Imaging of brain tumors: perfusion/permeability.

Abstract:

:The use of biomarkers of microvascular structure and function from perfusion and permeability imaging is now well established in neuro-oncological research. There remain significant challenges to be overcome before these techniques and related biomarkers can find general clinical acceptance. Core to this is the standardization of acquisition and processing protocols for robust use across multiple clinical sites. The potential clinical benefits of these approaches are already becoming clear, particularly in the setting of novel antiangiogenic therapies. With an increasing body of evidence in the scientific literature, and with a steadily falling barrier to entry, the coming decade should see rapid developments in imaging biomarkers, and facilitate their transition into routine clinical practice.

journal_name

Neuroimaging Clin N Am

authors

Thompson G,Mills SJ,Stivaros SM,Jackson A

doi

10.1016/j.nic.2010.04.008

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

337-53

issue

3

eissn

1052-5149

issn

1557-9867

pii

S1052-5149(10)00043-2

journal_volume

20

pub_type

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