当前位置： SCI文献检索 > COMPUTATIONAL BIOLOGY AND CHEMISTRY期刊下所有文献 > Stable feature selection for biomarker discovery.

Stable feature selection for biomarker discovery.

Abstract：

:Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered. It is only until recently that this issue has received more and more attention. In this article, we review existing stable feature selection methods for biomarker discovery using a generic hierarchical framework. We have two objectives: (1) providing an overview on this new yet fast growing topic for a convenient reference; (2) categorizing existing methods under an expandable framework for future research and development.

journal_name

Comput Biol Chem

journal_title

Computational biology and chemistry

authors

He Z,Yu W

doi

10.1016/j.compbiolchem.2010.07.002

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

215-25

issue

4

eissn

1476-9271

issn

1476-928X

pii

S1476-9271(10)00050-2

journal_volume

34

pub_type

杂志文章,评审

相关文献

COMPUTATIONAL BIOLOGY AND CHEMISTRY文献大全
  • L2,1-Extreme Learning Machine: An Efficient Robust Classifier for Tumor Classification.

    abstract：:With the development of cancer research, various gene expression datasets containing cancer information show an explosive growth trend. In addition, due to the continuous maturity of single-cell RNA sequencing (scRNA-seq) technology, the protein information and pedigree information of a single cell are also continuous...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2020.107368

    authors： Ren LR,Gao YL,Liu JX,Zhu R,Kong XZ

    更新日期：2020-12-01 00:00:00

  • Dynamic characterization of HLA-B*44 Alleles: A comparative molecular dynamics simulation study.

    abstract：:Human Leukocyte Antigens (HLA) are highly polymorphic proteins that play a key role in the immune system. HLA molecule is present on the cell membrane of antigen-presenting cells of the immune system and presents short peptides, originating from the proteins of invading pathogens or self-proteins, to the T-cell Recept...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2016.02.019

    authors： Ozbek P

    更新日期：2016-06-01 00:00:00

  • FWAVina: A novel optimization algorithm for protein-ligand docking based on the fireworks algorithm.

    abstract：:Protein-ligand docking is an essential process that has accelerated drug discovery. How to accurately and effectively optimize the predominant position and orientation of ligands in the binding pocket of a target protein is a major challenge. This paper proposed a novel ligand binding pose search method called FWAVina...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2020.107363

    authors： Li J,Song Y,Li F,Zhang H,Liu W

    更新日期：2020-10-01 00:00:00

  • The interactome of CCT complex - A computational analysis.

    abstract：:The eukaryotic chaperonin, CCT (Chaperonin Containing TCP1 or TriC-TCP-1 Ring Complex) has been subjected to physical and genetic analyses in S. cerevisiae which can be extrapolated to human CCT (hCCT), owing to its structural and functional similarities with yeast CCT (yCCT). Studies on hCCT and its interactome acqui...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2016.09.002

    authors： Narayanan A,Pullepu D,Kabir MA

    更新日期：2016-10-01 00:00:00

  • Biochemical and computational insights of adenosine deaminase inhibition by Epigallocatechin gallate.

    abstract：:Epigallocatechin gallate, a flavonoid from Camellia sinensis possess various pharmacological activities such as anticancer, antimicrobial and antioxidant etc. Adenosine deaminase, (ADA), is a key enzyme involved in the purine metabolism, the inhibitors of which is being considered as highly promising candidate for the...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2019.107111

    authors： K G A,C S S,J A,C S

    更新日期：2019-12-01 00:00:00

  • Understanding the role of the topology in protein folding by computational inverse folding experiments.

    abstract：:Recent studies suggest that protein folding should be revisited as the emergent property of a complex system and that the nature allows only a very limited number of folds that seem to be strongly influenced by geometrical properties. In this work we explore the principles underlying this new view and show how helical...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2008.03.015

    authors： Mucherino A,Costantini S,di Serafino D,D'Apuzzo M,Facchiano A,Colonna G

    更新日期：2008-08-01 00:00:00

  • Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design.

    abstract：:3CL proteases (3CLpro) are only found in RNA viruses and have a central role in polyprotein processing during replication. Therefore, 3CLpro has emerged as promising drug target for therapeutic treatment of infections caused by Coronaviruses. In the light of the recent major outbreak of the SARS-CoV-2 virus and the co...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2020.107351

    authors： Meyer-Almes FJ

    更新日期：2020-10-01 00:00:00

  • Effects of DNA secondary structure on oligonucleotide probe binding efficiency.

    abstract：:Secondary structure motifs in nucleic acid probes generally impair intended hybridization reactions and so efforts to predict and avoid such structures are commonly employed in probe design schemes. Another key facet of probe design that has received much less attention, however, is that secondary structure at targete...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2005.09.002

    authors： Koehler RT,Peyret N

    更新日期：2005-12-01 00:00:00

  • 1,3-Oxazole derivatives of cytisine as potential inhibitors of glutathione reductase of Candida spp.: QSAR modeling, docking analysis and experimental study of new anti-Candida agents.

    abstract：:Natural products as well as their derivatives play a significant role in the discovery of new biologically active compounds in the different areas of our life especially in the field of medicine. The synthesis of compounds produced from natural products including cytisine is one approach for the wider use of natural s...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2020.107407

    authors： Metelytsia LO,Trush MM,Kovalishyn VV,Hodyna DM,Kachaeva MV,Brovarets VS,Pilyo SG,Sukhoveev VV,Tsyhankov SA,Blagodatnyi VM,Semenyuta IV

    更新日期：2020-11-05 00:00:00

  • Synthesis, biological evaluation, and computational studies of novel fused six-membered O-containing heterocycles as potential acetylcholinesterase inhibitors.

    abstract：:An efficient, borax-catalyzed protocol for the synthesis of novel 4-aryl-substituted-4H-pyran derivatives fused to α-pyrone ring in a one-pot is described. By this achievement, some novel 4-aryl substituted 4H-pyrans fused to the α-pyrone ring as potential acetylcholinesterase inhibitors (AChEIs) with good to excellen...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2019.04.004

    authors： Pourshojaei Y,Abiri A,Eskandari R,Dourandish F,Eskandari K,Asadipour A

    更新日期：2019-06-01 00:00:00

  • Phosphorylation mapping of laminin α1-chain: Kinases in association with active sites.

    abstract：:Laminin-111 is a trimeric glycoprotein of the extracellular matrix (ECM) that holds a significant role in cell adhesion, migration and differentiation. Laminin-111 is the most studied laminin isoform, composed of three chains; α1, β1 and γ1. Phosphorylation is the most common eukaryotic post - translational modificati...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2019.04.012

    authors： Galliou PA,Verrou KM,Koliakos G

    更新日期：2019-06-01 00:00:00

  • Aconitum and Delphinium sp. alkaloids as antagonist modulators of voltage-gated Na+ channels. AM1/DFT electronic structure investigations and QSAR studies.

    abstract：:Early pharmacological studies of Aconitum and Delphinium sp. alkaloids suggested that these neurotoxins act at site 2 of voltage-gated Na(+) channel and allosterically modulate its function. Understanding structural requirements for these compounds to exhibit binding activity at voltage-gated Na(+) channel has been im...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2007.10.003

    authors： Turabekova MA,Rasulev BF,Levkovich MG,Abdullaev ND,Leszczynski J

    更新日期：2008-04-01 00:00:00

  • A novel k-word relative measure for sequence comparison.

    abstract：:In order to extract phylogenetic information from DNA sequences, the new normalized k-word average relative distance is proposed in this paper. The proposed measure was tested by discriminate analysis and phylogenetic analysis. The phylogenetic trees based on the Manhattan distance measure are reconstructed with k ran...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2014.10.007

    authors： Tang J,Hua K,Chen M,Zhang R,Xie X

    更新日期：2014-12-01 00:00:00

  • Exploring two-dimensional graphene and boron-nitride as potential nanocarriers for cytarabine and clofarabine anti-cancer drugs.

    abstract：:Development in two-dimensional (2D) drug-delivery materials have quickly translated into biological and pharmacological fields. In this present work, pristine graphene (PG) and hexagonal boron nitride (h-BN) sheets are explored as a drug carrier for cytarabine (CYT) and clofarabine (CLF) anti-cancer drugs using densit...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2020.107334

    authors： Saravanan V,Rajamani A,Subramani M,Ramasamy S

    更新日期：2020-10-01 00:00:00

  • Identification of Casiopeina II-gly secondary targets through a systems pharmacology approach.

    abstract：:Casiopeinas are a group of copper-based compounds designed to be used as less toxic, more efficient chemotherapeutic agents. In this study, we analyzed the in vitro effects of Casiopeina II-gly on the expression of canonical biological pathways. Using microarray data from HeLa cell lines treated with Casiopeina II-gly...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2018.11.021

    authors： de Anda-Jáuregui G,Espinal-Enríquez J,Hur J,Alcalá-Corona SA,Ruiz-Azuara L,Hernández-Lemus E

    更新日期：2019-02-01 00:00:00

  • ScGSLC: An unsupervised graph similarity learning framework for single-cell RNA-seq data clustering.

    abstract：:Accurate clustering of cells from single-cell RNA sequencing (scRNA-seq) data is an essential step for biological analysis such as putative cell type identification. However, scRNA-seq data has high dimension and high sparsity, which makes traditional clustering methods less effective to reflect the similarity between...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2020.107415

    authors： Li J,Jiang W,Han H,Liu J,Liu B,Wang Y

    更新日期：2020-11-18 00:00:00

  • From NGS assembly challenges to instability of fungal mitochondrial genomes: A case study in genome complexity.

    abstract：:The presence of repetitive or non-unique DNA persisting over sizable regions of a eukaryotic genome can hinder the genome's successful de novo assembly from short reads: ambiguities in assigning genome locations to the non-unique subsequences can result in premature termination of contigs and thus overfragmented assem...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2016.02.016

    authors： Misas E,Muñoz JF,Gallo JE,McEwen JG,Clay OK

    更新日期：2016-04-01 00:00:00

  • On application of directons to functional classification of genes in prokaryotes.

    abstract：:Functional classification of genes represents one of the most basic problems in genome analysis and annotation. Our analysis of some of the popular methods for functional classification of genes shows that these methods are not always consistent with each other and may not be specific enough for high-resolution gene f...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2008.02.007

    authors： Wu H,Mao F,Olman V,Xu Y

    更新日期：2008-06-01 00:00:00

  • In silico analyses of a new group of fungal and plant RecQ4-homologous proteins.

    abstract：:Bacterial and eukaryotic RecQ helicases comprise a family of homologous proteins necessary for maintaining genomic integrity during the cell cycle and DNA repair. There is one known bacterial RecQ helicase, and five eukaryotic RecQ helicases that have been described: RecQ1p, RecQ4p, RecQ5p, Bloom, and Werner. While th...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2008.07.005

    authors： Barea F,Tessaro S,Bonatto D

    更新日期：2008-10-01 00:00:00

  • The aspartate aminotransferase-like domain of Firmicutes MocR transcriptional regulators.

    abstract：:Bacterial MocR transcriptional regulators possess an N-terminal DNA-binding domain containing a conserved helix-turn-helix module and an effector-binding and/or oligomerization domain at the C-terminus, homologous to fold type-I pyridoxal 5'-phosphate (PLP) enzymes. Since a comprehensive structural analysis of the Moc...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2015.05.003

    authors： Milano T,Contestabile R,Lo Presti A,Ciccozzi M,Pascarella S

    更新日期：2015-10-01 00:00:00

  • Semantically predicting protein functions based on protein functional connectivity.

    abstract：BACKGROUND:The current availability of public protein-protein interaction (PPI) databases which are usually modelled as PPI networks has led to the rapid development of protein function prediction approaches. The existing network-based prediction approaches mainly focus on the topological similarities between immediate...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2013.01.002

    authors： Zhu W,Hou J,Chen YP

    更新日期：2013-06-01 00:00:00

  • Physical quantity of residue electrostatic energy in flavin mononucleotide binding protein dimer.

    abstract：:The electrostatic (ES) energy of each residue was for the first time quantitatively evaluated in a flavin mononucleotide binding protein (FBP). A residue electrostatic energy (RES) was obtained as the sum of the ES energies between atoms in each residue and all other atoms in the FBP dimer using atomic coordinates obt...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2018.01.001

    authors： Nunthaboot N,Nueangaudom A,Lugsanangarm K,Pianwanit S,Kokpol S,Tanaka F

    更新日期：2018-02-01 00:00:00

  • QSAR study of pyrazolo[4,3-e][1,2,4]triazine sulfonamides against tumor-associated human carbonic anhydrase isoforms IX and XII.

    abstract：:The QSAR models for a set of pyrazolo[4,3-e][1,2,4]triazines incorporating benzenesulfonamide moiety combined directly with the heterocyclic ring or by NH linkage were generated. The inhibitory potency of compounds against human carbonic anhydrase isoforms IX and XII and antiproliferative activity against human MCF-7 ...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2017.09.006

    authors： Matysiak J,Skrzypek A,Tarasiuk P,Mojzych M

    更新日期：2017-12-01 00:00:00

  • The complex task of choosing a de novo assembly: lessons from fungal genomes.

    abstract：:Selecting the values of parameters used by de novo genomic assembly programs, or choosing an optimal de novo assembly from several runs obtained with different parameters or programs, are tasks that can require complex decision-making. A key parameter that must be supplied to typical next generation sequencing (NGS) a...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2014.08.014

    authors： Gallo JE,Muñoz JF,Misas E,McEwen JG,Clay OK

    更新日期：2014-12-01 00:00:00

  • WITHDRAWN: Identification of microRNA precursor based on gapped n-tuple structure status composition kernel.

    abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

    journal_title：Computational biology and chemistry

    pub_type： 撤回出版物

    doi：10.1016/j.compbiolchem.2016.02.010

    authors： Liu B,Fang L

    更新日期：2016-02-17 00:00:00

  • In silico study of porphyrin-anthraquinone hybrids as CDK2 inhibitor.

    abstract：:Cyclin-Dependent Kinases (CDKs) are known to play crucial roles in controlling cell cycle progression of eukaryotic cell and inhibition of their activity has long been considered as potential strategy in anti-cancer drug research. In the present work, a series of porphyrin-anthraquinone hybrids bearing meso-substituen...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2016.12.005

    authors： Arba M,Ihsan S,Ramadhan OA,Tjahjono DH

    更新日期：2017-04-01 00:00:00

  • Inhibitory activity of hibifolin on adenosine deaminase- experimental and molecular modeling study.

    abstract：:Adenosine deaminase (ADA) is an enzyme involved in purine metabolism. ADA converts adenosine to inosine and liberates ammonia. Because of their critical role in the differentiation and maturation of cells, the regulation of ADA activity is considered as a potential therapeutic approach to prevent malignant and inflamm...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2016.08.005

    authors： Arun KG,Sharanya CS,Sandeep PM,Sadasivan C

    更新日期：2016-10-01 00:00:00

  • Automated prediction of three-way junction topological families in RNA secondary structures.

    abstract：:We present an algorithm for automatically predicting the topological family of any RNA three-way junction, given only the information from the secondary structure: the sequence and the Watson-Crick pairings. The parameters of the algorithm have been determined on a data set of 33 three-way junctions whose 3D conformat...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2011.11.001

    authors： Lamiable A,Barth D,Denise A,Quessette F,Vial S,Westhof E

    更新日期：2012-04-01 00:00:00

  • Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations.

    abstract：:Our ability to detect differentially expressed genes in a microarray experiment can be hampered when the number of biological samples of interest is limited. In this situation, we propose the use of information from self-self hybridizations to acuminate our inference of differential expression. A unified modelling str...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2007.03.005

    authors： Gusnanto A,Tom B,Burns P,Macaulay I,Thijssen-Timmer DC,Tijssen MR,Langford C,Watkins N,Ouwehand W,Berzuini C,Dudbridge F

    更新日期：2007-06-01 00:00:00

  • Computational characterization and design of SARS coronavirus receptor recognition and antibody neutralization.

    abstract：:The sequential determination of crystal structures of the SARS coronavirus spike receptor-binding domain (RBD) in complex with its cellular receptor or neutralizing antibody opened a door for the design and development of antiviral competitive inhibitors. Based on those complex structures, we conduct computational cha...

    journal_title：Computational biology and chemistry

    pub_type： 杂志文章

    doi：10.1016/j.compbiolchem.2007.02.005

    authors： Zhang Y,Zheng N,Zhong Y

    更新日期：2007-04-01 00:00:00