Short CDAI: development and validation of a shortened and simplified Crohn's disease activity index.

abstract：:The genetic basis of antineutrophil cytoplasmic antibody, an important biomarker of inflammatory bowel disease (IBD), has never been thoroughly examined on a genome-wide scale. In this study, we performed a 2-stage genome-wide association study (GWAS) on antineutrophil cytoplasmic antibody in IBD cases. In the 2959 IB...

journal_title：Inflammatory bowel diseases

authors： Li D,Silverberg MS,Haritunians T,Dubinsky MC,Landers C,Stempak JM,Milgrom R,Guo X,Chen YD,Rotter JI,Taylor KD,McGovern DP,Targan SR

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Genetic susceptibility may play a more important role in the etiology of early-onset inflammatory bowel disease (IBD) than in late-onset IBD, and therefore pediatric-onset IBD patients can be expected to have a higher frequency of gene mutations. We aimed to determine genotypes and phenotypes of patients wit...

journal_title：Inflammatory bowel diseases

authors： de Ridder L,Weersma RK,Dijkstra G,van der Steege G,Benninga MA,Nolte IM,Taminiau JA,Hommes DW,Stokkers PC

更新日期：2007-09-01 00:00:00

abstract：:There is no standard practice in the induction of colitis by 2,4,6-trinitrobenzene sulfonic acid. In this review the current practice in 2,4,6-trinitrobenzene sulfonic acid colitis is studied using 20 recently published articles. We compare the different protocols, discuss the mechanism of disease and give recommendat...

journal_title：Inflammatory bowel diseases

authors： te Velde AA,Verstege MI,Hommes DW

更新日期：2006-10-01 00:00:00

abstract：:Diagnostics of inflammatory bowel diseases (IBDs) currently relies on a combination of biological and morphological tests. The current method of diagnostic remains a critical challenge for physicians in part due to their invasiveness and also for their limitations in term of diagnosis, prognosis, disease activity and ...

journal_title：Inflammatory bowel diseases

authors： Viennois E,Zhao Y,Merlin D

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the feasibility, acceptability, and effectiveness of a mindfulness-based intervention for patients with inflammatory bowel disease (MI-IBD). DESIGN:Treatment-as-usual control versus mindfulness-based stress reduction intervention. METHODS:Sixty patients participated in either t...

journal_title：Inflammatory bowel diseases

authors： Neilson K,Ftanou M,Monshat K,Salzberg M,Bell S,Kamm MA,Connell W,Knowles SR,Sevar K,Mancuso SG,Castle D

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Ideal biomarkers are required to be developed for the diagnosis and prediction of the treatment of inflammatory bowel disease (IBD). We have reported that alteration of N-linked oligosaccharides of immunoglobulin (Ig) G is a novel diagnostic marker of IBD. Oligosaccharide alterations of IgA, however, have no...

journal_title：Inflammatory bowel diseases

authors： Inoue T,Iijima H,Tajiri M,Shinzaki S,Shiraishi E,Hiyama S,Mukai A,Nakajima S,Iwatani H,Nishida T,Mizushima T,Yasui T,Isaka Y,Kanto T,Tsujii M,Miyoshi E,Wada Y,Takehara T

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Many chronic illnesses are accompanied by impaired cognitive functioning. In people with Inflammatory Bowel Disease (IBD), there is some research to suggest a decrement in verbal IQ (VIQ), when compared to people with Irritable Bowel Syndrome (IBS) and healthy controls. Although this is an important finding,...

journal_title：Inflammatory bowel diseases

authors： Dancey CP,Attree EA,Stuart G,Wilson C,Sonnet A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The incidence of vaccine-preventable disease is increasing. Several guidelines recommend annual influenza vaccination for patients with inflammatory bowel disease. METHODS:Using the Business Objects database of Clalit Health Services in the Tel Aviv district we identified all patients older than 18 years wi...

journal_title：Inflammatory bowel diseases

authors： Boltin D,Gingold-Belfer R,Kimchi NA,Ben-Bassat O,Niv Y,Birkenfeld S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:We aimed to determine the prevalence of adverse childhood experiences (ACEs) in persons with inflammatory bowel disease (IBD) and whether having ACEs was associated with health care utilization post-IBD diagnosis. METHOD:Three hundred forty-five participants from the population-based Manitoba IBD Cohort Stu...

journal_title：Inflammatory bowel diseases

authors： Witges KM,Bernstein CN,Sexton KA,Afifi T,Walker JR,Nugent Z,Lix LM

更新日期：2019-09-18 00:00:00

abstract：BACKGROUND:A total of 254 senior consultant gastroenterologists with valid e-mail addresses were identified from the membership list of the British Society of Gastroenterology (BSG) 2007. METHODS:They were sent by e-mail a questionnaire which dealt with aspects of clinical practice and addressed cancer prevention in u...

journal_title：Inflammatory bowel diseases

authors： Mayberry H,Moshkovska T,Mayberry JF

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Epithelial barrier disturbance is thought to contribute to the pathogenesis of inflammatory bowel diseases; however, it remains unclear whether it is a primary defect participating to the onset of inflammation or only a consequence of sustained inflammation. METHODS:A time course study of epithelial barrier...

journal_title：Inflammatory bowel diseases

authors： Suenaert P,Maerten P,Van Assche G,Van Driessche W,Geboes K,Bulteel V,Simaels J,Augustijns P,Ceuppens JL,Rutgeerts P,Perrier C

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Current therapy for inflammatory bowel disease (IBD) patients often involves agents that suppress the immune system, placing patients at an increased risk for developing infections, of which several are potentially vaccine preventable. Many IBD patients are not being vaccinated appropriately. The aims of thi...

journal_title：Inflammatory bowel diseases

authors： Wasan SK,Coukos JA,Farraye FA

更新日期：2011-12-01 00:00:00

abstract：:We report a case of a 40-year-old woman who had received infliximab for perianal Crohn's disease. After six infusions of infliximab, the patient developed staphylococcal pneumonia resulting in fatal adult respiratory distress syndrome. The case is discussed in the context of the toxicity profile of infliximab. ...

journal_title：Inflammatory bowel diseases

authors： Herrlinger KR,Borutta A,Meinhardt G,Stange EF,Fellermann K

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel diseases (IBDs) are chronic illnesses that require frequent and regular healthcare contact. Regular maintenance care may reduce complications or the need for hospitalization. Availability of physicians may be an important determinant of IBD hospitalizations. METHODS:Using 2008 inpatient d...

journal_title：Inflammatory bowel diseases

authors： Ananthakrishnan AN,McGinley EL,Binion DG,Saeian K

更新日期：2011-02-01 00:00:00

abstract：Background:Sarcopenia is associated with increased morbidity and mortality in oncologic and transplant surgery. It has a high incidence in chronic inflammatory states including inflammatory bowel disease (IBD). The validity of existing data in IBD and of sarcopenia's correlation with surgical outcomes is limited. Meth...

journal_title：Inflammatory bowel diseases

authors： Ryan E,McNicholas D,Creavin B,Kelly ME,Walsh T,Beddy D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Improved treatment approaches for ulcerative colitis (UC), including novel medications, might reduce the need for colectomy. We performed a retrospective cohort study of adult patients (age 18-64) with UC in the United States to examine time trends for colectomy and biologic use from 2007 to 2016. METHODS:W...

journal_title：Inflammatory bowel diseases

authors： Barnes EL,Jiang Y,Kappelman MD,Long MD,Sandler RS,Kinlaw AC,Herfarth HH

更新日期：2020-07-17 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) affects people during their prime reproductive years. The thiopurines (6-mercaptopurine and azathioprine), commonly used for induction and maintenance of remission, are U.S. Food and Drug Administration (FDA) pregnancy category D, raising concern for fetal risk. We performed ...

journal_title：Inflammatory bowel diseases

authors： Akbari M,Shah S,Velayos FS,Mahadevan U,Cheifetz AS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Mesalazine preparations are widely used to treat mild to moderately severe ulcerative colitis (UC). We compared once-daily administration of oral mesalazine in patients with quiescent UC with the established 3-times-daily prescription, assessing the efficacy and safety of each method in maintaining remission...

journal_title：Inflammatory bowel diseases

authors： Watanabe M,Hanai H,Nishino H,Yokoyama T,Terada T,Suzuki Y

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Although magnetic resonance imaging (MRI) is an increasingly used diagnostic tool in the assessment of inflammatory bowel disease (IBD) in humans, diagnosis and quantitation of intestinal inflammation in animal models of IBD still depends on ex vivo techniques. The aim of this study was to evaluate whether h...

journal_title：Inflammatory bowel diseases

authors： Michael S,Keubler LM,Smoczek A,Meier M,Gunzer F,Pöhlmann C,Krause-Buchholz U,Hedrich HJ,Bleich A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The etiology of ulcerative colitis (UC) and Crohn's disease (CD) involves both genetic and environmental components. Multiple UC and CD susceptibility genes have been identified through genome-wide association studies and subsequent meta-analyses. These studies have also highlighted the presence of genes com...

journal_title：Inflammatory bowel diseases

authors： Doecke JD,Simms LA,Zhao ZZ,Huang N,Hanigan K,Krishnaprasad K,Roberts RL,Andrews JM,Mahy G,Bampton P,Lewindon P,Florin T,Lawrance IC,Gearry RB,Montgomery GW,Radford-Smith GL

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:The efficacy of anti-tumor necrosis factor monoclonal antibody (anti-TNF mAb) for Crohn's disease (CD) is well established, and anti-interleukin-6 receptor (anti-IL-6R) mAb has also been reported to be effective in CD. It is, however, unclear if the efficacy and mechanisms of both agents are different in CD ...

journal_title：Inflammatory bowel diseases

authors： Terabe F,Fujimoto M,Serada S,Shinzaki S,Iijima H,Tsujii M,Hayashi N,Nomura S,Kawahata H,Jang MH,Miyasaka M,Mihara M,Ohsugi Y,Kishimoto T,Naka T

更新日期：2011-02-01 00:00:00

abstract：:Intestinal fibrosis is a common and serious complication of Crohn's disease (CD) and as it can occur at any time during the disease course, it is crucial to identify patients at risk. The aim is not only to understand the pathophysiology of fibrogenesis but to be able to accurately inform subjects about their disease ...

journal_title：Inflammatory bowel diseases

authors： Rieder F,Lawrance IC,Leite A,Sans M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Guidelines mandate screening for latent tuberculosis infection (LTBI) prior to anti-tumor necrosis factor (anti-TNF) therapy in patients with inflammatory bowel disease (IBD). However, many are already on immunosuppressive therapy (IST) that may affect the precision of the Tuberculin skin test (TST). Our aim...

journal_title：Inflammatory bowel diseases

authors： Shahidi N,Fu YT,Qian H,Bressler B

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The dinitrofluorobenzene/dinitrosulfonic acid (DNFB/DNS) model was originally described as an experimental model of intestinal inflammation resembling human ulcerative colitis (UC). Due to the absence of acceptable UC experimental models for pharmacological preclinical assays, here we examine the immune resp...

journal_title：Inflammatory bowel diseases

authors： Bailón E,Cueto-Sola M,Utrilla P,Nieto A,Garrido-Mesa N,Celada A,Zarzuelo A,Xaus J,Gálvez J,Comalada M

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To describe the reported health-related quality of life (HRQOL) in children and adolescents with inflammatory bowel disease (IBD) after attending an IBD summer camp. METHODS:A prospective analysis of quality of life was completed at an overnight camp that was exclusively for patients with IBD, which was sponso...

journal_title：Inflammatory bowel diseases

authors： Shepanski MA,Hurd LB,Culton K,Markowitz JE,Mamula P,Baldassano RN

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Differentiating between enteric infection and relapse of inflammatory bowel disease (IBD) is a common clinical challenge. Few studies have evaluated the impact of multiplex gastrointestinal polymerase chain reaction (GI PCR) pathogen panels on clinical practice compared to stool culture. Our aim was to compa...

journal_title：Inflammatory bowel diseases

authors： Hong S,Zaki TA,Main M,Hine AM,Chang S,Hudesman D,Axelrad JE

更新日期：2021-01-02 00:00:00

abstract：Background:We assessed the comparative efficacy of different dysplasia detection techniques in patients with ulcerative colitis (UC) through a network meta-analysis and rated the quality of evidence using GRADE approach. Methods:Through a systematic literature review of multiple databases through June 30, 2017, we ide...

journal_title：Inflammatory bowel diseases

authors： Bessissow T,Dulai PS,Restellini S,Landry T,Bisschops R,Murad MH,Singh S

更新日期：2018-11-29 00:00:00

abstract：:Restorative proctocolectomy with ileal-pouch anal anastomosis (RPC) is the operation of choice for ulcerative colitis (UC) patients requiring surgery. It is also used for patients with familial adenomatous polyposis (FAP). Pouchitis accounts for 10% of pouch failures. It is an idiopathic inflammatory condition that ma...

journal_title：Inflammatory bowel diseases

authors： Landy J,Al-Hassi HO,McLaughlin SD,Knight SC,Ciclitira PJ,Nicholls RJ,Clark SK,Hart AL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Long-term enteral nutrition may maintain clinical and endoscopic remission in patients with Crohn's disease (CD). The aim of this prospective study was to investigate the impacts of long-term enteral nutrition on clinical and endoscopic disease activities and mucosal tissue cytokines in patients with quiesce...

journal_title：Inflammatory bowel diseases

authors： Yamamoto T,Nakahigashi M,Saniabadi AR,Iwata T,Maruyama Y,Umegae S,Matsumoto K

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Drug concentration monitoring may be useful to guide therapeutic adjustments for anti-tumor necrosis factor agents in Crohn's disease. The relationship between serum adalimumab concentrations and clinical outcomes was assessed using data from CLinical Assessment of Adalimumab Safety and Efficacy Studied as I...

journal_title：Inflammatory bowel diseases

authors： Chiu YL,Rubin DT,Vermeire S,Louis E,Robinson AM,Lomax KG,Pollack PF,Paulson SK

更新日期：2013-05-01 00:00:00