibe K,Japan Association of Childhood Leukemia Study

更新日期：2010-01-01 00:00:00

abstract：:Severe congenital neutropenia (SCN) is a bone marrow failure disease with an autosomal dominant inheritance from mutations in ELANE. Here, we report a 7-week-old Korean male with SCN. His elder sister died from pneumonia at 2 years. Direct sequencing of ELANE in the proband identified a heterozygous novel frameshift m...

journal_title：Pediatric blood & cancer

authors： Kim HJ,Song MJ,Lee KO,Kim SH,Kim HJ

更新日期：2015-12-01 00:00:00

abstract：:Pediatric cancer survivors have increased risk of obesity, hypertension, dyslipidemia, and type 2 diabetes, leading to premature cardiovascular disease (CVD). Multiple tissues that are involved in glucose homeostasis and lipid metabolism are adversely affected by chemotherapy. This review highlights the relevant tissu...

journal_title：Pediatric blood & cancer

authors： Rosen GP,Nguyen HT,Shaibi GQ

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Posterior fossa syndrome (PFS) is defined as the temporary and complete loss of speech after posterior fossa surgery. The goal of this study was to identify incidence and risk factors for PFS and to determine accompanying neurobehavioral and psychologic problems. PROCEDURE:Between May 2007 and April 2009, c...

journal_title：Pediatric blood & cancer

authors： Küpeli S,Yalçın B,Bilginer B,Akalan N,Haksal P,Büyükpamukçu M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Although "aspirin resistance" (AR-inadequate platelet inhibition as suggested by in vitro testing of aspirin-treated patients) has been widely studied in adults and linked to increased risk of adverse outcomes, its prevalence and clinical significance are largely unknown in children. PROCEDURE:To determine ...

journal_title：Pediatric blood & cancer

authors： Yee DL,Dinu BR,Sun CW,Edwards RM,Justino H,Teruya J,Bray PF,Bomgaars L

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Current guidelines recommend high-priority treatment of severe sickle cell disease (SCD) pain with opioids; however, patients with SCD have historically been undertreated. We used mixed methods to assess pediatric residents' perceptions toward opioid use in SCD pain management. METHODS:We distributed a surve...

journal_title：Pediatric blood & cancer

authors： Fearon A,Marsh A,Kim J,Treadwell M

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Childhood germ cell tumors (cGCTs), believed to arise from transformed primordial germ cells by an unknown mechanism, provide a unique model system for investigating cell signaling, pluripotency, and the microenvironment of neoplastic stem cells (NSCs) in vivo. This is the first report of proteomics of cGCTs...

journal_title：Pediatric blood & cancer

authors： Haskins WE,Eedala S,Jadhav YL,Labhan MS,Pericherla VC,Perlman EJ

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To report the final analysis of survival outcomes for children with newly diagnosed high-grade glioma (HGG) treated on the "Head Start" (HS) II and III protocols with chemotherapy and intent to avoid irradiation in children <6 years old. PATIENTS AND METHODS:Between 1997 and 2009, 32 eligible children were enr...

journal_title：Pediatric blood & cancer

authors： Espinoza JC,Haley K,Patel N,Dhall G,Gardner S,Allen J,Torkildson J,Cornelius A,Rassekh R,Bedros A,Etzl M,Garvin J,Pradhan K,Corbett R,Sullivan M,McGowage G,Stein D,Jasty R,Sands SA,Ji L,Sposto R,Finlay JL

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the Pediatric Preclinical Testing Program (PPTP). PROCEDURES:Ispinesib was tes...

journal_title：Pediatric blood & cancer

authors： Carol H,Lock R,Houghton PJ,Morton CL,Kolb EA,Gorlick R,Reynolds CP,Maris JM,Keir ST,Billups CA,Smith MA

更新日期：2009-12-15 00:00:00

abstract：:Childhood, adolescent, and young adult (CAYA) cancer survivors may be at risk for a severe course of COVID-19. Little is known about the clinical course of COVID-19 in CAYA cancer survivors, or if additional preventive measures are warranted. We established a working group within the International Late Effects of Chil...

journal_title：Pediatric blood & cancer

authors： Verbruggen LC,Wang Y,Armenian SH,Ehrhardt MJ,van der Pal HJH,van Dalen EC,van As JW,Bardi E,Baust K,Berger C,Castagnola E,Devine KA,Gebauer J,Marchak JG,Glaser AW,Groll AH,Haeusler GM,den Hartogh J,Haupt R,Hjorth L

更新日期：2020-12-01 00:00:00

abstract：:A diverse panel of pediatric cancer advocates and experts, whose collective experience spans the continuum of international academic medicine, industry, government research, and cancer advocacy, recently discussed challenges for pediatric cancer research in the context of coronavirus disease 2019 (COVID-19). Specifica...

journal_title：Pediatric blood & cancer

authors： Auletta JJ,Adamson PC,Agin JE,Kearns P,Kennedy S,Kieran MW,Ludwinski DM,Knox LJ,McKay K,Rhiner P,Thiele CJ,Cripe TP

更新日期：2020-09-01 00:00:00