Abstract:
:The use of biomarkers of microvascular structure and function from perfusion and permeability imaging is now well established in neuro-oncological research. There remain significant challenges to be overcome before these techniques and related biomarkers can find general clinical acceptance. Core to this is the standardization of acquisition and processing protocols for robust use across multiple clinical sites. The potential clinical benefits of these approaches are already becoming clear, particularly in the setting of novel antiangiogenic therapies. With an increasing body of evidence in the scientific literature, and with a steadily falling barrier to entry, the coming decade should see rapid developments in imaging biomarkers, and facilitate their transition into routine clinical practice.
journal_name
Neuroimaging Clin N Amjournal_title
Neuroimaging clinics of North Americaauthors
Thompson G,Mills SJ,Stivaros SM,Jackson Adoi
10.1016/j.nic.2010.04.008subject
Has Abstractpub_date
2010-08-01 00:00:00pages
337-53issue
3eissn
1052-5149issn
1557-9867pii
S1052-5149(10)00043-2journal_volume
20pub_type
杂志文章,评审abstract::Since acute stroke and transient ischemic attack (TIA) are disruptions of brain hemodynamics, perfusion neuroimaging might be of clinical utility. Recently, arterial spin labeling (ASL), a noncontrast perfusion method, has become clinically feasible. It has advantages compared to contrast bolus perfusion-weighted imag...
journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1997-05-01 00:00:00
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journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
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journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2019.03.008
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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abstract::Acute disseminated encephalomyelitis (ADEM) is a monophasic demyelinating disease of the central nervous system typically affecting the gray and the white matter of the brain and spinal cord in multiple locations. In the acute stages, ADEM is characterized histologically by perivenous edema, demyelination, and infiltr...
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