Construction of an integrated genetic linkage map for the A genome of Brassica napus using SSR markers derived from sequenced BACs in B. rapa.

abstract：BACKGROUND:The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines to be interrogated at genome-wide scale. However, multiple issues, such as off-target effects or low efficacies in knocking down ce...

journal_title：BMC genomics

authors： Wang L,Tu Z,Sun F

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:RNA-seq has shown huge potential for phylogenomic inferences in non-model organisms. However, error, incompleteness, and redundant assembled transcripts for each gene in de novo assembly of short reads cause noise in analyses and a large amount of missing data in the aligned matrix. To address these problems...

journal_title：BMC genomics

authors： Yang Y,Smith SA

更新日期：2013-05-14 00:00:00

abstract：BACKGROUND:Chinese bayberry (Myrica rubra Sieb. and Zucc.) is an important subtropical fruit crop and an ideal species for fruit quality research due to the rapid and substantial changes that occur during development and ripening, including changes in fruit color and taste. However, research at the molecular level is l...

journal_title：BMC genomics

authors： Feng C,Chen M,Xu CJ,Bai L,Yin XR,Li X,Allan AC,Ferguson IB,Chen KS

更新日期：2012-01-13 00:00:00

abstract：BACKGROUND:An efficient signal transduction system allows a bacterium to sense environmental cues and then to respond positively or negatively to those signals; this process is referred to as taxis. In addition to external cues, the internal metabolic state of any bacterium plays a major role in determining its ability...

journal_title：BMC genomics

authors： Sharma G,Parales R,Singer M

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Shotgun sequencing of environmental DNA is an essential technique for characterizing uncultivated microbes in situ. However, the taxonomic and functional assignment of the obtained sequence fragments remains a pressing problem. RESULTS:Existing algorithms are largely optimized for speed and coverage; in con...

journal_title：BMC genomics

authors： Stark M,Berger SA,Stamatakis A,von Mering C

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:Osteoporosis is a common and debilitating bone disease that is characterised by a low bone mineral density (BMD), a highly heritable trait. Genome-wide association studies (GWAS) have proven to be very successful in identifying common genetic variants associated with BMD adjusted for age, gender and weight, ...

journal_title：BMC genomics

authors： Mullin BH,Walsh JP,Zheng HF,Brown SJ,Surdulescu GL,Curtis C,Breen G,Dudbridge F,Richards JB,Spector TD,Wilson SG

更新日期：2016-02-25 00:00:00

abstract：BACKGROUND:To date several studies have sought to catalog the full suite of antibodies that humans naturally produce against single antigens or other specificities (repertoire). Here we analyze the properties of all sequenced repertoires in order to better understand the specificity of antibody responses. Specifically,...

journal_title：BMC genomics

authors： Arnaout RA

更新日期：2005-10-28 00:00:00

abstract：BACKGROUND:As economically relevant traits, feeding behavior and food preference domestication determine production cost and profitability. Although there are intensive research efforts on feeding behavior and food intake, little is known about food preference. Mandarin fish accept only live prey fish and refuse dead p...

journal_title：BMC genomics

authors： He S,Liang XF,Sun J,Li L,Yu Y,Huang W,Qu CM,Cao L,Bai XL,Tao YX

更新日期：2013-09-05 00:00:00

abstract：BACKGROUND:Obesity, the excessive accumulation of body fat, is a highly heritable and genetically heterogeneous disorder. The complex, polygenic basis for the disease consisting of a network of different gene variants is still not completely known. RESULTS:In the current study we generated a BAC library of the obese-p...

journal_title：BMC genomics

authors： Vogel H,Jähnert M,Stadion M,Matzke D,Scherneck S,Schürmann A

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Reliable indicators for the onset of flowering are not available for most perennial monocarpic species, representing a drawback for crops such as bamboo, agave and banana. The ability to predict and control the transition to the reproductive stage in A. tequilana would represent an advantage for field manage...

journal_title：BMC genomics

authors： Avila de Dios E,Delaye L,Simpson J

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:Carrot (Daucus carota) is a major food crop in the US and worldwide. Its capacity for storage and its lifecycle as a biennial make it an attractive species for the introduction of foreign genes, especially for oral delivery of vaccines and other therapeutic proteins. Until recently efforts to express recombi...

journal_title：BMC genomics

authors： Ruhlman T,Lee SB,Jansen RK,Hostetler JB,Tallon LJ,Town CD,Daniell H

更新日期：2006-08-31 00:00:00

abstract：BACKGROUND:Infectious laryngotracheitis virus (ILTV; gallid herpesvirus 1) infection causes high mortality and huge economic losses in the poultry industry. To protect chickens against ILTV infection, chicken-embryo origin (CEO) and tissue-culture origin (TCO) vaccines have been used. However, the transmission of vacci...

journal_title：BMC genomics

authors： Lee J,Bottje WG,Kong BW

更新日期：2012-04-24 00:00:00

abstract：BACKGROUND:Endogenous small interfering (esi)RNAs repress mRNA levels and retrotransposon mobility in Drosophila somatic cells by poorly understood mechanisms. 21 nucleotide esiRNAs are primarily generated from retrotransposons and two inverted repeat (hairpin) loci in Drosophila culture cells in a Dicer2 dependent man...

journal_title：BMC genomics

authors： Harrington AW,McKain MR,Michalski D,Bauer KM,Daugherty JM,Steiniger M

更新日期：2017-04-17 00:00:00

abstract：BACKGROUND:Cytoplasmic male sterility (CMS) is an inability to produce functional pollen that is caused by mutation of the mitochondrial genome. Comparative analyses of mitochondrial genomes of lines with and without CMS in several species have revealed structural differences between genomes, including extensive rearra...

journal_title：BMC genomics

authors： Jo YD,Choi Y,Kim DH,Kim BD,Kang BC

更新日期：2014-07-04 00:00:00

abstract：BACKGROUND:Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study, we aim to explore the phenotypic changes and possible mechanisms of C. albicans after exposure to spaceflight conditions. RESU...

journal_title：BMC genomics

authors： Wang J,Liu Y,Zhao G,Gao J,Liu J,Wu X,Xu C,Li Y

更新日期：2020-01-17 00:00:00

abstract：BACKGROUND:Proliferation and tumor differentiation captured by the genomic grade index (GGI) are important prognostic indicators in breast cancer (BC) especially for the estrogen receptor positive (ER+) disease. The aims of this study were to convert this microarray index to a qRT-PCR assay (PCR-GGI), which could be re...

journal_title：BMC genomics

authors： Toussaint J,Sieuwerts AM,Haibe-Kains B,Desmedt C,Rouas G,Harris AL,Larsimont D,Piccart M,Foekens JA,Durbecq V,Sotiriou C

更新日期：2009-09-10 00:00:00

abstract：BACKGROUND:Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene, MCOLN1, has been identified as a new member of the transient receptor potential (TRP) cation channel superfamily. Here we report the c...

journal_title：BMC genomics

authors： Falardeau JL,Kennedy JC,Acierno JS Jr,Sun M,Stahl S,Goldin E,Slaugenhaupt SA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that human populations have experienced a complex demographic history, including a recent epoch of rapid population growth that led to an excess in the proportion of rare genetic variants in humans today. This excess can impact the burden of private mutations for each individual, de...

journal_title：BMC genomics

authors： Gao F,Keinan A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either 18 or 22 homologues. The present analysis attempted to revise and ...

journal_title：BMC genomics

authors： Premzl M

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND:Homeobox-containing genes encode crucial transcription factors involved in animal, plant and fungal development, and changes to homeobox genes have been linked to the evolution of novel body plans and morphologies. In animals, some homeobox genes are clustered together in the genome, either as remnants from ...

journal_title：BMC genomics

authors： Li Y,Nong W,Baril T,Yip HY,Swale T,Hayward A,Ferrier DEK,Hui JHL

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:The Polima (pol) system of cytoplasmic male sterility (CMS) and its fertility restoration gene Rfp have been used in hybrid breeding in Brassica napus, which has greatly improved the yield of rapeseed. However, the mechanism of the male sterility transition in pol CMS remains to be determined. RESULTS:To in...

journal_title：BMC genomics

authors： An H,Yang Z,Yi B,Wen J,Shen J,Tu J,Ma C,Fu T

更新日期：2014-04-03 00:00:00

abstract：BACKGROUND:Bacillus pumilus is a Gram-positive and endospore-forming bacterium broadly existing in a variety of environmental niches. Because it produces and secrets many industrially useful enzymes, a lot of studies have been done to understand the underlying mechanisms. Among them, scoC was originally identified as a...

journal_title：BMC genomics

authors： Han LL,Liu YC,Miao CC,Feng H

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND:Iron homeostasis is a key metabolism for most organisms. In many bacterial species, coordinate regulation of iron homeostasis depends on the protein product of a Fur gene. Fur also plays roles in virulence, acid tolerance, redox-stress responses, flagella chemotaxis and metabolic pathways. RESULTS:We conduc...

journal_title：BMC genomics

authors： Yang Y,Harris DP,Luo F,Wu L,Parsons AB,Palumbo AV,Zhou J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:gammadelta T cells differ from alphabeta T cells with regard to the types of antigen with which their T cell receptors interact; gammadelta T cell antigens are not necessarily peptides nor are they presented on MHC. Cattle are considered a "gammadelta T cell high" species indicating they have an increased pr...

journal_title：BMC genomics

authors： Herzig CT,Lefranc MP,Baldwin CL

更新日期：2010-02-09 00:00:00

abstract：BACKGROUND:Interactions between fish and pathogens, that may be harmless under natural conditions, often result in serious diseases in aquaculture systems. This is especially important due to the fact that the strains used in aquaculture are derived from wild strains that may not have had enough time to adapt to new di...

journal_title：BMC genomics

authors： Rodríguez-Ramilo ST,Toro MA,Bouza C,Hermida M,Pardo BG,Cabaleiro S,Martínez P,Fernández J

更新日期：2011-11-02 00:00:00

abstract：BACKGROUND:Natural contamination and anthropogenic pollution of soils are likely to be major determinants of functioning and survival of keystone invertebrate taxa. Soil animals will have both evolutionary adaptation and genetically programmed responses to these toxic chemicals, but mechanistic understanding of such is...

journal_title：BMC genomics

authors： Owen J,Hedley BA,Svendsen C,Wren J,Jonker MJ,Hankard PK,Lister LJ,Stürzenbaum SR,Morgan AJ,Spurgeon DJ,Blaxter ML,Kille P

更新日期：2008-06-03 00:00:00

abstract：BACKGROUND:Characterizing large genomic variants is essential to expanding the research and clinical applications of genome sequencing. While multiple data types and methods are available to detect these structural variants (SVs), they remain less characterized than smaller variants because of SV diversity, complexity,...

journal_title：BMC genomics

authors： English AC,Salerno WJ,Hampton OA,Gonzaga-Jauregui C,Ambreth S,Ritter DI,Beck CR,Davis CF,Dahdouli M,Ma S,Carroll A,Veeraraghavan N,Bruestle J,Drees B,Hastie A,Lam ET,White S,Mishra P,Wang M,Han Y,Zhang F,Stankie

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:Dinoflagellates are unicellular marine and freshwater eukaryotes. They possess large nuclear genomes (1.5-245 gigabases) and produce structurally unique and biologically active polyketide secondary metabolites. Although polyketide biosynthesis is well studied in terrestrial and freshwater organisms, only rec...

journal_title：BMC genomics

authors： Beedessee G,Hisata K,Roy MC,Satoh N,Shoguchi E

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:In recent years, the number of human infections caused by opportunistic pathogens has increased dramatically. Plant rhizospheres are one of the most typical natural reservoirs for these pathogens but they also represent a great source for beneficial microbes with potential for biotechnological applications. ...

journal_title：BMC genomics

authors： Alavi P,Starcher MR,Thallinger GG,Zachow C,Müller H,Berg G

更新日期：2014-06-18 00:00:00

abstract：BACKGROUND:Drought is a lifestyle disease. Plant metabolomics has been exercised for understanding the fine-tuning of the potential pathways to surmount the adverse effects of drought stress. A broad spectrum of morphological and metabolic responses from seven Triticeae species including wild types with different droug...

journal_title：BMC genomics

authors： Ullah N,Yüce M,Neslihan Öztürk Gökçe Z,Budak H

更新日期：2017-12-15 00:00:00