Recombinant human epidermal growth factor (rhEGF) protects radiation-induced intestine injury in murine system.

abstract：:The aim of the study was to compare clinical outcomes and toxicity between 3D conformal radiotherapy (3DCRT) and image-guided intensity-modulated radiotherapy (IG-IMRT) administered through helical tomotherapy in locally advanced rectal cancer (LARC) patients receiving preoperative chemoradiotherapy. We reviewed 144 p...

journal_title：Journal of radiation research

authors： Huang CM,Huang MY,Tsai HL,Huang CW,Ma CJ,Lin CH,Huang CJ,Wang JY

更新日期：2017-03-01 00:00:00

abstract：:Chronic irradiation with low-dose-rate 137Cs-γ rays inhibits the differentiation of human neural progenitor cells and influences the expression of proteins associated with several cellular functions. We aimed to determine whether such chronic irradiation influences the expression of proteins associated with PC12 cells...

journal_title：Journal of radiation research

authors： Shinsuke K,Junya K,Tomonobu U,Yoshiko K,Izumo N,Takahiko S

更新日期：2017-11-01 00:00:00

abstract：:A number of agents are now available for use in protecting against ionizing radiation. These radiation-protective agents, however, have many adverse effects. Efforts have been made to develop new radiation-protective agents for medical application. Here, we investigated whether a compound, polyethylenimine (PEI), whic...

journal_title：Journal of radiation research

authors： Hu Z,Xing Y,Qian Y,Chen X,Tu J,Ren L,Wang K,Chen Z

更新日期：2013-03-01 00:00:00

abstract：:Radiation-induced rescue effect (RIRE) in cells refers to the phenomenon where irradiated cells (IRCs) receive help from feedback signals produced by partnered bystander unirradiated cells (UIRCs) or from the conditioned medium (CM) that has previously conditioned the UIRCs. In the present work, we explored the role o...

journal_title：Journal of radiation research

authors： Pathikonda S,Cheng SH,Yu KN

更新日期：2020-05-22 00:00:00

abstract：:We generated low-flux X-ray micro-planar beams (MPBs) using a laboratory-scale industrial X-ray generator (60 kV/20 mA) with custom-made collimators with three different peak/pitch widths (50/200 μm, 100/400 μm, 50/400 μm). To evaluate normal skin reactions, the thighs of C3H/HeN mice were exposed to 100 and 200 Gy MP...

journal_title：Journal of radiation research

authors： Hong Z,Zenkoh J,Le B,Gerelchuluun A,Suzuki K,Moritake T,Washio M,Urakawa J,Tsuboi K

更新日期：2015-09-01 00:00:00

abstract：:Cytogenetic investigation of stable-type aberrations (translocations) was carried out with our improved methods on 28 elderly individuals in a high-background radiation area (HBRA) in China, and on 24 elderly individuals in a control area (CA). The level of radiation in HBRA is 3 to 5 times higher than in CA. The mean...

journal_title：Journal of radiation research

authors： Zhang W,Wang C,Chen D,Minamihisamatsu M,Morishima H,Yuan Y,Wei L,Sugahara T,Hayata I

更新日期：2004-09-01 00:00:00

abstract：:In Japan, the use of adjuvant radiotherapy after prostatectomy for prostate cancer has not increased compared with the use of salvage radiotherapy. We retrospectively evaluated the outcome of adjuvant radiotherapy together with prognostic factors of outcome in Japan. Between 2005 and 2007, a total of 87 patients were ...

journal_title：Journal of radiation research

authors： Aoki M,Mizowaki T,Akimoto T,Nakamura K,Ejima Y,Jingu K,Tamai Y,Nakajima N,Takemoto S,Kokubo M,Katoh H

更新日期：2014-05-01 00:00:00

abstract：:We evaluated toxicity and outcomes for patients with peripheral lung tumors treated with stereotactic body radiation therapy (SBRT) in a dose-escalation and dose-convergence study. A total of 15 patients were enrolled. SBRT was performed with 60 Gy in 5 fractions (fr.) prescribed to the 60% isodose line of maximum dos...

journal_title：Journal of radiation research

authors： Takeda A,Oku Y,Sanuki N,Eriguchi T,Aoki Y,Enomoto T,Kaneko T,Nishimura S,Kunieda E

更新日期：2014-09-01 00:00:00

abstract：:The aim of this study is to evaluate the potential radioprotective effects of N-acetylcysteine (NAC) against genotoxicity and cytotoxicity. The effect of WR-2721, as a representative of clinically used radioprotector, was compared with that of NAC, using the chromosomal aberration (CA) and micronucleus (MN) test syste...

journal_title：Journal of radiation research

authors： Demirel C,Kilçiksiz S,Ay OI,Gürgül S,Ay ME,Erdal N

更新日期：2009-01-01 00:00:00

abstract：:The aim of the study was to investigate the various effects of high linear energy transfer (LET) carbon ion (12C6+) and low LET X-ray radiation on MDA-MB-231 and MCF-7 human breast cancer cells and to explore the underlying mechanisms of radiation sensitivity. Cell proliferation, cell colony formation, cell cycle dist...

journal_title：Journal of radiation research

authors： Zhang Q,Kong Y,Yang Z,Liu Y,Liu R,Geng Y,Luo H,Zhang H,Li H,Feng S,Wang X

更新日期：2020-05-22 00:00:00

abstract：:We have examined the neutron energy dependency of cell killing and mutation induction at the hprt locus in Chinese hamster V79 cells. Monoenergetic neutrons at 0.32, 0.57, and 1.2 MeV were generated at the Hiroshima University Radiobiological Research Accelerator (HIRRAC) Facility, and were used to irradiate cells. Th...

journal_title：Journal of radiation research

authors： Kubota N,Okada S,Nagatomo S,Ozawa F,Inada T,Hill CK,Endo S,Komatsu K

更新日期：1999-12-01 00:00:00

abstract：:The study aimed to detect features of human serum proteome that were associated with exposure to ionizing radiation. The analyzed group consisted of 46 patients treated with radical radiotherapy for larynx cancer; patients were irradiated with total doses in a range from 51 to 72 Gy. Three consecutive blood samples we...

journal_title：Journal of radiation research

authors： Widłak P,Pietrowska M,Wojtkiewicz K,Rutkowski T,Wygoda A,Marczak L,Marczyk M,Polańska J,Walaszczyk A,Domińczyk I,Składowski K,Stobiecki M,Polański A

更新日期：2011-01-01 00:00:00

abstract：:To improve treatment conformity for prostate cancer, we investigated daily applicator displacement during high-dose-rate interstitial brachytherapy (HDR-ISBT). Thirty patients treated with HDR-ISBT as monotherapy were examined. All patients received a treatment dosage of 49 Gy per 7 fractions over 4 days. For dose adm...

journal_title：Journal of radiation research

authors： Takenaka T,Yoshida K,Ueda M,Yamazaki H,Miyake S,Tanaka E,Yoshida M,Yoshimura Y,Oka T,Honda K

更新日期：2012-01-01 00:00:00

abstract：:Although radon inhalation increases superoxide dismutase (SOD) activities in mouse organs, the mechanisms and pathways have not yet been fully clarified. The aim of this study was to determine the details of SOD activation in mouse brain tissue following the inhalation of radon at concentrations of 500 or 2000 Bq/m3 f...

journal_title：Journal of radiation research

authors： Kataoka T,Etani R,Kanzaki N,Kobashi Y,Yunoki Y,Ishida T,Sakoda A,Ishimori Y,Yamaoka K

更新日期：2017-11-01 00:00:00

abstract：:This study investigates whether in-room computed tomography (CT)-based adaptive treatment planning (ATP) is robust against interfractional location variations, namely, interfractional organ motions and/or applicator displacements, in 3D intracavitary brachytherapy (ICBT) for uterine cervical cancer. In ATP, the radiat...

journal_title：Journal of radiation research

authors： Oku Y,Arimura H,Nguyen TT,Hiraki Y,Toyota M,Saigo Y,Yoshiura T,Hirata H

更新日期：2016-11-01 00:00:00

abstract：:The purpose of this study was to compare single-arc (SA) and double-arc (DA) treatment plans, which are planning techniques often used in prostate cancer volumetric modulated arc therapy (VMAT), in the presence of intrafractional deformation (ID) to determine which technique is superior in terms of target dose coverag...

journal_title：Journal of radiation research

authors： Varnava M,Sumida I,Oda M,Kurosu K,Isohashi F,Seo Y,Otani K,Ogawa K

更新日期：2020-12-21 00:00:00

abstract：:Chromosome painting by fluorescence in situ hybridization (FISH) with a whole chromosome-specific DNA probe was used to detect chromosomal aberrations in lymphocytes from cancer patients given partial-body fractionated X-ray therapy. Six male patients with cancer of the stomach, prostate, lung, or hepatocellular carci...

journal_title：Journal of radiation research

authors： Matsuoka A,Yamada K,Hayashi M,Sofuni T

更新日期：1996-12-01 00:00:00

abstract：:The purpose of this study was to quantify the changes of tumor blood flow (BF) in cervical cancer after radiation therapy by using perfusion computed tomography (CT), and to examine the difference between maximum slope (MS) and single-input one-compartment model (SOCM) methods. Fourteen consecutive patients who receiv...

journal_title：Journal of radiation research

authors： Shibuya K,Tsushima Y,Horisoko E,Noda SE,Taketomi-Takahashi A,Ohno T,Amanuma M,Endo K,Nakano T

更新日期：2011-01-01 00:00:00

abstract：:This study determined whether dynamic F-18 FDG PET imaging could differentiate benign from malignant solitary pulmonary nodules (SPNs). Histopathologically confirmed SPNs (10-35 mm), 24 malignant and 10 benign, from 34 patients were studied through both dynamic and static F-18 FDG PET imaging of all patients. Volumes ...

journal_title：Journal of radiation research

authors： Huang YE,Lu HI,Liu FY,Huang YJ,Lin MC,Chen CF,Wang PW

更新日期：2012-01-01 00:00:00

abstract：:The direct biological effects of radiation, particularly accelerated heavy particle ions, on neurons are not fully known. Hence, the direct effect of carbon-ion beams on immature neurons was investigated by comparing to the effect of X-rays in vitro using primary hippocampal neurons. Primary neurons were prepared from...

journal_title：Journal of radiation research

authors： Kaminuma T,Suzuki Y,Shirai K,Mizui T,Noda SE,Yoshida Y,Funayama T,Takahashi T,Kobayashi Y,Shirao T,Nakano T

更新日期：2010-01-01 00:00:00

abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

journal_title：Journal of radiation research

authors： Takahashi S,Koshimoto C,Kubota Y

更新日期：1993-06-01 00:00:00

abstract：:This study investigated the radioprotective effect of Sipunculus nudus L. polysaccharide (SNP) in combination with WR-2721, rhIL-11 and rhG-CSF on irradiated mice. A total of 70 Imprinting Control Region (ICR) mice were divided into seven groups: the control group, the model group and five administration groups. All g...

journal_title：Journal of radiation research

authors： Jiang S,Shen X,Liu Y,He Y,Jiang D,Chen W

更新日期：2015-05-01 00:00:00

abstract：:An overview is given of the dose-response relationship for stable chromosome aberrations (i.e., translocations and inversions) in the peripheral blood lymphocytes of A-bomb survivors in Hiroshima. Special emphasis is placed on (i) the overdispersion of survivor cases with either unexpectedly high or low aberration fre...

journal_title：Journal of radiation research

authors： Awa AA,Nakano M,Ohtaki K,Kodama Y,Lucas J,Gray J

更新日期：1992-03-01 00:00:00

abstract：:This study is a subset analysis of a retrospective multicenter study performed in Japan and its purpose was to investigate the effectiveness of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from colorectal cancer. Local control (LC), freedom from further metastases, relapse-free survival and over...

journal_title：Journal of radiation research

authors： Yamamoto T,Niibe Y,Matsumoto Y,Onishi H,Aoki M,Nishikawa A,Oh RJ,Shintani T,Yahara K,Ozaki M,Manabe Y,Jingu K

更新日期：2020-11-16 00:00:00

abstract：:In our previous studies, we found that low-dose radiation inhibits oxidative stress-induced diseases due to increased antioxidants. Although these effects of low-dose radiation were demonstrated, further research was needed to clarify the effects. However, the analysis of oxidative stress is challenging, especially th...

journal_title：Journal of radiation research

authors： Kanzaki N,Kataoka T,Etani R,Sasaoka K,Kanagawa A,Yamaoka K

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The aim of this study is to evaluate the cost-effectiveness of proton beam therapy with cochlear dose reduction compared with conventional X-ray radiotherapy for medulloblastoma in childhood. METHODS:We developed a Markov model to describe health states of 6-year-old children with medulloblastoma after trea...

journal_title：Journal of radiation research

authors： Hirano E,Fuji H,Onoe T,Kumar V,Shirato H,Kawabuchi K

更新日期：2014-03-01 00:00:00

abstract：:In the last few years, hospital-based facilities for carbon-ion radiotherapy are being constructed and proposed in Europe and Asia. During the next few years, several new facilities will be opened for carbon-ion radiotherapy in the world. These facilities in operation or under construction are categorized in two types...

journal_title：Journal of radiation research

authors： Minohara S,Fukuda S,Kanematsu N,Takei Y,Furukawa T,Inaniwa T,Matsufuji N,Mori S,Noda K

更新日期：2010-01-01 00:00:00

abstract：:A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...

journal_title：Journal of radiation research

authors： Hoshi Y,Nomura T,Oda T,Iwasaki T,Fujita K,Ishikawa T,Kato A,Ikegami T,Sakai K,Tanooka H,Yamada T

更新日期：2000-06-01 00:00:00

abstract：:The aim of this study was to evaluate the effectiveness and tolerability of definitive chemo-radiation or radiotherapy alone in patients with esophageal cancer. We retrospectively analyzed the medical records of n = 238 patients with squamous cell carcinoma or adenocarcinoma of the esophagus treated with definitive ra...

journal_title：Journal of radiation research

authors： Haefner MF,Lang K,Krug D,Koerber SA,Uhlmann L,Kieser M,Debus J,Sterzing F

更新日期：2015-07-01 00:00:00

abstract：:Centrosomes function in proper cell division in animal cells. The centrosome consists of a pair of centrioles and the surrounding pericentriolar matrix (PCM). After cytokinesis, daughter cells each acquire one centrosome, which subsequently duplicates at the G1/S phase in a manner that is dependent upon CDK2/cyclin-E ...

journal_title：Journal of radiation research

authors： Shimada M,Komatsu K

更新日期：2009-07-01 00:00:00