Abstract：
:Natural killer (NK) cells respond rapidly to transformed, stressed, or virally infected cells and provide a first-line immune defense against pathogen invasion and cancer. Thought to involve short-lived effector cells that are armed for battle, NK cells were not previously known to contribute in recall responses to pathogen re-encounter. Here, we highlight recent discoveries demonstrating that NK cells are not limited to driving primary immune responses to foreign antigen but can mount secondary responses contributing to immune memory. We also further characterize the phenotype and function of long-lived memory NK cells generated during viral infection.
journal_name
Immunol Revjournal_title
Immunological reviewsauthors
Sun JC,Beilke JN,Lanier LLdoi
10.1111/j.1600-065X.2010.00900.xsubject
Has Abstractpub_date
2010-07-01 00:00:00pages
83-94eissn
0105-2896issn
1600-065Xpii
IMR900journal_volume
236pub_type
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journal_title：Immunological reviews
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journal_title：Immunological reviews
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1034/j.1600-065x.2003.00025.x
更新日期：2003-02-01 00:00:00
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更新日期：2010-03-01 00:00:00
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更新日期：2009-03-01 00:00:00
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更新日期：2010-03-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章
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更新日期：1986-12-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1600-065x.1998.tb01250.x
更新日期：1998-12-01 00:00:00
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更新日期：2012-11-01 00:00:00
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更新日期：2003-12-01 00:00:00
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更新日期：2014-01-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1600-065x.1984.tb00479.x
更新日期：1984-04-01 00:00:00
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更新日期：2017-09-01 00:00:00
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更新日期：2014-05-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1034/j.1600-065x.2001.1810116.x
更新日期：2001-06-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1600-065x.1991.tb00585.x
更新日期：1991-04-01 00:00:00
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更新日期：2006-04-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
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更新日期：2002-12-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
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更新日期：2009-09-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1600-065x.1991.tb00584.x
更新日期：1991-02-01 00:00:00
abstract：:Upon antigen recognition, T cells undergo substantial membrane and cytoskeletal rearrangements that lead to the formation of the immunological synapse and are necessary for subsequent T-cell activation. However, little is known about how membrane and cytoskeletal molecules interact during these processes. Here we disc...
journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1034/j.1600-065x.2002.18911.x
更新日期：2002-11-01 00:00:00
abstract：:T-cell development is a highly coordinated process that depends on interactions between thymocytes, thymic epithelium, and bone marrow (BM)-derived dendritic cells (DCs). Before entering the peripheral T-cell pool, thymocytes are subject to negative selection, a process that eliminates (or deletes) T cells with high a...
journal_title：Immunological reviews
pub_type： 杂志文章,评审
doi：10.1111/j.0105-2896.2006.00348.x
更新日期：2006-02-01 00:00:00
