Abstract:
BACKGROUND:Whether written feedback on drug prescribing in general practice affects prescribing habits is controversial. Most short-term studies showed no effect. However, the issue has not been tested in long-term studies involving the local general practitioner community. AIMS OF THE STUDY:To assess whether prescribing levels in general practice are affected by long-term, unsolicited, systematically repeated, mailed feedback. METHODS:Each of the 94 general practices in Storstrøm County, Denmark, received semi-annual, mailed feedback about their prescribing volumes and costs within 13 major drug groups, in relation to the levels for all the other 93 practices over a 7-year period in a project initiated by the local general practitioner association. Data on the number of defined daily doses (DDDs) prescribed per 1000 listed patients in each practice per 6-months, and practice characteristics, were obtained from the Pharmaceutical Database at the County Health Department. RESULTS:There was a large variation in drug prescribing volume between practices, but little within-practice variation over time. After adjustments for the influence of practice size and other potential outcome-affecting variables, there was no evidence of a general change of prescribing volume over time, no change among practices with a high or a low prescribing level, and no significant change within the various drug groups. CONCLUSIONS:We found no significant effects on prescribing levels of mailed feedback, even when repeated semi-annually during 7 years and initiated by the local general practitioner community.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Vægter K,Wahlström R,Wedel H,Svärdsudd Kdoi
10.3109/03009734.2010.487165subject
Has Abstractpub_date
2010-11-01 00:00:00pages
238-44issue
4eissn
0300-9734issn
2000-1967journal_volume
115pub_type
杂志文章abstract:OBJECTIVES:The incidence of fentanyl-induced cough (FIC) during induction of general anesthesia varies around 40% and is undesirable. It increases intracranial, intraocular, and intra-abdominal pressures. This prospective, randomized, double-blind, placebo-controlled study evaluated the effect of dexmedetomidine (DEX) ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,随机对照试验
doi:10.3109/03009734.2011.629749
更新日期:2012-03-01 00:00:00
abstract::Rats were starved for 7 days or fed a protein-free or a 25% casein diet for 7 or 14 days. Free and total ribosomes were prepared from the liver. A determination of the ratio of mg RNA of ribosomes to mg DNA of the total homogenate was made. In starved rats, RNA of free and membrane-bound ribosomes decreased to the sam...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179168
更新日期:1980-01-01 00:00:00
abstract::Abstract Pyogenic spondylitis is a common infectious disease caused by various microorganisms. It is difficult to predict the infecting microorganism at the time of initiation of treatment. Pneumonia is generally clarified into community or hospital-acquired types based on where the infection was acquired, and the i...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.687406
更新日期:2012-11-01 00:00:00
abstract::Two female patients, 63 and 78 years of age, underwent femoropopliteal bypass with polytetrafluoroethylene (PTFE) graft and distal vein cuff. They developed graft occlusion due to false aneurysm at the site of vein cuff during one and eight weeks after surgery, respectively. Improper suture technique or weak vein wall...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-178
更新日期:2000-01-01 00:00:00
abstract::Familial aggregation of patients with ovarian carcinoma is unusual. A family with four affected members in three consecutive generations is described. The tumors were all of the serous papillary adenocarcinoma type. The pattern of appearance of the malignant disorder in the present family may be explained as the resul...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179047
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Two standard sets of criteria are used to evaluate the tumor response of hepatocellular carcinoma (HCC): RECIST (Response Evaluation Criteria in Solid Tumors) and modified RECIST (mRECIST). The purpose was to compare two tumor response evaluation criteria, RECIST version 1.1 and mRECIST, for HCC treated usin...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,多中心研究
doi:10.3109/03009734.2012.729104
更新日期:2013-03-01 00:00:00
abstract::An investigation was made of 150 women who were diagnosed at the Department of Obstetrics and Gynaecology, University Hospital, Uppsala in 1964-68 as having toxaemia of pregnancy. Eleven had eclampsia and the remainder pre-eclampsia. Toxaemia occurred in 0.88% (average) of all parturients during the study period. Some...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737809179108
更新日期:1978-01-01 00:00:00
abstract::One hundred and fifty women with a diagnosis of toxaemia of pregnancy treated in the Department of Obstetrics and Gynaecology, University Hospital, Uppsala between 1964 and 1968 were investigated. One hundred women were still living in the area in 1975 and thus could be restudied. The participation rate was 100% in th...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737809179119
更新日期:1978-01-01 00:00:00
abstract:INTRODUCTION:Research about pregnancy-planning behaviour mostly focuses on women, even though pregnancy planning usually also concerns men. The purpose of this study was to investigate how men plan for family, and to measure their fertility knowledge after having become fathers. MATERIAL AND METHODS:Data were collecte...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2017.1316531
更新日期:2017-06-01 00:00:00
abstract::Background: Although chronic obstructive pulmonary disease (COPD) is a life-limiting disease with a significant symptom burden, the patients are more often referred to nursing homes (NH), than to specialist palliative care (SPC) at the end of life (EOL). This study aimed to compare patients with COPD in SPC with those...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2019.1586803
更新日期:2019-04-01 00:00:00
abstract::Post-heparin plasma hepatic triglyceride lipase (H-TGL) and lipoprotein lipase (LPL) activities were 8-34 and 3.5-21 (range) mu mol/ml/hr respectively in males with normal serum lipid concentrations. In females the corresponding values were 4-25 and 4-16 mu mol/ml/hr. No significant differences were observed between a...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737909179158
更新日期:1979-01-01 00:00:00
abstract::In Uppsala, extensive epidemiological and clinical studies on insulin resistance and diabetes have been ongoing for the past 30 years. A prospective cohort study of men born 1920-24, living in Uppsala County, was initiated during 1969-74 (the Uppsala Longitudinal Study of Adult Men, ULSAM). Risk factors for cardiovasc...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.1517/03009734000000060
更新日期:2000-01-01 00:00:00
abstract::For staging of Hodgkin's disease 45 patients underwent lymphography and abdominal computed tomography (CT); in 31 of them ultrasound examination was also performed. In cases of retroperitoneal lymph node enlargement lymphography and CT are diagnostically equivalent, whereas the poorer resolution of ultrasound reduces ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738409179500
更新日期:1984-01-01 00:00:00
abstract::Local heat trauma was induced in rats with alloxan diabetes of 3 days duration. Zinc and copper concentrations in serum, liver, heart and pancreas were estimated. After traumatization there was a decrease of the serum zinc concentration in all animals. The lowest concentration was found in the diabetic animals. Serum ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179172
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Non-contrast computed tomography (NCT) has become an important diagnostic tool in acute abdominal pain, but the drawback is the increased radiation dose compared to abdominal plain film (APF). PURPOSE:To evaluate whether NCT, including low-dose computed tomography (LDCT, using 50 mAs), provides more diagnos...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903294871
更新日期:2010-05-01 00:00:00
abstract::Thirteen healthy women (age 24-44 yrs) were studied during their menstrual cycle. Samples were taken 2-3 times weekly for six consecutive weeks. Plasma concentrations of oestradiol and progesterone were determined in each blood sample and only women found to be ovulatory were included. From the hormone data the cycles...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738909178559
更新日期:1989-01-01 00:00:00
abstract::A thymolipoma in an 8-year-old boy is reported. The tumour had appeared on a routine chest X-ray as a broadened heart shadow and a peculiar right heart contour. Cardiac hypertrophy was suspected primarily. At thoracotomy a thymic tumour was found. ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179036
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVES:To estimate the possible economic benefit of a sequential testing strategy with NT-proBNP to reduce the number of echocardiographies. METHODS:Retrospective study in a third-party payer perspective. The costs were calculated from three Swedish counties: Blekinge, Östergötland, and Uppland. Two cut-off levels...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.751471
更新日期:2013-05-01 00:00:00
abstract::Although AL amyloidosis usually is a systemic disease, strictly localized AL deposits are not exceptionally rare. Such case reports form a considerable body of published articles. Although both AL amyloidosis types are formed from an N-terminal segment of a monoclonal immunoglobulin light chain, a typical localized AL...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2012.654861
更新日期:2012-05-01 00:00:00
abstract::A material comprising all children in Sweden with acute lymphoblastic leukemia diagnosed in the years 1973-80 was analysed statistically. The total number of children was 505. Studies were made of 38 different variables, using frequency tables, cross tables, life table studies (1) and linear regression analysis accord...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178424
更新日期:1982-01-01 00:00:00
abstract::This paper discusses briefly: analytical quality and its determinants; design of quality assurance procedures on the basis of quality; specifications and quality-cost models; test quality and medical costs; external quality assessment and harmonization of clinical chemical test results; the potential role of computers...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738609178519
更新日期:1986-01-01 00:00:00
abstract::The purpose of this study is to verify that compound muscle action potentials (CMAPs) generated a stationary potential and to examine extension of the CMAPs away from the stimulated muscle. A referential derivation and/or bipolar derivation to record the stationary potentials were carried out following tibial nerve st...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-103
更新日期:2004-01-01 00:00:00
abstract::Fifty-one healthy men, 18 - 19 years of age, with "organic" T wave aberrations (group T) were compared to 112 controls of the same age with normal electrocardiograms (Group A + B). Group T had increased heart rate and higher systolic and diastolic blood pressures. Their lower physical work capacity could be "explained...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179186
更新日期:1980-01-01 00:00:00
abstract::Secondary osteosarcoma arising after the treatment of hematologic malignancies other than Hodgkin's lymphoma is rare. We report two cases of secondary osteosarcoma arising after treatment for childhood hematologic malignancies (non-Hodgkin's lymphoma and lymphoblastic leukemia). A 10-year-old boy, at the age of 3, was...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903177340
更新日期:2009-01-01 00:00:00
abstract::In order to investigate the relevance of the currently used lower reference limit for S-Potassium in Danish hospital laboratories, analytical bias in the measurement of S-Potassium was compared with the lower reference limit in each of 52 Danish hospital laboratories. The acceptable bias range was estimated according ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739309179337
更新日期:1993-01-01 00:00:00
abstract::Isokinetic torque of the knee and elbow during maximal extension and flexion and isometric strength of the handgrip, as well as balance and some circulatory variables, were tested in 37 patients one year after an acute stroke. Correlations with locomotion, household work and other activities of daily living (ADL) were...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178405
更新日期:1982-01-01 00:00:00
abstract::This study was undertaken to evaluate the utility of a modified technique of triplex scanning of the lower extremity arteries in 20 subjects without any clinical signs of arterial disease. The distal aorta and iliac arteries were examined with the subject in supine position and lying slightly on the opposite side. By ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739609178917
更新日期:1996-01-01 00:00:00
abstract::Diabetes in the mother may cause disturbances in the chondrocyte development in the embryo. A rat model was used to investigate whether this was reflected in the production of proteoglycans by cells from two embryonic regions. One of these regions is resistant (limb bud) and the other susceptible (mandibular arch) to ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739009178574
更新日期:1990-01-01 00:00:00
abstract::Bile salt sulphation in primary biliary cirrhosis was studied by measurements of the liver bile salt sulphotransferase levels in 16 patients. Although the enzyme activity varied among the patients it did not correlate with the severity of cholestasis. Furthermore, the mean bile salt sulphotransferase magnitude in pati...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738309178432
更新日期:1983-01-01 00:00:00
abstract::Twenty-seven women with secondary amenorrhoea have been treated with pulsatile subcutaneous luteinising hormone releasing hormone (LHRH). Serial ultrasonic observations of increasing follicular diameters and changes in the size of the uterus have been recorded. The rate of the increase of the diameter of dominant foll...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738409178460
更新日期:1984-01-01 00:00:00