Prevalence of daily medication adherence among children with sickle cell disease: a 1-year retrospective cohort analysis.

Abstract:

:The objective of this study is to determine the prevalence of adherence to daily medications among children with sickle cell disease (SCD). Prescription records for 12 months were obtained from participants who had insurance in a Medicaid-based single health maintenance organization. Adherence was measured as a ratio between the number of expected days and the observed days between two refill periods for daily medications. A total of 93 children were studied. The average refill prescription rate was 58.4%. More formal strategies are required to identify barriers to prescription refills among children with SCD.

journal_name

Pediatr Blood Cancer

journal_title

Pediatric blood & cancer

authors

Patel NG,Lindsey T,Strunk RC,DeBaun MR

doi

10.1002/pbc.22605

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

554-6

issue

3

eissn

1545-5009

issn

1545-5017

journal_volume

55

pub_type

杂志文章
  • Influenza-associated morbidity in children with cancer.

    abstract:BACKGROUND:The clinical impact of influenza in children undergoing therapy for cancer is not well-described in the literature. PROCEDURE:Laboratory-documented influenza infection in pediatric oncology patients cared for in a single regional pediatric medical center between July 2000 and June 2005 was identified by rev...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/pbc.21472

    authors: Tasian SK,Park JR,Martin ET,Englund JA

    更新日期:2008-05-01 00:00:00

  • Age dependency of primary tumor sites and metastases in patients with Ewing sarcoma.

    abstract:BACKGROUND:The median age of patients with Ewing sarcoma (EwS) at diagnosis is around 14-15 years. Older age is associated with a worse outcome. The correlation of age at diagnosis on sites of disease has not been fully described. OBJECTIVE:The goal of this study was to evaluate the differences in sites of primary tum...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.27251

    authors: Worch J,Ranft A,DuBois SG,Paulussen M,Juergens H,Dirksen U

    更新日期:2018-09-01 00:00:00

  • Late effects of total body irradiation and hematopoietic stem cell transplant in children under 3 years of age.

    abstract:BACKGROUND:Total body irradiation (TBI) is an important component of hematopoietic stem cell transplant (SCT) for pediatric malignancies. With increasing survival rates, late effects of SCT become more important. Younger children may be at particular risk of late effects of radiation and SCT. METHODS:We retrospectivel...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.24252

    authors: Mulcahy Levy JM,Tello T,Giller R,Wilkening G,Quinones R,Keating AK,Liu AK

    更新日期:2013-04-01 00:00:00

  • How I approach expressing condolences and longitudinal remembering to a family after the death of a child.

    abstract::Bereaved families fear their child being forgotten by those who knew their loved child, including their child's oncology team. Thoughtfully timed, family-centric condolences shared by pediatric oncology team members have the potential to extend our compassion and kindness toward a family during the darkness of grief. ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.27489

    authors: Weaver MS,Lichtenthal WG,Larson K,Wiener L

    更新日期:2019-02-01 00:00:00

  • Safety and efficacy of high dose intravenous desferrioxamine for reduction of iron overload in sickle cell disease.

    abstract:BACKGROUND:Patients with sickle cell disease (SCD) receiving chronic blood transfusions are at risk of developing iron overload and organ toxicity. Chelation therapy with either subcutaneous (SQ) desferrioxamine (DFO) or oral deferasirox is effective in preventing and reducing iron overload but poses significant challe...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.22660

    authors: Kalpatthi R,Peters B,Kane I,Holloman D,Rackoff E,Disco D,Jackson S,Laver JH,Abboud MR

    更新日期:2010-12-15 00:00:00

  • Use of infliximab-daclizumab combination for the treatment of acute and chronic graft-versus-host disease of the liver and gut.

    abstract::Infliximab-daclizumab was used to treat acute and chronic liver and gut graft-versus-host disease (GVHD) in two children after standard immunosuppressive therapy failed. Infliximab (10 mg/kg weekly, 4 doses) and daclizumab (1 mg/kg, days 1, 4, 8, 15, and 22) were given over 1 month. In case 1, grade 2 chronic GVHD of ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审

    doi:10.1002/pbc.20648

    authors: Rodriguez V,Anderson PM,Trotz BA,Arndt CA,Allen JA,Khan SP

    更新日期:2007-08-01 00:00:00

  • Markers of bone turnover are associated with growth and development in young subjects with sickle cell anemia.

    abstract::Children with sickle cell anemia (SCA) have low bone mass though bone turnover has not been well described. In this study, growth and pubertal development were assessed twice, 1 year apart, in 80 young subjects with type-SS SCA, while whole body bone mineral content (BMC) and density where measured in a subset (n = 46...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.21147

    authors: Fung EB,Kawchak DA,Zemel BS,Rovner AJ,Ohene-Frempong K,Stallings VA

    更新日期:2008-03-01 00:00:00

  • Long-term outcomes of children with extracutaneous juvenile xanthogranulomas in Japan.

    abstract:BACKGROUND:Juvenile xanthogranuloma (JXG) is the most common non-Langerhans cell histiocytosis in children. The mortality and morbidity of JXG with extracutaneous lesions remain unclear. METHODS:Data of patients aged < 18 years who were diagnosed with JXG between 2001 and 2010 were retrospectively collected through a ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28381

    authors: Maeda M,Morimoto A,Shioda Y,Asano T,Koga Y,Nakazawa Y,Kanegane H,Kudo K,Ohga S,Ishii E,Histiocytosis Study Group of the Japanese Society of Pediatric Hematology\/Oncology.

    更新日期:2020-07-01 00:00:00

  • Impact of SLCO1B1 521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high-dose methotrexate.

    abstract:BACKGROUND:Recent studies suggest that SLCO1B1 c.521T > C variant decreases the clearance of methotrexate (MTX) and elevates its plasma concentration, hence leucovorin doses may need to be adjusted. However, high leucovorin doses may affect the cure rate in childhood acute lymphoblastic leukemia (ALL). Hitherto neither...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25191

    authors: Zhang HN,He XL,Wang C,Wang Y,Chen YJ,Li JX,Niu CH,Gao P

    更新日期:2014-12-01 00:00:00

  • A man-made disease: Fetal neonatal alloimmune thrombocytopenia due to incompatibility between oocyte donor and gestational mother.

    abstract::The incompatibility causing fetal and neonatal alloimmune thrombocytopenia (FNAIT) results from a fetus inheriting a paternal human platelet antigen (HPA), which is different from the maternal HPA. We present a unique case of FNAIT in a pregnancy involving an oocyte recipient mother with Turner syndrome. This is the f...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.26447

    authors: Barg AA,Ifrah AD,Strauss T,Simchen MJ,Orvieto R,Rosenberg N,Kenet G

    更新日期:2017-08-01 00:00:00

  • Intensified Chemotherapy With Dexrazoxane Cardioprotection in Newly Diagnosed Nonmetastatic Osteosarcoma: A Report From the Children's Oncology Group.

    abstract:BACKGROUND:Although chemotherapy has improved outcome of osteosarcoma, 30-40% of patients succumb to this disease. Survivors experience substantial morbidity and mortality from anthracycline-induced cardiotoxicity. We hypothesized that the cardioprotectant dexrazoxane would (i) support escalation of the cumulative doxo...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25753

    authors: Schwartz CL,Wexler LH,Krailo MD,Teot LA,Devidas M,Steinherz LJ,Goorin AM,Gebhardt MC,Healey JH,Sato JK,Meyers PA,Grier HE,Bernstein ML,Lipshultz SE

    更新日期:2016-01-01 00:00:00

  • High cumulative rate of secondary leukemia after continuous etoposide treatment for solid tumors in children and young adults.

    abstract:BACKGROUND:In a national pediatric case-control study, we observed a very high relative risk of leukemia in patients who had received continuous etoposide (CE) over 6 months or more, but we could not estimate the absolute risk. The purpose of the present study was to estimate this absolute risk after CE. PROCEDURES:We...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20380

    authors: Le Deley MC,Vassal G,Taïbi A,Shamsaldin A,Leblanc T,Hartmann O

    更新日期:2005-07-01 00:00:00

  • Gastrostomy tube use in children with cancer.

    abstract::Children with cancer are at risk of malnutrition, which can impair critical childhood processes of growth and development and contribute to poor health outcomes. Enteral nutrition can effectively ameliorate malnutrition or weight loss in children with cancer; however, published nutrition support algorithms contain min...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.27702

    authors: McGrath KH,Hardikar W

    更新日期:2019-07-01 00:00:00

  • EBV lymphoproliferative disease of host origin after haploidentical stem cell transplantation.

    abstract::Post-transplant lymphoproliferative disease (PTLPD), due to the reactivation of Epstein-Barr virus (EBV), is a serious complication. The risk of the disorder increases with T-cell depletion methods, mismatched hematopoietic stem cell transplantation (HSCT), graft-versus-host disease (GVHD), and immunosuppression. In c...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20710

    authors: Kasow KA,Leung W,Horwitz EM,Woodard P,Handgretinger R,Hale GA

    更新日期:2007-11-01 00:00:00

  • New targets for antibody therapy of pediatric B cell lymphomas.

    abstract::Antibody therapy has become standard of care for adult B cell lymphoma patients. It is a potentially less toxic and more targeted approach for lymphoma therapy and should therefore be applied to treat pediatric B cell lymphoma patients as well. In pediatric lymphoma patients, however, clinical experience with monoclon...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审

    doi:10.1002/pbc.25193

    authors: van Vuren A,Meyer-Wentrup F

    更新日期:2014-12-01 00:00:00

  • Higher plasma asparaginase activity after intramuscular than intravenous Erwinia asparaginase.

    abstract::It is unclear if dosing intervals for Erwinase can be extended with intramuscular (i.m.) versus intravenous (i.v.) dosing. Children with acute lymphoblastic leukemia received Erwinase at 30 000-42 000 IU/m2 i.v. or i.m. I.m. Erwinase (n = 22) achieved activity above 0.1 IU/mL for longer than i.v. Erwinase (n = 33) (3....

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28244

    authors: Panetta JC,Liu Y,Swanson HD,Karol SE,Pui CH,Inaba H,Jeha S,Relling MV

    更新日期:2020-07-01 00:00:00

  • A unique phenotype of T-cell acute lymphoblastic leukemia in a patient with GATA2 haploinsufficiency.

    abstract::Germline or acquired mutations involving the GATA-binding protein gene (GATA2) have been linked to a variety of clinical conditions. In addition, patients harboring GATA2 mutations have a striking predisposition to develop myeloid malignancies, such as myelodysplastic syndrome or acute myeloid leukemia, but not acute ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.27649

    authors: Esparza O,Xavier AC,Atkinson TP,Hill BC,Whelan K

    更新日期:2019-06-01 00:00:00

  • Medical and rehabilitation interventions in pediatric central nervous system radiation necrosis: A case report.

    abstract::Radiation necrosis is a potentially debilitating side effect of therapy necessary to treat pediatric central nervous system tumors. Clinical signs of cerebral radiation necrosis (CRN) are similar to symptoms of disease progression and require close monitoring. The case of an infant diagnosed with a malignant rhabdoid ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28705

    authors: L'Hotta AJ,Thomas KM,Milgrom SA,Hemenway MS,Levy JMM

    更新日期:2021-01-01 00:00:00

  • Long-term outcomes of Group D eyes in bilateral retinoblastoma patients treated with chemoreduction and low-dose IMRT salvage.

    abstract:BACKGROUND:To evaluate outcomes of Group D eyes of bilateral retinoblastoma patients treated with primary chemoreduction and external beam radiation as salvage. PROCEDURE:Retrospective chart review of patients diagnosed with bilateral retinoblastoma and designated Group D in at least one eye from January 1, 2000 to De...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.24303

    authors: Berry JL,Jubran R,Kim JW,Wong K,Bababeygy SR,Almarzouki H,Lee TC,Murphree AL

    更新日期:2013-04-01 00:00:00

  • Reproductive intentions in mothers of young children with sickle cell disease.

    abstract:BACKGROUND:Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy associated with morbidity and mortality. We sought to understand family planning intentions of parents of young children with SCD including the awareness of three reproductive options (adoption, in vitro fertilization with egg/sperm donatio...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28227

    authors: Schultz CL,Tchume-Johnson T,Jackson T,Enninful-Eghan H,Schapira MM,Smith-Whitley K

    更新日期:2020-05-01 00:00:00

  • Physician Perspectives on Palliative Care for Children With Neuroblastoma: An International Context.

    abstract:BACKGROUND:Studies have shown that children with cancer globally lack access to palliative care. Little is known regarding physicians' perceptions of palliative care, treatment access, and self-reported competence in providing palliative care. PROCEDURE:Members of the Global Neuroblastoma Network (online tumor board) ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25900

    authors: Balkin EM,Thompson D,Colson KE,Lam CG,Matthay KK

    更新日期:2016-05-01 00:00:00

  • Clinical practice guideline improves the treatment of sickle cell disease vasoocclusive pain.

    abstract:BACKGROUND:Pain is the most common complication of sickle cell disease requiring emergency department (ED) visits and hospitalization. A Clinical Practice Guideline (CPG) to manage acute sickle cell pain offers clinicians a standardized approach for the provision of evidence-based, cost-effective care. After CPG implem...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.21847

    authors: Morrissey LK,Shea JO,Kalish LA,Weiner DL,Branowicki P,Heeney MM

    更新日期:2009-03-01 00:00:00

  • Imatinib cessation in children and adolescents with chronic myeloid leukemia in chronic phase.

    abstract::Imatinib can be safely discontinued in adults with chronic myeloid leukemia (CML) where there is a prolonged complete molecular response (CMR). No data are available in the pediatric population. Six children with CML discontinued imatinib by themselves. Only three of them were in CMR but for <2 years. A significant in...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.24521

    authors: Millot F,Claviez A,Leverger G,Corbaciglu S,Groll AH,Suttorp M

    更新日期:2014-02-01 00:00:00

  • Yield of Urinalysis Screening in Pediatric Cancer Survivors.

    abstract:BACKGROUND:The Children's Oncology Group (COG) publishes consensus guidelines with screening recommendations for early identification of treatment-related morbidities among childhood cancer survivors. We sought to estimate the yield of recommended yearly urinalysis screening for genitourinary complications as per Versi...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/pbc.25897

    authors: Ramirez MD,Mertens AC,Esiashvili N,Meacham LR,Wasilewski-Masker K

    更新日期:2016-05-01 00:00:00

  • An investigation of toxicities and survival in Hispanic children and adolescents with ALL: Results from the Dana-Farber Cancer Institute ALL Consortium protocol 05-001.

    abstract:PURPOSE:This study compared the relative incidence of treatment-related toxicities and the event-free and overall survival between Hispanic and non-Hispanic children undergoing therapy for acute lymphoblastic leukemia (ALL) on Dana-Farber Cancer Institute ALL Consortium protocol 05-001. PATIENTS AND METHODS:Secondary ...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/pbc.26871

    authors: Kahn JM,Cole PD,Blonquist TM,Stevenson K,Jin Z,Barrera S,Davila R,Roberts E,Neuberg DS,Athale UH,Clavell LA,Laverdiere C,Leclerc JM,Michon B,Schorin MA,Welch JJG,Sallan SE,Silverman LB,Kelly KM

    更新日期:2018-03-01 00:00:00

  • Osteosarcoma in patients younger than 12 years old without metastases have similar prognosis as adolescent and young adults.

    abstract:BACKGROUND:Childhood cancer is relatively rare and tends to present specific age distribution, as a prognostic factor for some of these diseases. Information on how young age affects prognosis, response to chemotherapy, and local control options in children versus AYA with osteosarcoma (OST) is minimal. METHODS:In ord...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25459

    authors: Eleutério SJ,Senerchia AA,Almeida MT,Da Costa CM,Lustosa D,Calheiros LM,Barreto JH,Brunetto AL,Macedo CR,Petrilli AS

    更新日期:2015-07-01 00:00:00

  • Use of RNA interference to elucidate the effect of MYCN on cell cycle in neuroblastoma.

    abstract:BACKGROUND:MYCN amplification marks poor prognosis in neuroblastoma (NB) tumors. In evaluating the mechanisms by which retinoic acid (RA) or nerve growth factor (NGF) decrease cell number in MYCN amplified NB cells, we have identified a number of proteins whose expression either decreases (E2F, CDC2, CDK6, cyclin depen...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.21195

    authors: Woo CW,Tan F,Cassano H,Lee J,Lee KC,Thiele CJ

    更新日期:2008-02-01 00:00:00

  • Household material hardship in families of children post-chemotherapy.

    abstract::Poverty is an important patient-reported outcome of therapy and a potential predictor of outcome disparities in pediatric cancer. We previously identified that nearly 30% of pediatric cancer families experience household material hardship (HMH), a concrete measure of poverty including food, energy, or housing insecuri...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/pbc.26743

    authors: Bilodeau M,Ma C,Al-Sayegh H,Wolfe J,Bona K

    更新日期:2018-01-01 00:00:00

  • Medication errors on oral chemotherapy in children with acute lymphoblastic leukemia in a developing country.

    abstract:BACKGROUND:Medication errors occur universally. Inappropriate administration of chemotherapy drugs can have adverse effects in cancer patients. Our objective was to assess the rate and type of medication errors in children with acute lymphoblastic leukemia (ALL) receiving oral chemotherapy in outpatient setting. PROCE...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25203

    authors: Oberoi S,Trehan A,Marwaha RK

    更新日期:2014-12-01 00:00:00

  • Do pregnancy characteristics contribute to rising childhood cancer incidence rates in the United States?

    abstract:BACKGROUND:Since 1975, childhood cancer incidence rates have gradually increased in the United States; however, few studies have conducted analyses across time to unpack this temporal rise. The aim of this study was to test the hypothesis that increasing cancer incidence rates are due to secular trends in pregnancy cha...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.26888

    authors: Kehm RD,Osypuk TL,Poynter JN,Vock DM,Spector LG

    更新日期:2018-03-01 00:00:00